| Evolution and functional impact of rare coding variation from deep sequencing of human exomes JA Tennessen, AW Bigham, TD O’Connor, W Fu, EE Kenny, S Gravel, ... science 337 (6090), 64-69, 2012 | 1879 | 2012 |
| Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ... Nature 590 (7845), 290-299, 2021 | 1316 | 2021 |
| Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants W Fu, TD O’Connor, G Jun, HM Kang, G Abecasis, SM Leal, S Gabriel, ... Nature 493 (7431), 216, 2013 | 1185 | 2013 |
| Great ape genetic diversity and population history J Prado-Martinez, PH Sudmant, JM Kidd, H Li, JL Kelley, ... Nature 499 (7459), 471, 2013 | 931 | 2013 |
| Insights into hominid evolution from the gorilla genome sequence A Scally, JY Dutheil, LDW Hillier, GE Jordan, I Goodhead, J Herrero, ... Nature 483 (7388), 169, 2012 | 805 | 2012 |
| A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome RA Mathias, MA Taub, CR Gignoux, W Fu, S Musharoff, TD O'Connor, ... Nature communications 7 (1), 12522, 2016 | 157 | 2016 |
| Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire DN Harris, W Song, AC Shetty, KS Levano, O Cáceres, C Padilla, V Borda, ... Proceedings of the National Academy of Sciences 115 (28), E6526-E6535, 2018 | 143 | 2018 |
| Exome sequencing of Pakistani consanguineous families identifies 30 novel candidate genes for recessive intellectual disability S Riazuddin, M Hussain, A Razzaq, Z Iqbal, M Shahzad, DL Polla, Y Song, ... Molecular psychiatry 22 (11), 1604-1614, 2017 | 133 | 2017 |
| An integrated genomic and transcriptomic survey of mucormycosis-causing fungi MC Chibucos, S Soliman, T Gebremariam, H Lee, S Daugherty, J Orvis, ... Nature communications 7 (1), 12218, 2016 | 127 | 2016 |
| DNA reference alignment benchmarks based on tertiary structure of encoded proteins H Carroll, W Beckstead, T O'Connor, M Ebbert, M Clement, Q Snell, ... Bioinformatics 23 (19), 2648-2649, 2007 | 89 | 2007 |
| Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations M Daya, N Rafaels, TM Brunetti, S Chavan, AM Levin, A Shetty, ... Nature communications 10 (1), 880, 2019 | 87 | 2019 |
| Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry MD Kessler, L Yerges-Armstrong, MA Taub, AC Shetty, K Maloney, ... Nature communications 7 (1), 12521, 2016 | 75 | 2016 |
| De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population MD Kessler, DP Loesch, JA Perry, NL Heard-Costa, D Taliun, BE Cade, ... Proceedings of the National Academy of Sciences 117 (5), 2560-2569, 2020 | 66 | 2020 |
| Characterizing the genetic architecture of Parkinson's disease in Latinos DP Loesch, ARVR Horimoto, K Heilbron, EI Sarihan, M Inca‐Martinez, ... Annals of neurology 90 (3), 353-365, 2021 | 58 | 2021 |
| Genetic architecture of quantitative traits and complex diseases W Fu, T D O’Connor, JM Akey Current opinion in genetics & development 23 (6), 678-683, 2013 | 55 | 2013 |
| Evolution of hominin polyunsaturated fatty acid metabolism: from Africa to the New World DN Harris, I Ruczinski, LR Yanek, LC Becker, DM Becker, H Guio, T Cui, ... Genome biology and evolution 11 (5), 1417-1430, 2019 | 53 | 2019 |
| Population sequencing data reveal a compendium of mutational processes in the human germ line VB Seplyarskiy, RA Soldatov, E Koch, RJ McGinty, JM Goldmann, ... Science 373 (6558), 1030-1035, 2021 | 52 | 2021 |
| A positively selected FBN1 missense variant reduces height in Peruvian individuals S Asgari, Y Luo, A Akbari, GM Belbin, X Li, DN Harris, M Selig, E Bartell, ... Nature 582 (7811), 234-239, 2020 | 52 | 2020 |
| Rare variation facilitates inferences of fine-scale population structure in humans TD O’Connor, W Fu, NHLBI GO Exome Sequencing Project, ... Molecular Biology and Evolution 32 (3), 653-660, 2015 | 51 | 2015 |
| Fine-scale patterns of population stratification confound rare variant association tests TD O’Connor, A Kiezun, M Bamshad, SS Rich, JD Smith, E Turner, ... PloS one 8 (7), e65834, 2013 | 48 | 2013 |
Joshua AkeyProfessor of Ecology and Evolutionary Biology and Lewis Sigler Institute, Princeton UniversityVerified email at princeton.edu
