Cytosolic proteostasis through importing of misfolded proteins into mitochondria L Ruan, C Zhou, E Jin, A Kucharavy, Y Zhang, Z Wen, L Florens, R Li Nature 543 (7645), 443-446, 2017 | 427 | 2017 |
Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells JM Perry, F Tao, A Roy, T Lin, XC He, S Chen, X Lu, J Nemechek, L Ruan, ... Nature cell biology 22 (6), 689-700, 2020 | 103 | 2020 |
An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution L Zhu, M Xu, M Yang, Y Yang, Y Li, J Deng, L Ruan, J Liu, S Du, X Liu, ... Human molecular genetics 23 (25), 6863-6877, 2014 | 62 | 2014 |
Mitochondria-associated proteostasis L Ruan, Y Wang, X Zhang, A Tomaszewski, JT McNamara, R Li Annual review of biophysics 49, 41-67, 2020 | 59 | 2020 |
Recent insights into the cellular and molecular determinants of aging L Ruan, X Zhang, R Li Journal of cell science 131 (3), jcs210831, 2018 | 27 | 2018 |
Solid-phase inclusion as a mechanism for regulating unfolded proteins in the mitochondrial matrix L Ruan, JT McNamara, X Zhang, ACC Chang, J Zhu, Y Dong, G Sun, ... Science Advances 6 (32), eabc7288, 2020 | 14 | 2020 |
Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications Nitika, B Zheng, L Ruan, JT Kline, S Omkar, J Sikora, M Texeira Torres, ... PLoS biology 20 (10), e3001839, 2022 | 10 | 2022 |
Metabolic regulation of misfolded protein import into mitochondria Y Wang, L Ruan, J Zhu, X Zhang, ACC Chang, A Tomaszewski, R Li bioRxiv, 2023 | 6 | 2023 |
A novel multifunctional role for Hsp70 in binding post-translational modifications on client proteins Nitika, B Zheng, L Ruan, JT Kline, J Sikora, MT Torres, Y Wang, ... BioRxiv, 2021.08. 25.457671, 2021 | 2 | 2021 |
GPI-anchored Gas1 protein regulates cytosolic proteostasis in budding yeast Y Wang, L Ruan, R Li G3: Genes, Genomes, Genetics, jkad263, 2024 | 1 | 2024 |
Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling Y Dong, BA Johnson, L Ruan, M Zeineldin, T Bi, AZ Liu, S Raychaudhuri, ... Science Advances 10 (14), eadj7666, 2024 | | 2024 |
GPI-anchored Gas1 protein regulates cytosolic proteostasis in yeast Y Wang, L Ruan, R Li bioRxiv, 2023 | | 2023 |