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James D Thomas
James D Thomas
NIH/NCI K99/R00 Pathway to Independence Fellow
Verified email at fredhutch.org
Title
Cited by
Cited by
Year
Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9
R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ...
Cell 170 (5), 899-912. e10, 2017
2812017
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
SX Lu*, E De Neef*, JD Thomas*, E Sabio, B Rousseau, M Gigoux, ...
Cell doi: 10.1016/j.cell.2021.05.038 (*equal contribution), 2021
1512021
Intron retention induced by microsatellite expansions as a disease biomarker
ŁJ Sznajder*, JD Thomas*, EM Carrell, T Reid, KN McFarland, JD Cleary, ...
Proceedings of the National Academy of Sciences 115 (16), 4234-4239 (*equal …, 2018
1012018
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy
JD Thomas, ŁJ Sznajder, O Bardhi, FN Aslam, ZP Anastasiadis, MM Scotti, ...
Genes & development 31 (11), 1122-1133, 2017
912017
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons
JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ...
Nature genetics 52 (1), 84-94, 2020
802020
Discovery of synthetic lethal and tumor suppressive paralog pairs in the human genome
PCR Parrish*, JD Thomas*, S Kamlapurkar, A Gabel, RK Bradley, ...
Cell Reports 36, 109597 (*equal contribution), 2021
662021
European corn borer (Ostrinia nubilalis) induced responses enhance susceptibility in maize
NJ Dafoe, JD Thomas, PD Shirk, ME Legaspi, MM Vaughan, A Huffaker, ...
PLoS One 8 (9), e73394, 2013
592013
Arp2/3 and Mena/VASP require profilin 1 for actin network assembly at the leading edge
K Skruber, PV Warp, R Shklyarov, JD Thomas, MS Swanson, ...
Current Biology 30 (14), 2651-2664. e5, 2020
552020
Aberrant myokine signaling in congenital myotonic dystrophy
M Nakamori, K Hamanaka, JD Thomas, ET Wang, YK Hayashi, ...
Cell reports 21 (5), 1240-1252, 2017
462017
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy
MCG Iradi*, JC Triplett*, JD Thomas*, R Davila, AM Crown, H Brown, ...
Scientific reports 8 (1), 1-15 (*equal contribution), 2018
432018
The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1
R Batra, DA Nelles, DM Roth, F Krach, CA Nutter, T Tadokoro, JD Thomas, ...
Nature biomedical engineering 5 (2), 157-168, 2021
402021
Myotonic dystrophy and developmental regulation of RNA processing
JD Thomas, O Ruan, ŁJ Sznajder, MS Swanson
Comprehensive physiology 8 (2), 509-553, 2018
39*2018
MBNL splicing activity depends on RNA binding site structural context
K Taylor, ŁJ Sznajder, P Cywoniuk, JD Thomas, MS Swanson, K Sobczak
Nucleic acids research 46 (17), 9119-9133, 2018
372018
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells
K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ...
Nature biotechnology 40 (7), 1103-1113, 2022
352022
HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy
M Li, Y Zhuang, R Batra, JD Thomas, M Li, CA Nutter, MM Scotti, ...
Proceedings of the National Academy of Sciences 117 (10), 5472-5477, 2020
352020
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
A Vichas, AK Riley, NT Nkinsi, S Kamlapurkar, PCR Parrish, A Lo, F Duke, ...
Nature communications 12 (1), 4789, 2021
262021
RBPMetaDB: a comprehensive annotation of mouse RNA-Seq datasets with perturbations of RNA-binding proteins
J Li, SP Deng, J Vieira, J Thomas, V Costa, CS Tseng, F Ivankovic, ...
Database 2018, bay054, 2018
42018
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo
AM Gabel, AE Belleville, JD Thomas, SA McKellar, TR Nicholas, T Banjo, ...
Nature Communications 15 (1), 959, 2024
2024
pgMAP: a pipeline to enable guide RNA read mapping from dual-targeting CRISPR screens
PCR Parrish, DJ Groso, JD Thomas, RK Bradley, AH Berger
ArXiv, 2023
2023
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Articles 1–19