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Alexander J. Muller
Alexander J. Muller
Verified email at mlhs.org - Homepage
Title
Cited by
Cited by
Year
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
TG Lugo, AM Pendergast, AJ Muller, ON Witte
Science 247 (4946), 1079-1082, 1990
17631990
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
AJ Muller, JB DuHadaway, PS Donover, E Sutanto-Ward, GC Prendergast
Nature medicine 11 (3), 312-319, 2005
12412005
Inhibition of indoleamine 2, 3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses
DY Hou, AJ Muller, MD Sharma, J DuHadaway, T Banerjee, M Johnson, ...
Cancer research 67 (2), 792-801, 2007
7192007
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan
R Metz, JB DuHadaway, U Kamasani, L Laury-Kleintop, AJ Muller, ...
Cancer research 67 (15), 7082-7087, 2007
5852007
Indoleamine 2, 3‐dioxygenase in T‐cell tolerance and tumoral immune escape
JB Katz, AJ Muller, GC Prendergast
Immunological reviews 222 (1), 206-221, 2008
5162008
BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias
AJ Muller, JC Young, AM Pendergast, M Pondel, NR Landau, DR Littman, ...
Molecular and cellular biology 11 (4), 1785-1792, 1991
5081991
Discovery of IDO1 inhibitors: from bench to bedside
GC Prendergast, WP Malachowski, JB DuHadaway, AJ Muller
Cancer research 77 (24), 6795-6811, 2017
5052017
Indoleamine 2, 3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
GC Prendergast, C Smith, S Thomas, L Mandik-Nayak, L Laury-Kleintop, ...
Cancer immunology, immunotherapy 63, 721-735, 2014
5052014
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner
AM Pendergast, AJ Muller, MH Havlik, Y Maru, ON Witte
Cell 66 (1), 161-171, 1991
4981991
The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists
S Thomas, J Izard, E Walsh, K Batich, P Chongsathidkiet, G Clarke, ...
Cancer research 77 (8), 1783-1812, 2017
3642017
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
AJ Muller, PA Scherle
Nature Reviews Cancer 6 (8), 613-625, 2006
3412006
IDO is a nodal pathogenic driver of lung cancer and metastasis development
C Smith, MY Chang, KH Parker, DW Beury, JB DuHadaway, HE Flick, ...
Cancer discovery 2 (8), 722-735, 2012
335*2012
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2, 3 dioxygenase
AJ Muller, MD Sharma, PR Chandler, JB DuHadaway, ME Everhart, ...
Proceedings of the National Academy of Sciences 105 (44), 17073-17078, 2008
2822008
Indoleamine 2, 3-dioxygenase and its therapeutic inhibition in cancer
GC Prendergast, WJ Malachowski, A Mondal, P Scherle, AJ Muller
International review of cell and molecular biology 336, 175-203, 2018
2452018
Structure− activity study of brassinin derivatives as indoleamine 2, 3-dioxygenase inhibitors
P Gaspari, T Banerjee, WP Malachowski, AJ Muller, GC Prendergast, ...
Journal of medicinal chemistry 49 (2), 684-692, 2006
2292006
Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond
AJ Muller, MG Manfredi, Y Zakharia, GC Prendergast
Seminars in immunopathology 41, 41-48, 2019
2192019
Indoleamine 2, 3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors
S Kumar, WP Malachowski, JB DuHadaway, JM LaLonde, PJ Carroll, ...
Journal of medicinal chemistry 51 (6), 1706-1718, 2008
2092008
Indoleamine 2, 3-dioxygenase in immune suppression and cancer
AJ Muller, GC Prendergast
Current cancer drug targets 7 (1), 31-40, 2007
2052007
A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2, 3-dioxygenase
T Banerjee, JB Duhadaway, P Gaspari, E Sutanto-Ward, DH Munn, ...
Oncogene 27 (20), 2851-2857, 2008
2012008
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.
AM Pendergast, AJ Muller, MH Havlik, R Clark, F McCormick, ON Witte
Proceedings of the National Academy of Sciences 88 (13), 5927-5931, 1991
1991991
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