| Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3–E1 osteoblasts J You, GC Reilly, X Zhen, CE Yellowley, Q Chen, HJ Donahue, ... Journal of Biological Chemistry 276 (16), 13365-13371, 2001 | 500 | 2001 |
| Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow J You, CE Yellowley, HJ Donahue, Y Zhang, Q Chen, CR Jacobs J. Biomech. Eng. 122 (4), 387-393, 2000 | 442 | 2000 |
| The role of osteopontin in the progression of solid organ tumour H Zhao, Q Chen, A Alam, J Cui, KC Suen, AP Soo, S Eguchi, J Gu, D Ma Cell death & disease 9 (3), 1-15, 2018 | 288 | 2018 |
| Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell‐derived factor 1 and CXC chemokine receptor 4 K Kanbe, K Takagishi, Q Chen Arthritis & Rheumatism 46 (1), 130-137, 2002 | 258 | 2002 |
| Mechanoregulation of chondrocyte proliferation, maturation, and hypertrophy: ion-channel dependent transduction of matrix deformation signals Q Wu, Q Chen Experimental cell research 256 (2), 383-391, 2000 | 251 | 2000 |
| Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling W Yang, J Wang, DC Moore, H Liang, M Dooner, Q Wu, R Terek, Q Chen, ... Nature 499 (7459), 491-495, 2013 | 244 | 2013 |
| Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferation Q Wu, Y Zhang, Q Chen Journal of Biological Chemistry 276 (38), 35290-35296, 2001 | 237 | 2001 |
| Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation PS Vezeridis, CM Semeins, Q Chen, J Klein-Nulend Biochemical and biophysical research communications 348 (3), 1082-1088, 2006 | 220 | 2006 |
| miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4 J Li, J Huang, L Dai, D Yu, Q Chen, X Zhang, K Dai Arthritis research & therapy 14, 1-13, 2012 | 205 | 2012 |
| Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage F Wei, J Zhou, X Wei, J Zhang, BC Fleming, R Terek, M Pei, Q Chen, T Liu, ... Osteoarthritis and cartilage 20 (7), 755-763, 2012 | 177 | 2012 |
| Collagen types IX and X in the developing chick tibiotarsus: analyses of mRNAs and proteins TF Linsenmayer, Q Chen, E Gibney, MK Gordon, JK Marchant, R Mayne, ... Development 111 (1), 191-196, 1991 | 169 | 1991 |
| MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4 YJ Guan, X Yang, L Wei, Q Chen The FASEB Journal 25 (12), 4457, 2011 | 168 | 2011 |
| Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss H Li, D Li, Z Ma, Z Qian, X Kang, X Jin, F Li, X Wang, Q Chen, H Sun, ... Autophagy 14 (10), 1726-1741, 2018 | 161 | 2018 |
| Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis K Kanbe, T Takemura, K Takeuchi, Q Chen, K Takagishi, K Inoue The Journal of Bone & Joint Surgery British Volume 86 (2), 296-300, 2004 | 146 | 2004 |
| Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation Q Chen, DM Johnson, DR Haudenschild, PF Goetinck Developmental biology 172 (1), 293-306, 1995 | 143 | 1995 |
| Adipokines: new therapeutic target for osteoarthritis? C Xie, Q Chen Current rheumatology reports 21, 1-9, 2019 | 140 | 2019 |
| Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone X Zhen, L Wei, Q Wu, Y Zhang, Q Chen Journal of Biological Chemistry 276 (7), 4879-4885, 2001 | 135 | 2001 |
| Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis L van der Weyden, L Wei, J Luo, X Yang, DE Birk, DJ Adams, A Bradley, ... The American journal of pathology 169 (2), 515-527, 2006 | 124 | 2006 |
| CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression X Sun, L Wei, Q Chen, RM Terek Molecular Cancer 9, 1-11, 2010 | 113 | 2010 |
| Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreER T2; Ihh fl/fl mice J Zhou, Q Chen, B Lanske, BC Fleming, R Terek, X Wei, G Zhang, ... Arthritis research & therapy 16, 1-10, 2014 | 112 | 2014 |
Yingjie GuanAssistant Professor Brown UniversityVerified email at brown.edu
