Authors
Daniel von Rhein, Christian F Beckmann, Barbara Franke, Jaap Oosterlaan, Dirk J Heslenfeld, Pieter J Hoekstra, Catharina A Hartman, Marjolein Luman, Stephen V Faraone, Roshan Cools, Jan K Buitelaar, Maarten Mennes
Publication date
2017/5
Journal
Human brain mapping
Volume
38
Issue
5
Pages
2359-2369
Description
Introduction
Reward processing is a key aspect of cognitive control processes, putatively instantiated by mesolimbic and mesocortical brain circuits. Deficient signaling within these circuits has been associated with psychopathology. We applied a network discovery approach to assess specific functional networks associated with reward processing in participants with attention‐deficit/hyperactivity disorder (ADHD).
Methods
To describe task‐related processes in terms of integrated functional networks, we applied independent component analysis (ICA) to task response maps of 60 healthy participants who performed a monetary incentive delay (MID) task. The resulting components were interpreted on the basis of their similarity with group‐level task responses as well as their similarity with brain networks derived from resting state fMRI analyses. ADHD‐related effects on network characteristics including functional …
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