| NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function TR Alderson, LE Kay Cell 184 (3), 577-595, 2021 | 118 | 2021 |
| Dynamical structures of Hsp70 and Hsp70-Hsp40 complexes TR Alderson, JH Kim, JL Markley Structure 24 (7), 1014-1030, 2016 | 115 | 2016 |
| Local unfolding of the HSP27 monomer regulates chaperone activity TR Alderson, J Roche, HY Gastall, DM Dias, I Pritišanac, J Ying, A Bax, ... Nature Communications 10 (1), 1068, 2019 | 99 | 2019 |
| Biophysical characterization of α-synuclein and its controversial structure TR Alderson, JL Markley Intrinsically Disordered Proteins 1 (1), e26255, 2013 | 99 | 2013 |
| Unveiling invisible protein states with NMR spectroscopy TR Alderson, LE Kay Current Opinion in Structural Biology 60, 39-49, 2020 | 89 | 2020 |
| Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell C Charlier, TR Alderson, JM Courtney, J Ying, P Anfinrud, A Bax Proceedings of the National Academy of Sciences 115 (18), E4169-E4178, 2018 | 72 | 2018 |
| Propensity for cis-proline formation in unfolded proteins TR Alderson, JH Lee, C Charlier, J Ying, A Bax ChemBioChem 19 (1), 37, 2018 | 69 | 2018 |
| Automatic assignment of methyl-NMR spectra of supramolecular machines using graph theory I Pritisanac, MT Degiacomi, TR Alderson, MG Carneiro, E Ab, G Siegal, ... Journal of the American Chemical Society 139 (28), 9523-9533, 2017 | 60 | 2017 |
| Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2 TR Alderson#, I Pritišanac#, Đ Kolarić, AM Moses, JD Forman-Kay Proceedings of the National Academy of Sciences 120 (44), e2304302120, 2023 | 58* | 2023 |
| HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C MP Collier, TR Alderson, CP de Villiers, D Nicholls, HY Gastall, TM Allison, ... Science Advances 5 (5), eaav8421, 2019 | 56 | 2019 |
| Tangled web of interactions among proteins involved in iron–sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies JH Kim, JR Bothe, TR Alderson, JL Markley Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (6), 1416-1428, 2015 | 48 | 2015 |
| Automatic structure-based NMR methyl resonance assignment in large proteins I Pritišanac, JM Würz, TR Alderson, P Güntert Nature Communications 10, 4922, 2019 | 38 | 2019 |
| Monitoring hydrogen exchange during protein folding by fast pressure jump NMR spectroscopy TR Alderson*, C Charlier*, DA Torchia, P Anfinrud, A Bax Journal of the American Chemical Society 139 (32), 11036-11039, 2017 | 34 | 2017 |
| The Specialized Hsp70 (HscA) Interdomain Linker Binds to Its Nucleotide-Binding Domain and Stimulates ATP Hydrolysis in Both cis and trans Configurations TR Alderson, JH Kim, K Cai, RO Frederick, M Tonelli, JL Markley Biochemistry 53 (46), 7148-7159, 2014 | 32 | 2014 |
| Automated assignment of methyl NMR spectra from large proteins I Pritišanac, TR Alderson, P Güntert Progress in Nuclear Magnetic Resonance Spectroscopy 118, 54-73, 2020 | 31 | 2020 |
| Proline isomerization in the C-terminal region of HSP27 TR Alderson, JLP Benesch, AJ Baldwin Cell Stress and Chaperones 22 (4), 639-651, 2017 | 31 | 2017 |
| Nucleotide-dependent interactions within a specialized Hsp70/Hsp40 complex involved in Fe–S cluster biogenesis JH Kim, TR Alderson, RO Frederick, JL Markley Journal of the American Chemical Society 136 (33), 11586-11589, 2014 | 30 | 2014 |
| Conditional disorder in small heat-shock proteins TR Alderson, J Ying, A Bax, JLP Benesch, AJ Baldwin Journal of Molecular Biology 432 (9), 3033-3049, 2020 | 24 | 2020 |
| Monitoring 15N Chemical Shifts During Protein Folding by Pressure-Jump NMR C Charlier, JM Courtney, TR Alderson, P Anfinrud, A Bax Journal of the American Chemical Society 140 (26), 8096-8099, 2018 | 21 | 2018 |
| A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins TR Alderson*, E Adriaenssens*, B Asselbergh, I Pritišanac, J Van Lent, ... The EMBO Journal, e103811, 2021 | 18* | 2021 |
Iva PritišanacPostdoctoral Fellow, The Hospital for Sick Children, TorontoVerified email at sickkids.ca
