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Xin Yang
Xin Yang
Verified email at medschl.cam.ac.uk
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Year
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
N Mavaddat, K Michailidou, J Dennis, M Lush, L Fachal, A Lee, JP Tyrer, ...
The American Journal of Human Genetics 104 (1), 21-34, 2019
9032019
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families
X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ...
Journal of clinical oncology 38 (7), 674-685, 2020
3512020
Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D
X Yang, H Song, G Leslie, C Engel, E Hahnen, B Auber, J Horváth, K Kast, ...
JNCI: Journal of the National Cancer Institute 112 (12), 1242-1250, 2020
1402020
Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants
S Li, V Silvestri, G Leslie, TR Rebbeck, SL Neuhausen, JL Hopper, ...
Journal of Clinical Oncology 40 (14), 1529-1541, 2022
1372022
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
DR Barnes, MA Rookus, L McGuffog, G Leslie, TM Mooij, J Dennis, ...
Genetics in Medicine 22 (10), 1653-1666, 2020
1012020
Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells
CJM Bell, Y Sun, UM Nowak, J Clark, S Howlett, ML Pekalski, X Yang, ...
Journal of Autoimmunity 56, 66-80, 2015
952015
Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
RC Ferreira, HZ Simons, WS Thompson, DB Rainbow, X Yang, AJ Cutler, ...
Journal of Autoimmunity 84, 75-86, 2017
802017
Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors
A Lee, X Yang, J Tyrer, A Gentry-Maharaj, A Ryan, N Mavaddat, ...
Journal of medical genetics 59 (7), 632-643, 2022
462022
Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study
X Yang, G Leslie, A Gentry-Maharaj, A Ryan, M Intermaggio, A Lee, ...
Journal of medical genetics 55 (8), 546-554, 2018
452018
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study
X Yang, M Eriksson, K Czene, A Lee, G Leslie, M Lush, J Wang, J Dennis, ...
Journal of medical genetics 59 (12), 1196-1205, 2022
362022
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
EO Dareng, JP Tyrer, DR Barnes, MR Jones, X Yang, KKH Aben, ...
European Journal of Human Genetics 30 (3), 349-362, 2022
332022
External validation of risk prediction models incorporating common genetic variants for incident colorectal cancer using UK Biobank
CL Saunders, B Kilian, DJ Thompson, LJ McGeoch, SJ Griffin, ...
Cancer Prevention Research 13 (6), 509-520, 2020
292020
Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores
DR Barnes, V Silvestri, G Leslie, L McGuffog, J Dennis, X Yang, J Adlard, ...
JNCI: Journal of the National Cancer Institute 114 (1), 109-122, 2022
262022
Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing
DB Rainbow, X Yang, O Burren, ML Pekalski, DJ Smyth, MDR Klarqvist, ...
European Journal of Immunology 45 (11), 3200, 2015
252015
Population study of ovarian cancer risk prediction for targeted screening and prevention
F Gaba, O Blyuss, X Liu, S Goyal, N Lahoti, D Chandrasekaran, M Kurzer, ...
Cancers 12 (5), 1241, 2020
232020
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
H Li, C Engel, M De la Hoya, P Peterlongo, D Yannoukakos, L Livraghi, ...
Genetics in Medicine 24 (1), 119-129, 2022
152022
CanRisk-prostate: a comprehensive, externally validated risk model for the prediction of future prostate cancer
T Nyberg, MN Brook, L Ficorella, A Lee, J Dennis, X Yang, N Wilcox, ...
Journal of Clinical Oncology 41 (5), 1092, 2023
122023
Polygenic scores in cancer
X Yang, S Kar, AC Antoniou, PDP Pharoah
Nature reviews Cancer 23 (9), 619-630, 2023
82023
Extra-binomial variation approach for analysis of pooled DNA sequencing data
X Yang, JA Todd, D Clayton, C Wallace
Bioinformatics 28 (22), 2898-2904, 2012
72012
J Med Genet
X Yang, M Eriksson, K Czene
52022
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