| A receptor-mediated pathway for cholesterol homeostasis MS Brown, JL Goldstein Science 232 (4746), 34-47, 1986 | 7739 | 1986 |
| Regulation of the mevalonate pathway JL Goldstein, MS Brown Nature 343 (6257), 425-430, 1990 | 6731 | 1990 |
| SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver JD Horton, JL Goldstein, MS Brown The Journal of clinical investigation 109 (9), 1125-1131, 2002 | 5913 | 2002 |
| The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor MS Brown, JL Goldstein Cell 89 (3), 331-340, 1997 | 4745 | 1997 |
| Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition JL Goldstein, YK Ho, SK Basu, MS Brown Proceedings of the National Academy of Sciences 76 (1), 333-337, 1979 | 3451 | 1979 |
| Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis MS Brown, JL Goldstein Annual review of biochemistry 52 (1), 223-261, 1983 | 3170 | 1983 |
| Coated pits, coated vesicles, and receptor-mediated endocytosis JL Goldstein, RGW Anderson, MS Brown Nature 279 (5715), 679-685, 1979 | 2620 | 1979 |
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs J Ye, RB Rawson, R Komuro, X Chen, UP Davé, R Prywes, MS Brown, ... Molecular cell 6 (6), 1355-1364, 2000 | 2155 | 2000 |
| Receptor-mediated endocytosis: concepts emerging from the LDL receptor system JL Goldstein, MS Brown, RGW Anderson, DW Russell, WJ Schneider Annual review of cell biology 1 (1), 1-39, 1985 | 2113 | 1985 |
| Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ JJ Repa, G Liang, J Ou, Y Bashmakov, JMA Lobaccaro, I Shimomura, ... Genes & development 14 (22), 2819-2830, 2000 | 2028 | 2000 |
| Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. S Ishibashi, MS Brown, JL Goldstein, RD Gerard, RE Hammer, J Herz The Journal of clinical investigation 92 (2), 883-893, 1993 | 2016 | 1993 |
| Protein sensors for membrane sterols JL Goldstein, RA DeBose-Boyd, MS Brown Cell 124 (1), 35-46, 2006 | 1876 | 2006 |
| [19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells JL Goldstein, SK Basu, MS Brown Methods in enzymology 98, 241-260, 1983 | 1858 | 1983 |
| Binding and degradation of low density lipoproteins by cultured human fibroblasts: comparison of cells from a normal subject and from a patient with homozygous familial … JL Goldstein, MS Brown Journal of Biological Chemistry 249 (16), 5153-5162, 1974 | 1823 | 1974 |
| The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA T Yamamoto, CG Davis, MS Brown, WJ Schneider, ML Casey, ... Cell 39 (1), 27-38, 1984 | 1748 | 1984 |
| Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans MS Brown, J Ye, RB Rawson, JL Goldstein Cell 100 (4), 391-398, 2000 | 1700 | 2000 |
| A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood MS Brown, JL Goldstein Proceedings of the National Academy of Sciences 96 (20), 11041-11048, 1999 | 1692 | 1999 |
| The LDL receptor JL Goldstein, MS Brown Arteriosclerosis, thrombosis, and vascular biology 29 (4), 431-438, 2009 | 1686 | 2009 |
| Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes JD Horton, NA Shah, JA Warrington, NN Anderson, SW Park, MS Brown, ... Proceedings of the National Academy of Sciences 100 (21), 12027-12032, 2003 | 1618 | 2003 |
| Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. MS Brown, JL Goldstein Journal of lipid research 21 (5), 505-517, 1980 | 1522 | 1980 |
