High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ... Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014 | 403 | 2014 |
Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes MD Hall, KA Telma, KE Chang, TD Lee, JP Madigan, JR Lloyd, ... Cancer research 74 (14), 3913-3922, 2014 | 350 | 2014 |
Synthetic riboswitches that induce gene expression in diverse bacterial species S Topp, CMK Reynoso, JC Seeliger, IS Goldlust, SK Desai, D Murat, ... Applied and environmental microbiology 76 (23), 7881-7884, 2010 | 207 | 2010 |
An automated fitting procedure and software for dose-response curves with multiphasic features. GY Veroli, C Fornari, I Goldlust, G Mills, SB Koh, JL Bramhall, ... Scientific reports 5, 14701-14701, 2015 | 184 | 2015 |
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency T Wang, H Wu, Y Li, KE Szulwach, L Lin, X Li, IP Chen, IS Goldlust, ... Nature cell biology 15 (6), 700-711, 2013 | 107 | 2013 |
Mouse model implicates GNB3 duplication in a childhood obesity syndrome IS Goldlust, KE Hermetz, LM Catalano, RT Barfield, R Cozad, G Wynn, ... Proceedings of the National Academy of Sciences 110 (37), 14990-14994, 2013 | 39 | 2013 |
Density matters: comparison of array platforms for detection of copy-number variation and copy-neutral abnormalities H Mason-Suares, W Kim, L Grimmett, ES Williams, VL Horner, D Kunig, ... Genetics in Medicine 15 (9), 706-712, 2013 | 34 | 2013 |
Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest N Acquavella, D Clever, Z Yu, M Roelke-Parker, DC Palmer, L Xi, ... Cancer immunology research 3 (1), 37-47, 2015 | 32 | 2015 |
Large-scale pharmacological profiling of 3D tumor models of cancer cells LA Mathews Griner, X Zhang, R Guha, C McKnight, IS Goldlust, ... Cell death & disease 7 (12), e2492-e2492, 2016 | 31 | 2016 |
Drugs targeting tumor-initiating cells prolong survival in a post-surgery, post-chemotherapy ovarian cancer relapse model BS Harrington, MK Ozaki, MW Caminear, LF Hernandez, E Jordan, ... Cancers 12 (6), 1645, 2020 | 28 | 2020 |
Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy RC Jackson, GY Di Veroli, SB Koh, I Goldlust, FM Richards, DI Jodrell PLoS computational biology 13 (5), e1005529, 2017 | 15 | 2017 |
Loss of compensatory pro-survival and anti-apoptotic modulator, IKKε, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21 MK Kim, DJ Min, G Wright, I Goldlust, CM Annunziata Oncotarget 5 (24), 12788, 2014 | 15 | 2014 |
mQC: a heuristic quality-control metric for high-throughput drug combination screening L Chen, K Wilson, I Goldlust, BT Mott, R Eastman, MI Davis, X Zhang, ... Scientific Reports 6 (1), 37741, 2016 | 9 | 2016 |
Matrix drug screen identifies synergistic drug combinations to augment smac mimetic activity in ovarian cancer AM Noonan, A Cousins, D Anderson, KP Zeligs, K Bunch, L Hernandez, ... Cancers 12 (12), 3784, 2020 | 4 | 2020 |
Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species (vol 76, pg 7881, 2010) S Topp, CMK Reynoso, JC Seeliger, IS Goldlust, SK Desai, D Murat, ... Applied and Environmental Microbiology 77 (6), 2199-2199, 2011 | 2 | 2011 |
No cell left behind: Residual ovarian spheroids drive recurrence and are sensitive to the pro-oxidant elesclomol IS Goldlust, K Wilson, L Szabova, X Zhang, L Mathews-Griner, M Vias, ... Cancer Research 76 (14_Supplement), 278-278, 2016 | 1 | 2016 |
PARP inhibitors in ovarian cancer IS Goldlust, E Guidice, J Lee Seminars in Oncology, 2024 | | 2024 |
The spectrum of cell death in sarcoma E Belyaeva, N Loginova, BA Schroeder, IS Goldlust, A Acharya, S Kumar, ... Biomedicine & Pharmacotherapy 162, 114683, 2023 | | 2023 |
The Design of Theophylline Sensing Riboswitches in Agrobacteriumtumefaciens and Their Application in Reprogramming theVirA/VirG Two-Component System IS Goldlust | | 2009 |