| Biochemical and pharmacological characterization of YM-60828, a newly synthesized and orally active inhibitor of human factor Xa Y Taniuchi, Y Sakai, N Hisamichi, M Kayama, Y Mano, K Sato, ... Thrombosis and haemostasis 79 (03), 543-548, 1998 | 104 | 1998 |
| Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance–associated protein 2 Y Mano, T Usui, H Kamimura Biopharmaceutics & drug disposition 28 (1), 13-18, 2007 | 91 | 2007 |
| Hematocrit-independent recovery is a key for bioanalysis using volumetric absorptive microsampling devices, MitraTM Y Mano, K Kita, K Kusano Bioanalysis 7 (15), 1821-1829, 2015 | 75 | 2015 |
| The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver Y Mano, T Usui, H Kamimura Drug metabolism and disposition 35 (11), 2040-2044, 2007 | 71 | 2007 |
| Investigation of the high partition of YM992, a novel antidepressant, in rat brain ‐ in vitro and in vivo evidence for the high binding in brain and the high … Y Mano, S Higuchi, H Kamimura Biopharmaceutics & drug disposition 23 (9), 351-360, 2002 | 50 | 2002 |
| Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver Y Mano, T Usui, H Kamimura Drug metabolism and disposition 35 (7), 1182-1187, 2007 | 49 | 2007 |
| Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition K Kita, Y Mano Journal of Pharmaceutical and Biomedical Analysis 143, 168-175, 2017 | 48 | 2017 |
| High-performance liquid chromatography–tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid … Y Mano, O Takenaka, K Kusano Journal of Pharmaceutical and Biomedical Analysis 107, 56-62, 2015 | 40 | 2015 |
| Contribution of UDP-glucuronosyltransferases 1A9 and 2B7 to the glucuronidation of indomethacin in the human liver Y Mano, T Usui, H Kamimura European journal of clinical pharmacology 63, 289-296, 2007 | 39 | 2007 |
| Inhibitory potential of nonsteroidal anti-inflammatory drugs on UDP-glucuronosyltransferase 2B7 in human liver microsomes Y Mano, T Usui, H Kamimura European journal of clinical pharmacology 63, 211-216, 2007 | 37 | 2007 |
| In vitro inhibitory effects of non‐steroidal anti‐inflammatory drugs on 4‐methylumbelliferone glucuronidation in recombinant human UDP‐glucuronosyltransferase … Y Mano, T Usui, H Kamimura Biopharmaceutics & drug disposition 27 (1), 1-6, 2006 | 33 | 2006 |
| Effects of β‐estradiol and propofol on the 4‐methylumbelliferone glucuronidation in recombinant human UGT isozymes 1A1, 1A8 and 1A9 Y Mano, T Usui, H Kamimura Biopharmaceutics & drug disposition 25 (8), 339-344, 2004 | 32 | 2004 |
| Application of a volumetric absorptive microsampling device to a pharmacokinetic study of tacrolimus in rats: comparison with wet blood and plasma K Kita, K Noritake, Y Mano European Journal of Drug Metabolism and Pharmacokinetics 44, 91-102, 2019 | 31 | 2019 |
| In Vitro inhibitory effects of non‐steroidal antiinflammatory drugs on UDP‐glucuronosyltransferase 1A1‐catalysed estradiol 3β‐glucuronidation in human liver … Y Mano, T Usui, H Kamimura Biopharmaceutics & drug disposition 26 (1), 35-39, 2005 | 31 | 2005 |
| A validated LC–MS/MS method of total and unbound lenvatinib quantification in human serum for protein binding studies by equilibrium dialysis Y Mano, K Kusano Journal of pharmaceutical and biomedical analysis 114, 82-87, 2015 | 30 | 2015 |
| Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes Y Mano, T Usui, H Kamimura Drug metabolism and disposition 35 (4), 602-606, 2007 | 30 | 2007 |
| HPLC with fluorescence detection assay of perampanel, a novel AMPA receptor antagonist, in human plasma for clinical pharmacokinetic studies Y Mano, O Takenaka, K Kusano Biomedical Chromatography 29 (10), 1589-1593, 2015 | 27 | 2015 |
| Identification of human UDP-glucuronosyltransferase responsible for the glucuronidation of niflumic acid in human liver Y Mano, T Usui, H Kamimura Pharmaceutical research 23, 1502-1508, 2006 | 22 | 2006 |
| Method validation studies and an inter-laboratory cross validation study of lenvatinib assay in human plasma using LC-MS/MS Y Mano Practical Laboratory Medicine 12, e00103, 2018 | 19 | 2018 |
| Species differences in inhibition potential of nonsteroidal anti-inflammatory drugs against estradiol 3β-glucuronidation between rats, dogs, and humans Y Mano, T Usui, H Kamimura Journal of pharmaceutical sciences 97 (7), 2805-2810, 2008 | 17 | 2008 |
