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TK Kwon
TK Kwon
Associate Director, AstraZeneca
Verified email at astrazeneca.net
Title
Cited by
Cited by
Year
Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics
T Kwon, AL Harris, A Rossi, TA Bargiello
Journal of General Physiology 138 (5), 475-493, 2011
882011
Voltage-dependent conformational changes in connexin channels
TA Bargiello, Q Tang, S Oh, T Kwon
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (8), 1807-1822, 2012
762012
Attenuation of synaptic potentials in dendritic spines
T Kwon, M Sakamoto, DS Peterka, R Yuste
Cell reports 20 (5), 1100-1110, 2017
752017
Deconvolution of voltage sensor time series and electro-diffusion modeling reveal the role of spine geometry in controlling synaptic strength
J Cartailler, T Kwon, R Yuste, D Holcman
Neuron 97 (5), 1126-1136. e10, 2018
472018
Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states
TA Bargiello, S Oh, Q Tang, NK Bargiello, TL Dowd, T Kwon
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (1), 22-39, 2018
402018
Molecular dynamics simulations of the Cx26 hemichannel: insights into voltage-dependent loop-gating
T Kwon, B Roux, S Jo, JB Klauda, AL Harris, TA Bargiello
Biophysical journal 102 (6), 1341-1351, 2012
402012
Ultrastructural, molecular and functional mapping of GABAergic synapses on dendritic spines and shafts of neocortical pyramidal neurons
T Kwon, A Merchán-Pérez, EM Rial Verde, JR Rodríguez, J DeFelipe, ...
Cerebral Cortex 29 (7), 2771-2781, 2019
392019
Voltage-dependent gating of the Cx32* 43E1 hemichannel: conformational changes at the channel entrances
T Kwon, Q Tang, TA Bargiello
Journal of general Physiology 141 (2), 243-259, 2013
272013
Functional requirement for a highly conserved charged residue at position 75 in the gap junction protein connexin 32
CK Abrams, M Islam, R Mahmoud, T Kwon, TA Bargiello, MM Freidin
Journal of Biological Chemistry 288 (5), 3609-3619, 2013
252013
Endothelial cells are heterogeneous in different brain regions and are dramatically altered in alzheimer's disease
A Bryant, Z Li, R Jayakumar, A Serrano-Pozo, B Woost, M Hu, ...
Journal of Neuroscience 43 (24), 4541-4557, 2023
102023
Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
JD Manos, CN Preiss, N Venkat, J Tamm, P Reinhardt, T Kwon, J Wu, ...
Iscience 25 (1), 2022
92022
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease
A Serrano-Pozo, Z Li, ME Woodbury, C Muñoz-Castro, A Wachter, ...
BioRxiv, 2022.12. 03.518999, 2022
62022
The carboxyl terminal residues 220–283 are not required for voltage gating of a chimeric connexin32 hemichannel
T Kwon, TL Dowd, TA Bargiello
Biophysical journal 105 (6), 1376-1382, 2013
52013
Deconvolution of voltage sensor time series and electro-diffusion modeling of synaptic input in dendritic spines
J Cartailler, T Kwon, R Yuste, D Holcman
Available at SSRN 3155925, 2017
12017
Functional characterization of a single nucleotide polymorphism associated with Alzheimer’s disease in a hiPSC-based neuron model
LR Stolzenburg, S Esmaeeli, AS Kulkarni, E Murphy, T Kwon, C Preiss, ...
Plos one 18 (9), e0291029, 2023
2023
Microglia show distinct tau associated subpopulations along tau spreading in human Alzheimer’s disease
A Wachter, ME Woodbury, A Abdourahman, RE Bennett, G Lin, T Kwon, ...
Alzheimer's & Dementia 19, e062092, 2023
2023
A brain atlas of astrocyte transcriptomics unveils complex states and responses to Alzheimer’s disease neuropathology
A Serrano‐Pozo, Z Li, ME Woodbury, A Wachter, AG Bryant, A Noori, ...
Alzheimer's & Dementia 18, e060866, 2022
2022
Transcriptomic Differences in Endothelial Cells Across Five Brain Regions in Normal Aging and Alzheimer's Disease
AG Bryant, Z Li, A Serrano‐Pozo, ME Woodbury, A Wachter, G Lin, ...
Alzheimer's & Dementia 18, e059018, 2022
2022
Tau pathology vulnerable neuronal subpopulation in Alzheimer’s disease
T Kwon, G Lin, SE Chancellor, A Wachter, A Abdourahman, RE Bennett, ...
Alzheimer's & Dementia 18, e063430, 2022
2022
Electro-diffusion modulation of synaptic input in dendritic spines using deconvolved voltage sensor time series
J Cartailler, T Kwon, R Yuste, D Holcman
bioRxiv, 097279, 2016
2016
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