| A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types S Jamieson, JU Flanagan, S Kolekar, C Buchanan, JD Kendall, WJ Lee, ... Biochemical Journal 438 (1), 53-62, 2011 | 176 | 2011 |
| Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis G Bashiri, AM Rehan, DR Greenwood, JMJ Dickson, EN Baker PloS one 5 (12), e15803, 2010 | 143 | 2010 |
| Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypicaltyrosine kinase with a key role in CDK1 regulation CJ Squire, JM Dickson, I Ivanovic, EN Baker Structure 13 (4), 541-550, 2005 | 130 | 2005 |
| Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed Y Yosaatmadja, S Silva, JM Dickson, AV Patterson, JB Smaill, ... Journal of structural biology 192 (3), 539-544, 2015 | 127 | 2015 |
| Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism PM Brown, TT Caradoc-Davies, JMJ Dickson, GJS Cooper, KM Loomes, ... Proceedings of the National Academy of Sciences 103 (41), 15032-15037, 2006 | 115 | 2006 |
| Comprehensive analysis of SARS‐CoV‐2 antibody dynamics in New Zealand AL Whitcombe, R McGregor, A Craigie, A James, R Charlewood, ... Clinical & translational immunology 10 (3), e1261, 2021 | 58 | 2021 |
| Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo [3, 4-c] carbazole-1, 3 (2H, 6H)-diones as inhibitors of Wee1 and Chk1 … JB Smaill, EN Baker, RJ Booth, AJ Bridges, JM Dickson, EM Dobrusin, ... European journal of medicinal chemistry 43 (6), 1276-1296, 2008 | 33 | 2008 |
| Enzyme activity effects of N-terminal His-tag attached to catalytic sub-unit of phosphoinositide-3-kinase JMJ Dickson, WJ Lee, PR Shepherd, CM Buchanan Bioscience reports 33 (6), e00079, 2013 | 31 | 2013 |
| Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism RD Bunker, EMM Bulloch, JMJ Dickson, KM Loomes, EN Baker Journal of Biological Chemistry 288 (3), 1643-1652, 2013 | 31 | 2013 |
| Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity CM Buchanan, JMJ Dickson, WJ Lee, MA Guthridge, JD Kendall, ... PloS one 8 (8), e71337, 2013 | 21 | 2013 |
| Expression, purification and characterisation of GIGANTEA: a circadian clock-controlled regulator of photoperiodic flowering in plants MM Black, C Stockum, JM Dickson, J Putterill, VL Arcus Protein Expression and Purification 76 (2), 197-204, 2011 | 17 | 2011 |
| Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474 AC Giddens, SA Gamage, JD Kendall, WJ Lee, BC Baguley, ... Bioorganic & Medicinal Chemistry 27 (8), 1529-1545, 2019 | 16 | 2019 |
| Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide J Le Nours, EMM Bulloch, Z Zhang, DR Greenwood, MJ Middleditch, ... Journal of Biological Chemistry 286 (47), 40706-40716, 2011 | 15 | 2011 |
| Structures of Glycinamide Ribonucleotide Transformylase (PurN) from Mycobacterium tuberculosis Reveal a Novel Dimer with Relevance to Drug Discovery Z Zhang, TT Caradoc-Davies, JM Dickson, EN Baker, CJ Squire Journal of molecular biology 389 (4), 722-733, 2009 | 15 | 2009 |
| Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase PM Brown, TT Caradoc-Davies, JM Dickson, GJS Cooper, KM Loomes, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 15 | 2006 |
| Family 34 glycosyltransferase (GT34) genes and proteins in Pinus radiata (radiata pine) and Pinus taeda (loblolly pine) CP Ade, F Bemm, JMJ Dickson, C Walter, PJ Harris The Plant Journal 78 (2), 305-318, 2014 | 14 | 2014 |
| Collaborative networks enable the rapid establishment of serological assays for SARS-CoV-2 during nationwide lockdown in New Zealand R McGregor, AL Whitcombe, CR Sheen, JM Dickson, CL Day, LH Carlton, ... PeerJ 8, e9863, 2020 | 13 | 2020 |
| High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds J Wang, GQ Gong, Y Zhou, WJ Lee, CM Buchanan, WA Denny, ... Acta Pharmacologica Sinica 39 (11), 1816-1822, 2018 | 12 | 2018 |
| Synthesis and Evaluation of Imidazo[1,2‐a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3‐Kinase Inhibitors SA Gamage, JA Spicer, KY Tsang, PD O'Connor, JU Flanagan, WJ Lee, ... Chemistry–An Asian Journal 14 (8), 1249-1261, 2019 | 10 | 2019 |
| Charting elimination in the pandemic: a SARS-CoV-2 serosurvey of blood donors in New Zealand LH Carlton, T Chen, AL Whitcombe, R McGregor, G Scheurich, CR Sheen, ... Epidemiology & Infection 149, e173, 2021 | 9 | 2021 |
