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David Kroeger
David Kroeger
Associate Director BD, Zymeworks Inc.
Verified email at usask.ca
Title
Cited by
Cited by
Year
Tumor-infiltrating plasma cells are associated with tertiary lymphoid structures, cytolytic T-cell responses, and superior prognosis in ovarian cancer
DR Kroeger, K Milne, BH Nelson
Clinical Cancer Research 22 (12), 3005-3015, 2016
4592016
PD-L1 expression is associated with tumor-infiltrating T cells and favorable prognosis in high-grade serous ovarian cancer
JR Webb, K Milne, DR Kroeger, BH Nelson
Gynecologic oncology 141 (2), 293-302, 2016
3242016
Interfaces of malignant and immunologic clonal dynamics in ovarian cancer
AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ...
Cell 173 (7), 1755-1769. e22, 2018
2982018
Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer
DA Wick, JR Webb, JS Nielsen, SD Martin, DR Kroeger, K Milne, ...
Clinical Cancer Research 20 (5), 1125-1134, 2014
1712014
Neoadjuvant chemotherapy of ovarian cancer results in three patterns of tumor-infiltrating lymphocyte response with distinct implications for immunotherapy
CS Lo, S Sanii, DR Kroeger, K Milne, A Talhouk, DS Chiu, K Rahimi, ...
Clinical Cancer Research 23 (4), 925-934, 2017
1612017
Low mutation burden in ovarian cancer may limit the utility of neoantigen-targeted vaccines
SD Martin, SD Brown, DA Wick, JS Nielsen, DR Kroeger, ...
PloS one 11 (5), e0155189, 2016
1402016
CD25 Identifies a Subset of CD4+FoxP3 TIL That Are Exhausted Yet Prognostically Favorable in Human Ovarian Cancer
RJ deLeeuw, DR Kroeger, SE Kost, PP Chang, JR Webb, BH Nelson
Cancer immunology research 3 (3), 245-253, 2015
552015
Toward Personalized Lymphoma Immunotherapy: Identification of Common Driver Mutations Recognized by Patient CD8+ T Cells
JS Nielsen, CG Sedgwick, A Shahid, Z Zong, ZL Brumme, S Yu, L Liu, ...
Clinical Cancer Research 22 (9), 2226-2236, 2016
352016
The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions
CD Rudulier, KK McKinstry, GA Al-Yassin, DR Kroeger, PA Bretscher
The Journal of Immunology 192 (11), 5140-5150, 2014
302014
Antigen presenting B cells facilitate CD4 T cell cooperation resulting in enhanced generation of effector and memory CD4 T cells
DR Kroeger, CD Rudulier, PA Bretscher
PLoS One 8 (10), e77346, 2013
282013
CD4 T cell cooperation is required for the in vivo activation of CD4 T cells
NC Peters, DR Kroeger, S Mickelwright, PA Bretscher
International immunology 21 (11), 1213-1224, 2009
212009
Macroimmunology and immunotherapy of cancer
D Hamilton, N Ismail, D Kroeger, C Rudulier, P Bretscher
Immunotherapy 1 (3), 367-383, 2009
112009
Direct demonstration of CD4 T cell cooperation in the primary in vivo generation of CD4 effector T cells
DR Kroeger, CD Rudulier, NC Peters, PA Bretscher
International immunology 24 (8), 519-527, 2012
102012
Distinct roles of dendritic and B cells in the activation of naive CD4+ T cells
CD Rudulier, DR Kroeger, PA Bretscher
Immunotherapy 4 (4), 355-357, 2012
92012
Immune Outposts on the Inflammatory Frontier: Tertiary Lymphoid Structures as Targets for Immunotherapy of Cancer and Autoimmunity
K Silina, D Kroeger
Frontiers in immunology 10, 464208, 2019
32019
The activation, by antigen, of naïve TCR transgenic CD4 T cells cultured at physiological, rather than artificially high, frequencies more accurately reflects the in vivo …
CD Rudulier, DR Kroeger, PA Bretscher
Cellular immunology 274 (1-2), 115-120, 2012
32012
The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer
AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ...
bioRxiv, 198101, 2017
22017
Recombinant oncolytic viruses and uses thereof
B Nelson, K Twumasl-boateng, D Kroeger, P Chapani, D Peacock
US Patent App. 15/574,685, 2018
2018
Properties of the immune microenvironment associated with clonal diversity in high-grade serous ovarian cancer
AW Zhang, A McPherson, A Roth, DR Kroeger, K Milne, WW Wasserman, ...
Cancer Research 76 (14_Supplement), 4136-4136, 2016
2016
Mechanisms and Functional Consequences of CD4 T Cell Cooperation
D Kroeger
University of Saskatchewan, 2012
2012
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