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R. James Christie
R. James Christie
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Polymeric micelles for nano-scale drug delivery
K Miyata, RJ Christie, K Kataoka
Reactive and Functional Polymers 71 (3), 227-234, 2011
5162011
Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery
Y Matsumoto, JW Nichols, K Toh, T Nomoto, H Cabral, Y Miura, ...
Nature nanotechnology 11 (6), 533-538, 2016
4062016
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery
S Matsumoto, RJ Christie, N Nishiyama, K Miyata, A Ishii, M Oba, ...
Biomacromolecules 10 (1), 119-127, 2009
3742009
Polymeric micelles from poly (ethylene glycol)–poly (amino acid) block copolymer for drug and gene delivery
K Osada, RJ Christie, K Kataoka
Journal of The Royal Society Interface 6 (suppl_3), S325-S339, 2009
2602009
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection
RJ Christie, Y Matsumoto, K Miyata, T Nomoto, S Fukushima, K Osada, ...
Acs Nano 6 (6), 5174-5189, 2012
2202012
Design strategies to improve soluble macromolecular delivery constructs
RJ Christie, DW Grainger
Advanced drug delivery reviews 55 (3), 421-437, 2003
1492003
Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors
Y Oe, RJ Christie, M Naito, SA Low, S Fukushima, K Toh, Y Miura, ...
Biomaterials 35 (27), 7887-7895, 2014
1392014
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles
HJ Kim, H Takemoto, Y Yi, M Zheng, Y Maeda, H Chaya, K Hayashi, P Mi, ...
ACS nano 8 (9), 8979-8991, 2014
1372014
Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles
F Pittella, K Miyata, Y Maeda, T Suma, S Watanabe, Q Chen, RJ Christie, ...
Journal of controlled release 161 (3), 868-874, 2012
1302012
Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides
RJ Christie, R Fleming, B Bezabeh, R Woods, S Mao, J Harper, A Joseph, ...
Journal of controlled release 220, 660-670, 2015
1282015
Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery
M Oba, K Miyata, K Osada, RJ Christie, M Sanjoh, W Li, S Fukushima, ...
Biomaterials 32 (2), 652-663, 2011
1182011
Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG
T Suma, K Miyata, Y Anraku, S Watanabe, RJ Christie, H Takemoto, ...
ACS nano 6 (8), 6693-6705, 2012
1102012
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines
RJ Christie, K Miyata, Y Matsumoto, T Nomoto, D Menasco, TC Lai, ...
Biomacromolecules 12 (9), 3174-3185, 2011
1092011
Minireview: delivering the code: polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies
RJ Christie, N Nishiyama, K Kataoka
Endocrinology 151 (2), 466-473, 2010
982010
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core
HJ Kim, K Miyata, T Nomoto, M Zheng, A Kim, X Liu, H Cabral, RJ Christie, ...
Biomaterials 35 (15), 4548-4556, 2014
892014
Efficient preparation of site-specific antibody–drug conjugates using cysteine insertion
N Dimasi, R Fleming, H Zhong, B Bezabeh, K Kinneer, RJ Christie, ...
Molecular pharmaceutics 14 (5), 1501-1516, 2017
782017
Solution structure of the 3'-5'cyclic dinucleotide d (pApA). A combined NMR, UV melting, and molecular mechanics study.
MJ Blommers, CA Haasnoot, JA Walters, GA Van der Marel, ...
Biochemistry 27 (22), 8361-8369, 1988
77*1988
Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography
Y Matsumoto, T Nomoto, H Cabral, Y Matsumoto, S Watanabe, ...
Biomedical optics express 1 (4), 1209-1216, 2010
672010
Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles
K Osada, T Shiotani, TA Tockary, D Kobayashi, H Oshima, S Ikeda, ...
Biomaterials 33 (1), 325-332, 2012
662012
Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA
M Sanjoh, K Miyata, RJ Christie, T Ishii, Y Maeda, F Pittella, S Hiki, ...
Biomacromolecules 13 (11), 3641-3649, 2012
652012
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