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chris bahl
chris bahl
AI Proteins Inc, Boston Children's Hospital, Harvard Medical School
Verified email at aiproteins.bio - Homepage
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Cited by
Cited by
Year
Massively parallel de novo protein design for targeted therapeutics
A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ...
Nature 550 (7674), 74-79, 2017
4152017
Accurate de novo design of hyperstable constrained peptides
G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ...
Nature 538 (7625), 329-335, 2016
3842016
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, ...
Nature communications 12 (1), 1334, 2021
1032021
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators
BA Flitter, KL Hvorecny, E Ono, T Eddens, J Yang, DH Kwak, CD Bahl, ...
Proceedings of the national academy of sciences 114 (1), 136-141, 2017
762017
Screening, large-scale production and structure-based classification of cystine-dense peptides
CE Correnti, MM Gewe, C Mehlin, AD Bandaranayake, WA Johnsen, ...
Nature structural & molecular biology 25 (3), 270-278, 2018
532018
Discovery and engineering of enhanced SUMO protease enzymes
YTK Lau, V Baytshtok, TA Howard, BM Fiala, JLM Johnson, LP Carter, ...
Journal of Biological Chemistry 293 (34), 13224-13233, 2018
492018
Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor
CD Bahl, C Morisseau, JM Bomberger, BA Stanton, BD Hammock, ...
Journal of bacteriology 192 (7), 1785-1795, 2010
472010
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop
JF Amacher, PR Cushing, CD Bahl, T Beck, DR Madden
Journal of Biological Chemistry 288 (7), 5114-5126, 2013
392013
Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair
C D Bahl, D R Madden
Protein and peptide letters 19 (2), 186-193, 2012
302012
Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity
CD Bahl, KL Hvorecny, AA Bridges, AE Ballok, JM Bomberger, KC Cady, ...
Journal of Biological Chemistry 289 (11), 7460-7469, 2014
262014
An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung
KL Hvorecny, E Dolben, S Moreau-Marquis, TH Hampton, TB Shabaneh, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (1 …, 2018
232018
Inhibiting an epoxide hydrolase virulence factor from Pseudomonas aeruginosa protects CFTR
CD Bahl, KL Hvorecny, JM Bomberger, BA Stanton, BD Hammock, ...
Angewandte Chemie International Edition 54 (34), 9881-9885, 2015
222015
Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa
AE Ballok, CD Bahl, EL Dolben, AK Lindsay, JD St. Laurent, DA Hogan, ...
Journal of bacteriology 194 (19), 5315-5324, 2012
222012
Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa
CD Bahl, DP MacEachran, GA O'Toole, DR Madden
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
222010
Active-site flexibility and substrate specificity in a bacterial virulence factor: crystallographic snapshots of an epoxide hydrolase
KL Hvorecny, CD Bahl, S Kitamura, KSS Lee, BD Hammock, C Morisseau, ...
Structure 25 (5), 697-707. e4, 2017
162017
Visualizing the mechanism of epoxide hydrolysis by the bacterial virulence enzyme Cif
CD Bahl, KL Hvorecny, C Morisseau, SA Gerber, DR Madden
Biochemistry 55 (5), 788-797, 2016
162016
Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks
J Koehler Leman, S Lyskov, SM Lewis, J Adolf-Bryfogle, RF Alford, ...
Nature communications 12 (1), 6947, 2021
152021
Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design
J Adolf-Bryfogle, JW Labonte, JC Kraft, M Shapovalov, S Raemisch, ...
Biorxiv, 2021.09. 27.462000, 2021
152021
Two common structural motifs for TCR recognition by staphylococcal enterotoxins
KEJ Rödström, P Regenthal, C Bahl, A Ford, D Baker, ...
Scientific Reports 6 (1), 25796, 2016
152016
Toward complete rational control over protein structure and function through computational design
J Adolf-Bryfogle, FD Teets, CD Bahl
Current opinion in structural biology 66, 170-177, 2021
132021
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