Authors
Tieme WP Janssen, Dirk J Heslenfeld, Rosa van Mourik, Katleen Geladé, Athanasios Maras, Jaap Oosterlaan
Publication date
2018/5
Journal
Journal of attention disorders
Volume
22
Issue
7
Pages
639-650
Publisher
SAGE Publications
Description
Objective
Deficits in response inhibition figure prominently in models of ADHD; however, attentional deficiencies may better explain previous findings of impaired response inhibition in ADHD. We tested this hypothesis at the neurophysiological level.
Method
Dense array ERPs (event-related potentials) were obtained for 46 children with ADHD and 51 controls using the stop-signal task (SST). Early and late components were compared between groups. N2 and P3 components were localized with LAURA distributed linear inverse solution.
Results
A success-related N1 modulation was only apparent in the ADHD group. N2 and P3 amplitudes were reduced in ADHD. During the successful inhibition N2, the ADHD group showed reduced activation in right inferior frontal gyrus (rIFG), supplementary motor area (SMA), and right temporoparietal junction (rTPJ), and during failed inhibition in the rIFG. During the successful …
Total citations
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