| Triglyceride accumulation protects against fatty acid-induced lipotoxicity LL Listenberger, X Han, SE Lewis, S Cases, RV Farese Jr, DS Ory, ... Proceedings of the National Academy of Sciences 100 (6), 3077-3082, 2003 | 2174 | 2003 |
| Lipotoxicity: when tissues overeat JE Schaffer Current opinion in lipidology 14 (3), 281-287, 2003 | 1212 | 2003 |
| Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein JE Schaffer, HF Lodish Cell 79 (3), 427-436, 1994 | 1094 | 1994 |
| A novel mouse model of lipotoxic cardiomyopathy HC Chiu, A Kovacs, DA Ford, FF Hsu, R Garcia, P Herrero, JE Saffitz, ... The Journal of clinical investigation 107 (7), 813-822, 2001 | 901 | 2001 |
| Palmitate-induced apoptosis can occur through a ceramide-independent pathway LL Listenberger, DS Ory, JE Schaffer Journal of Biological Chemistry 276 (18), 14890-14895, 2001 | 717 | 2001 |
| Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death NM Borradaile, X Han, JD Harp, SE Gale, DS Ory, JE Schaffer Journal of lipid research 47 (12), 2726-2737, 2006 | 668 | 2006 |
| Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy HC Chiu, A Kovacs, RM Blanton, X Han, M Courtois, CJ Weinheimer, ... Circulation research 96 (2), 225-233, 2005 | 537 | 2005 |
| Diet-induced obesity model: abnormal oocytes and persistent growth abnormalities in the offspring ES Jungheim, EL Schoeller, KL Marquard, ED Louden, JE Schaffer, ... Endocrinology 151 (8), 4039-4046, 2010 | 396 | 2010 |
| Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease FD Porter, DE Scherrer, MH Lanier, SJ Langmade, V Molugu, SE Gale, ... Science translational medicine 2 (56), 56ra81-56ra81, 2010 | 395 | 2010 |
| As a matter of fat RT Brookheart, CI Michel, JE Schaffer Cell metabolism 10 (1), 9-12, 2009 | 329 | 2009 |
| Cloning, Sequencing, and Functional Analysis of oriL, a Herpes Simplex Virus Type 1 Origin of DNA Synthesis SK Weller, A Spadaro, JE Schaffer, AW Murray, AM Maxam, PA Schaffer Molecular and Cellular Biology 5 (5), 930-942, 1985 | 312 | 1985 |
| A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [S] X Jiang, R Sidhu, FD Porter, NM Yanjanin, AO Speak, DT Te Vruchte, ... Journal of lipid research 52 (7), 1435-1445, 2011 | 304 | 2011 |
| Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system SC Souza, KV Muliro, L Liscum, P Lien, MT Yamamoto, JE Schaffer, ... Journal of Biological Chemistry 277 (10), 8267-8272, 2002 | 289 | 2002 |
| DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity L Liu, XJ Shi, KG Bharadwaj, S Ikeda, H Yamashita, H Yagyu, JE Schaffer, ... Journal of biological chemistry 284 (52), 36312-36323, 2009 | 273 | 2009 |
| NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols A Frolov, SE Zielinski, JR Crowley, N Dudley-Rucker, JE Schaffer, DS Ory Journal of Biological Chemistry 278 (28), 25517-25525, 2003 | 263 | 2003 |
| Mitochondrial reactive oxygen species in lipotoxic hearts induce post-translational modifications of AKAP121, DRP1, and OPA1 that promote mitochondrial fission K Tsushima, H Bugger, AR Wende, J Soto, GA Jenson, AR Tor, ... Circulation research 122 (1), 58-73, 2018 | 256 | 2018 |
| Fatty acid transport: the roads taken JE Schaffer American Journal of Physiology-Endocrinology and Metabolism 282 (2), E239-E246, 2002 | 253 | 2002 |
| Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress CI Michel, CL Holley, BS Scruggs, R Sidhu, RT Brookheart, ... Cell metabolism 14 (1), 33-44, 2011 | 250 | 2011 |
| Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding ME Gelsthorpe, N Baumann, E Millard, SE Gale, SJ Langmade, ... Journal of Biological Chemistry 283 (13), 8229-8236, 2008 | 215 | 2008 |
| Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane CE Gargiulo, SM Stuhlsatz-Krouper, JE Schaffer Journal of lipid research 40 (5), 881-892, 1999 | 192 | 1999 |
