| A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy Q Feng, L Snider, S Jagannathan, R Tawil, SM van der Maarel, ... elife 4, e04996, 2015 | 123 | 2015 |
| How to get away with nonsense: Mechanisms and consequences of escape from nonsense‐mediated RNA decay MC Dyle, D Kolakada, MA Cortazar, S Jagannathan Wiley Interdisciplinary Reviews: RNA 11 (1), e1560, 2020 | 105 | 2020 |
| Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells S Jagannathan, SC Shadle, R Resnick, L Snider, RN Tawil, ... Human Molecular Genetics 25 (20), 4419-4431, 2016 | 101 | 2016 |
| DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy SC Shadle, JW Zhong, AE Campbell, ML Conerly, S Jagannathan, ... PLoS Genetics 13 (3), e1006658, 2017 | 99 | 2017 |
| Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells Q Chen, S Jagannathan, DW Reid, T Zheng, CV Nicchitta Molecular biology of the cell 22 (14), 2646-2658, 2011 | 87 | 2011 |
| Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation S Jagannathan, C Nwosu, CV Nicchitta RNA Detection and Visualization: Methods and Protocols, 301-321, 2011 | 70 | 2011 |
| De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum S Jagannathan, DW Reid, AH Cox, CV Nicchitta Rna 20 (10), 1489-1498, 2014 | 65 | 2014 |
| NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins AE Campbell, SC Shadle, S Jagannathan, JW Lim, R Resnick, R Tawil, ... Elife 7, e31023, 2018 | 62 | 2018 |
| The RNA surveillance factor UPF1 represses myogenesis via its E3 ubiquitin ligase activity Q Feng, S Jagannathan, RK Bradley Molecular cell 67 (2), 239-251. e6, 2017 | 58 | 2017 |
| Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum S Jagannathan, JCC Hsu, DW Reid, Q Chen, WJ Thompson, AM Moseley, ... Journal of Biological Chemistry 289 (37), 25907-25924, 2014 | 56 | 2014 |
| Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy S Jagannathan, Y Ogata, PR Gafken, SJ Tapscott, RK Bradley Elife 8, e41740, 2019 | 38 | 2019 |
| Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population S Jagannathan, RK Bradley Genome Research 26 (12), 1639-1650, 2016 | 37 | 2016 |
| Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules JR Child, Q Chen, DW Reid, S Jagannathan, CV Nicchitta Rna 27 (10), 1241-1256, 2021 | 29 | 2021 |
| Premature translational termination products are rapidly degraded substrates for MHC class I presentation JR Lacsina, OA Marks, X Liu, DW Reid, S Jagannathan, CV Nicchitta PloS one 7 (12), e51968, 2012 | 19 | 2012 |
| Meeting report: the 2021 FSHD international research congress S Jagannathan, JC de Greef, LJ Hayward, K Yokomori, D Gabellini, K Mul, ... Skeletal Muscle 12 (1), 1, 2022 | 16 | 2022 |
| Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression AE Campbell, MC Dyle, R Albanese, T Matheny, K Sudheendran, ... Cell reports 42 (6), 2023 | 12* | 2023 |
| Principles, mechanisms, and biological implications of translation termination–reinitiation ME Sherlock, LB Galvis, Q Vicens, JS Kieft, S Jagannathan RNA 29 (7), 865-884, 2023 | 9 | 2023 |
| The long and short of EJC-independent nonsense-mediated RNA decay O Muñoz, M Lore, S Jagannathan Biochemical Society Transactions 51 (3), 1121-1129, 2023 | 4 | 2023 |
| The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs DC Hamm, EM Paatela, SR Bennett, CJ Wong, AE Campbell, CL Wladyka, ... PLoS Biology 21 (9), e3002317, 2023 | 3 | 2023 |
| The evolution of DUX4 gene regulation and its implication for facioscapulohumeral muscular dystrophy S Jagannathan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (5), 166367, 2022 | 3 | 2022 |
Christopher NicchittaProfessor of Cell Biology and BiochemistryVerified email at duke.edu
