| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 8 (4), 445-544, 2012 | 13110* | 2012 |
| Acetylated microtubules are required for fusion of autophagosomes with lysosomes R Xie, S Nguyen, WL McKeehan, L Liu BMC cell biology 11, 1-12, 2010 | 240 | 2010 |
| Spermidine prolongs lifespan and prevents liver fibrosis and hepatocellular carcinoma by activating MAP1S-mediated autophagy F Yue, W Li, J Zou, X Jiang, G Xu, H Huang, L Liu Cancer research 77 (11), 2938-2951, 2017 | 151 | 2017 |
| Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation R Xie, S Nguyen, K McKeehan, F Wang, WL McKeehan, L Liu Journal of Biological Chemistry 286 (12), 10367-10377, 2011 | 138 | 2011 |
| Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and … L Liu, WL McKeehan Genomics 79 (1), 124-136, 2002 | 101 | 2002 |
| High expression of CD147 and MMP-9 is correlated with poor prognosis of triple-negative breast cancer (TNBC) patients S Zhao, W Ma, M Zhang, D Tang, Q Shi, S Xu, X Zhang, Y Liu, Y Song, ... Medical Oncology 30, 1-8, 2013 | 98 | 2013 |
| FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity J Zhang, J Liu, Y Huang, JYF Chang, L Liu, WL McKeehan, JF Martin, ... Circulation research 110 (4), e29-e39, 2012 | 97 | 2012 |
| The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy J Zhang, J Liu, L Liu, WL McKeehan, F Wang Autophagy 8 (4), 690-691, 2012 | 78 | 2012 |
| Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis … L Liu, A Vo, G Liu, WL McKeehan In Vitro Cellular & Developmental Biology-Animal 38 (10), 582-594, 2002 | 75 | 2002 |
| Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5 L Liu, A Vo, WL McKeehan Cancer research 65 (5), 1830-1838, 2005 | 74 | 2005 |
| Autophagy enhanced by microtubule-and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis R Xie, F Wang, WL McKeehan, L Liu Cancer research 71 (24), 7537-7546, 2011 | 72 | 2011 |
| Distinct structural domains within C19ORF5 support association with stabilized microtubules and mitochondrial aggregation and genome destruction L Liu, A Vo, G Liu, WL McKeehan Cancer research 65 (10), 4191-4201, 2005 | 67 | 2005 |
| Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability J Zou, F Yue, X Jiang, W Li, J Yi, L Liu Biochemical Journal 454 (3), 447-457, 2013 | 58 | 2013 |
| Robust autophagy/mitophagy persists during mitosis L Liu, R Xie, S Nguyen, M Ye, WL McKeehan Cell Cycle 8 (10), 1616-1620, 2009 | 52 | 2009 |
| Spermidine confers liver protection by enhancing NRF2 signaling through a MAP1S-mediated non-canonical mechanism. ZDD Liu P, Vega MR, Dodson M, Yue F, Shi B, Fang D, Chapman E, Liu L Hepatology 70 (1), 372-388, 2019 | 50 | 2019 |
| Metastatic prostate cancer‐associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6 X Jiang, Y Huang, X Liang, F Jiang, Y He, T Li, G Xu, H Zhao, W Yang, ... The Prostate 78 (6), 426-434, 2018 | 49 | 2018 |
| Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival G Xu, Y Jiang, Y Xiao, XD Liu, F Yue, W Li, X Li, Y He, X Jiang, H Huang, ... Oncotarget 7 (5), 6255, 2016 | 49 | 2016 |
| Matrine suppresses invasion of castration-resistant prostate cancer cells by downregulating MMP-2/9 via NF-κB signaling pathway H Huang, T Du, G Xu, Y Lai, X Fan, X Chen, W Li, F Yue, Q Li, L Liu, K Li International Journal of Oncology 50 (2), 640-648, 2017 | 48 | 2017 |
| Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients X Jiang, W Zhong, H Huang, H He, F Jiang, Y Chen, F Yue, J Zou, X Li, ... Molecular carcinogenesis 54 (10), 1194-1204, 2015 | 48 | 2015 |
| Elevated levels of mitochondrion‐associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer X Jiang, X Li, H Huang, F Jiang, Z Lin, H He, Y Chen, F Yue, J Zou, Y He, ... Cancer 120 (8), 1228-1236, 2014 | 47 | 2014 |
Bradley W DobleAssociate Professor, University of ManitobaVerified email at umanitoba.ca
