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David B Sauer
David B Sauer
University of Oxford - Centre for Medicines Discovery
Verified email at cmd.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger
J Liao, H Li, W Zeng, DB Sauer, R Belmares, Y Jiang
Science 335 (6069), 686-690, 2012
3012012
Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites
MG Derebe, DB Sauer, W Zeng, A Alam, N Shi, Y Jiang
Proceedings of the National Academy of Sciences 108 (2), 598-602, 2011
1272011
Sodium and potassium competition in potassium-selective and non-selective channels
DB Sauer, W Zeng, J Canty, Y Lam, Y Jiang
Nature communications 4 (1), 2721, 2013
702013
Predicting the optimal growth temperatures of prokaryotes using only genome derived features
DB Sauer, DN Wang
Bioinformatics 35 (18), 3224-3231, 2019
602019
Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation
DB Sauer, W Zeng, S Raghunathan, Y Jiang
Proceedings of the National Academy of Sciences 108 (40), 16634-16639, 2011
552011
Structure and inhibition mechanism of the human citrate transporter NaCT
DB Sauer, J Song, B Wang, JK Hilton, NK Karpowich, JA Mindell, WJ Rice, ...
Nature 591 (7848), 157-161, 2021
492021
Structural basis for the reaction cycle of DASS dicarboxylate transporters
DB Sauer, N Trebesch, JJ Marden, N Cocco, J Song, A Koide, S Koide, ...
Elife 9, e61350, 2020
492020
Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel
C Kong, W Zeng, S Ye, L Chen, DB Sauer, Y Lam, MG Derebe, Y Jiang
Elife 1, e00184, 2012
352012
Rapid bioinformatic identification of thermostabilizing mutations
DB Sauer, NK Karpowich, JM Song, DN Wang
Biophysical Journal 109 (7), 1420-1428, 2015
312015
Influence of lipid chemistry on the osmotic response of cell membranes: effect of non-bilayer forming lipids
MC Hull, DB Sauer, JS Hovis
The Journal of Physical Chemistry B 108 (40), 15890-15895, 2004
262004
Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus
DN Brawley, DB Sauer, J Li, X Zheng, A Koide, GS Jedhe, T Suwatthee, ...
Nature chemical biology 18 (7), 706-712, 2022
252022
The conserved potassium channel filter can have distinct ion binding profiles: Structural analysis of rubidium, cesium, and barium binding in NaK2K
YL Lam, W Zeng, DB Sauer, Y Jiang
Journal of General Physiology 144 (2), 181-192, 2014
222014
The ups and downs of elevator‐type di‐/tricarboxylate membrane transporters
DB Sauer, B Wang, JC Sudar, J Song, J Marden, WJ Rice, DN Wang
The FEBS journal 289 (6), 1515-1523, 2022
102022
Structural basis of ion – substrate coupling in the Na+-dependent dicarboxylate transporter VcINDY
DB Sauer, JJ Marden, JC Sudar, J Song, C Mulligan, DN Wang
Nature communications 13 (1), 2644, 2022
82022
The solute carrier SPNS2 recruits PI (4, 5) P2 to synergistically regulate transport of sphingosine-1-phosphate
H Tang, H Li, D Prakaash, C Pedebos, X Qiu, DB Sauer, S Khalid, K Duerr, ...
Molecular Cell 83 (15), 2739-2752. e5, 2023
62023
Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
CD Kinz-Thompson, M Lopez Redondo, C Mulligan, DB Sauer, ...
Biorxiv, 2022.05. 01.490196, 2022
42022
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
H Li, A Pike, YN Chang, D Prakaash, Z Gelova, J Stanka, C Moreau, ...
1*2023
High-throughput expression and purification of human solute carriers for structural and biochemical studies
S Raturi, H Li, YN Chang, A Scacioc, T Bohstedt, A Fernandez-Cid, ...
Journal of Visualized Experiments, 2023
12023
Using machine learning to predict quantitative phenotypes from protein and nucleic acid sequences
DB Sauer, DN Wang
bioRxiv, 677328, 2019
12019
The binding and mechanism of a positive allosteric modulator of Kv3 channels
Q Liang, G Chi, L Cirqueira, L Zhi, A Marasco, N Pilati, MJ Gunthorpe, ...
Nature Communications 15 (1), 2533, 2024
2024
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