Discovery of a potent and selective small molecule hGPR91 antagonist D Bhuniya, D Umrani, B Dave, D Salunke, G Kukreja, J Gundu, M Naykodi, ... Bioorganic & medicinal chemistry letters 21 (12), 3596-3602, 2011 | 81 | 2011 |
Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats DN Umrani, AA Banday, T Hussain, MF Lokhandwala Hypertension 40 (6), 880-885, 2002 | 59 | 2002 |
Increased Renal Angiotensin II AT1 Receptor Function in Obese Zucker Rat M Becker, D Umrani, MF Lokhandwala, T Hussain Clinical and Experimental Hypertension 25 (1), 35-47, 2003 | 53 | 2003 |
Beneficial effects of fenoldopam treatment on renal function in streptozotocin-induced diabetic rats DN Umrani, RK Goyal Clinical and experimental hypertension 24 (3), 207-219, 2002 | 33 | 2002 |
Pharmacology of sildenafil citrate DN Umrani, RK Goyal Indian journal of physiology and pharmacology 43, 160-164, 1999 | 33 | 1999 |
Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia AM Deshpande, D Bhuniya, S De, B Dave, VP Vyavahare, SH Kurhade, ... European journal of medicinal chemistry 133, 268-286, 2017 | 21 | 2017 |
Fenoldopam treatment improves peripheral insulin sensitivity and renal function in STZ‐induced type 2 diabetic rats DN Umrani, RK Goyal Clinical and Experimental Hypertension 25 (4), 221-233, 2003 | 20 | 2003 |
Effect of chronic treatment with losartan on streptozotocin-induced renal dysfunction B Murali, DN Umrani, RK Goyal Molecular and cellular biochemistry 249, 85-90, 2003 | 17 | 2003 |
First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug Clinical Translational Science 13 (1), 57-66, 2020 | 12 | 2020 |
Effect of sarpogrelate on altered STZ-diabetes induced cardiovascular responses to 5-hydroxytryptamine in rats DN Umrani, DN Bodiwala, RK Goyal Biochemistry of Diabetes and Atherosclerosis, 53-57, 2003 | 12 | 2003 |
Phase I extension study of ETC-159 an oral PORCN inhibitor administered with bone protective treatment, in patients with advanced solid tumours D Tan, M Ng, V Subbiah, W Messersmith, V Teneggi, V Diermayr, ... Annals of Oncology 29, ix23-ix24, 2018 | 11 | 2018 |
An overview of pathophysiology and treatment of insulin resistance DN Umrani, RK Goyal Indian Journal of Physiology and Pharmacology 45 (1), 22-36, 2001 | 11 | 2001 |
Effect of parthenolide, an NLRP3 inflammasome inhibitor, on insulin resistance in high-fat diet-obese mice PK Chinta, S Tambe, D Umrani, AK Pal, M Nandave Canadian Journal of Physiology and Pharmacology 100 (3), 272-281, 2022 | 9 | 2022 |
Usefulness of 5-Ht2a Receptor Antagonists for The Treatment of Cardiovascular Complications in Diabetes RK Goyal, DN Umrani, DN Bodiwala, NS Dhalla Atherosclerosis, hypertension and diabetes, 317-326, 2003 | 8 | 2003 |
The Liver-Directed/Pancreas-Sparing Pharmacokinetic Profile of GKM-001, a Glucokinase Modulator With Robust Glucose Lowering Properties and Low Hypoglycemia Risk KA Mookhtiar, D Umrani, S De, D Bhuniya Diabetes 61, A291-A291, 2012 | 6 | 2012 |
Discovery and pharmacological evaluation of indole derivatives as potent and selective RORγt inverse agonist for multiple autoimmune conditions NS Shaikh, JP Iyer, YS Munot, PP Mukhopadhyay, AA Raje, R Nagaraj, ... Bioorganic & Medicinal Chemistry Letters 29 (16), 2208-2217, 2019 | 5 | 2019 |
Discovery and evaluation of 1H-pyrrolo [2, 3-b] pyridine based selective and reversible small molecule BTK inhibitors for the treatment of rheumatoid arthritis M Thakkar, D Bhuniya, R Kaduskar, T Mengawade, K Naik, V Salunkhe, ... Bioorganic & Medicinal Chemistry Letters 27 (8), 1867-1873, 2017 | 5 | 2017 |
Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors RK Banerjee, RC Gupta, D Tuli, M Rode, B Suthar, D Umrani, P Pathak, ... US Patent App. 11/992,016, 2009 | 5 | 2009 |
GKM-001, a Glucokinase Modulator With Liver-Directed/Pancreas-Sparing Action Improves Glucose Control in Rodent Models of Diabetes Without Hypoglycemia Risk or Tachyphylaxis KA Mookhtiar, D Umrani, S Tambe, P Shitole, V Kothari, A Deshpande, ... Diabetes 61, A252-A253, 2012 | 2 | 2012 |
Effect of sarpogrelate on altered 5-hydroxytryptamine-induced responses in STZ-diabetic rats DN Umrani, RK Goyal Journal of Molecular and Cellular Cardiology 6 (33), A124, 2001 | 2 | 2001 |