Chebulagic acid, a COX–LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz., induces apoptosis in COLO-205 cell line DB Reddy, TCM Reddy, G Jyotsna, S Sharan, N Priya, V Lakshmipathi, ... Journal of ethnopharmacology 124 (3), 506-512, 2009 | 218 | 2009 |
Model‐based analysis of cannabidiol dose‐exposure relationship and bioavailability SY Lim, S Sharan, S Woo Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 40 (4 …, 2020 | 40 | 2020 |
Applications of physiologically based biopharmaceutics modeling (PBBM) to support drug product quality: a workshop summary report A Mitra, S Suarez-Sharp, XJH Pepin, T Flanagan, Y Zhao, E Kotzagiorgis, ... Journal of Pharmaceutical Sciences 110 (2), 594-609, 2021 | 36 | 2021 |
In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide S Sharan, OF Iwuchukwu, DJ Canney, CL Zimmerman, S Nagar Drug Metabolism and Disposition 40 (10), 1993-2001, 2012 | 24 | 2012 |
Analytical method development for synthesized conjugated metabolites of< i> trans</i>-resveratrol, and application to pharmacokinetic studies OF Iwuchukwu*, S Sharan*, DJ Canney, S Nagar Journal of Pharmaceutical and Biomedical Analysis, 2011 | 24 | 2011 |
Pulmonary metabolism of resveratrol: in vitro and in vivo evidence S Sharan, S Nagar Drug Metabolism and Disposition 41 (5), 1163-69, 2013 | 20 | 2013 |
“Target-site” drug metabolism and transport RS Foti, RF Tyndale, KLP Garcia, DH Sweet, S Nagar, S Sharan, DA Rock Drug Metabolism and Disposition 43 (8), 1156-1168, 2015 | 17 | 2015 |
Systems pharmacology approaches for optimization of antiangiogenic therapies: challenges and opportunities S Sharan, S Woo Frontiers in pharmacology 6, 117955, 2015 | 16 | 2015 |
Efficient model-based bioequivalence testing K Möllenhoff, F Loingeville, J Bertrand, TT Nguyen, S Sharan, L Zhao, ... Biostatistics 23 (1), 314-327, 2022 | 13 | 2022 |
Physiologically based pharmacokinetic and absorption modeling for osmotic pump products Z Ni, A Talattof, J Fan, E Tsakalozou, S Sharan, D Sun, H Wen, L Zhao, ... The AAPS Journal 19, 1045-1053, 2017 | 12 | 2017 |
Model‐Informed Drug Development for Long‐Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium. S Sharan, L Fang, V Lukacova, X Chen, AC Hooker, MO Karlsson Clinical Pharmacology in Drug Development 10 (3), 2021 | 10 | 2021 |
Quantitative Insight in Utilizing Circulating Angiogenic Factors as Biomarkers for Antiangiogenic Therapy: Systems Pharmacology Approach S Sharan, S Woo CPT: Pharmacometrics & Systems Pharmacology, 2014 | 9 | 2014 |
Use of partial area under the curve in bioavailability or bioequivalence assessments: a regulatory perspective L Fang, R Uppoor, M Xu, S Sharan, H Zhu, N Tampal, B Li, L Zhang, ... Clinical Pharmacology & Therapeutics 110 (4), 880-887, 2021 | 7 | 2021 |
New model–based bioequivalence statistical approaches for pharmacokinetic studies with sparse sampling F Loingeville, J Bertrand, TT Nguyen, S Sharan, K Feng, W Sun, J Han, ... The AAPS journal 22, 1-8, 2020 | 6 | 2020 |
Phase Ib clinical trial of OKN-007 in recurrent malignant glioma. JD Battiste, A Ikeguchi, S Woo, S Sharan, YD Zhao, A Cohoon, S Sung, ... Journal of Clinical Oncology 38 (15_suppl), 2538-2538, 2020 | 6 | 2020 |
An in vitro approach for evaluating the oral abuse deterrence of solid oral extended-release opioids with properties intended to deter abuse via chewing A Externbrink, S Sharan, D Sun, W Jiang, D Keire, X Xu International Journal of Pharmaceutics 561, 305-313, 2019 | 6 | 2019 |
Application of modeling and simulation to identify a shortened study duration and novel bioequivalence metric for a long-acting intrauterine system S Sharan, S Choi, Y Zou, Y Wang, MJ Kim, L Fang, S Choi, F Makhlouf, ... The AAPS Journal 24 (3), 63, 2022 | 4 | 2022 |
Impact of model misspecification on model-based tests in PK studies with parallel design: real case and simulation studies M Guhl, F Mercier, C Hofmann, S Sharan, M Donnelly, K Feng, W Sun, ... Journal of Pharmacokinetics and Pharmacodynamics 49 (5), 557-577, 2022 | 3 | 2022 |
Review of Complex Generic Drugs Delivered Through the Female Reproductive Tract: The Current Competitive Landscape and Emerging Role of Physiologically Based Pharmacokinetic … M Donnelly, E Tsakalozou, S Sharan, T Straubinger, R Bies, L Zhao Journal of Clinical Pharmacology 60, 2020 | 3 | 2020 |
Regulatory Science to Promote Access to Intrauterine Systems for Women in the United States. S Sharan, Y Wang, M Donnelly, Y Zou, L Fang, MJ Kim, L Zhao Journal of Clinical Pharmacology 60, 2020 | 3 | 2020 |