| Generation of pathogenic TH 17 cells in the absence of TGF-β signalling K Ghoreschi, A Laurence, XP Yang, CM Tato, MJ McGeachy, JE Konkel, ... Nature 467 (7318), 967-971, 2010 | 1716 | 2010 |
| Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5 XP Yang, K Ghoreschi, SM Steward-Tharp, J Rodriguez-Canales, J Zhu, ... Nature immunology 12 (3), 247-254, 2011 | 689 | 2011 |
| Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study J Tian, X Yuan, J Xiao, Q Zhong, C Yang, B Liu, Y Cai, Z Lu, J Wang, ... The Lancet Oncology 21 (7), 893-903, 2020 | 603 | 2020 |
| Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1 K Hirahara, K Ghoreschi, XP Yang, H Takahashi, A Laurence, G Vahedi, ... Immunity 36 (6), 1017-1030, 2012 | 299 | 2012 |
| Signal transduction pathways and transcriptional regulation in Th17 cell differentiation K Hirahara, K Ghoreschi, A Laurence, XP Yang, Y Kanno, JJ O'Shea Cytokine & growth factor reviews 21 (6), 425-434, 2010 | 270 | 2010 |
| T helper 17 cell heterogeneity and pathogenicity in autoimmune disease K Ghoreschi, A Laurence, XP Yang, K Hirahara, JJ O'Shea Trends in immunology 32 (9), 395-401, 2011 | 265 | 2011 |
| Lactate in the tumour microenvironment: From immune modulation to therapy ZH Wang, WB Peng, P Zhang, XP Yang, Q Zhou EBioMedicine 73, 103627, 2021 | 159 | 2021 |
| Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression N Liu, J Luo, D Kuang, S Xu, Y Duan, Y Xia, Z Wei, X Xie, B Yin, F Chen, ... The Journal of clinical investigation 129 (2), 631-646, 2019 | 150 | 2019 |
| EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion XP Yang, K Jiang, K Hirahara, G Vahedi, B Afzali, G Sciume, M Bonelli, ... Scientific reports 5 (1), 1-14, 2015 | 146 | 2015 |
| Helper T‐cell differentiation and plasticity: insights from epigenetics K Hirahara, G Vahedi, K Ghoreschi, XP Yang, S Nakayamada, Y Kanno, ... Immunology 134 (3), 235-245, 2011 | 142 | 2011 |
| A Unique Population of Regulatory T Cells in Heart Potentiates Cardiac Protection from Myocardial Infarction XC Ni Xia 1, Yuzhi Lu 1, Muyang Gu 1, Nana Li 1, Meilin Liu 1, Jiao Jiao 1 ... circulation, 2020 | 127 | 2020 |
| Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation M Yu, Z Peng, M Qin, Y Liu, J Wang, C Zhang, J Lin, T Dong, L Wang, S Li, ... Molecular Cell 81 (6), 1216-1230. e9, 2021 | 123 | 2021 |
| Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation S Radtke, S Wüller, X Yang, BE Lippok, B Mütze, C Mais, ... Journal of cell science 123 (6), 947-959, 2010 | 121 | 2010 |
| The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion Y Xia, N Liu, X Xie, G Bi, H Ba, L Li, J Zhang, X Deng, Y Yao, Z Tang, ... Autophagy 15 (6), 960-975, 2019 | 116 | 2019 |
| The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell–Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9–Producing T Cells AC Richard, C Tan, ET Hawley, J Gomez-Rodriguez, R Goswami, ... The Journal of Immunology 194 (8), 3567-3582, 2015 | 106 | 2015 |
| Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model C Tkaczyk, MM Hamilton, V Datta, XP Yang, JJ Hilliard, GL Stephens, ... PLoS One 8 (10), e75103, 2013 | 94 | 2013 |
| Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune C Tkaczyk, MM Hamilton, V Datta, XP Yang, JJ Hilliard | 94* | 2013 |
| Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells Z Zhang, G Lin, Y Yan, X Li, Y Hu, J Wang, B Yin, Y Wu, Z Li, XP Yang Oncogene 37 (25), 3456-3470, 2018 | 84 | 2018 |
| STAT1 mediates transmembrane TNF-alpha-induced formation of death-inducing signaling complex and apoptotic signaling via TNFR1 Y Jiang, M Yu, X Hu, L Han, K Yang, H Ba, Z Zhang, B Yin, XP Yang, Z Li, ... Cell Death & Differentiation 24 (4), 660-671, 2017 | 79 | 2017 |
| The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes P Pandiyan, XP Yang, SS Saravanamuthu, L Zheng, S Ishihara, ... The Journal of Immunology 189 (9), 4237-4246, 2012 | 78 | 2012 |
