Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 RJ Molenaar, D Botman, MA Smits, VV Hira, SA van Lith, J Stap, ... Cancer research 75 (22), 4790-4802, 2015 | 159 | 2015 |
PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports MJM Uijen, YHW Derks, RIJ Merkx, MGM Schilham, J Roosen, BM Privé, ... European journal of nuclear medicine and molecular imaging 48 (13), 4350-4368, 2021 | 88 | 2021 |
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG AC Navis, SP Niclou, F Fack, D Stieber, S van Lith, K Verrijp, A Wright, ... Acta neuropathologica communications 1, 1-12, 2013 | 76 | 2013 |
Exendin‐4 analogs in insulinoma theranostics TJP Jansen, SAM van Lith, M Boss, M Brom, L Joosten, M Béhé, ... Journal of Labelled Compounds and Radiopharmaceuticals 62 (10), 656-672, 2019 | 68 | 2019 |
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers? SAM van Lith, AC Navis, K Verrijp, SP Niclou, R Bjerkvig, P Wesseling, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (1), 66-74, 2014 | 60 | 2014 |
Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein AC Navis, SAM van Lith, SMJ van Duijnhoven, M de Pooter, B Yetkin-Arik, ... Acta neuropathologica 130, 131-144, 2015 | 50 | 2015 |
Self-assembling VHH-elastin-like peptides for photodynamic nanomedicine J Pille, SAM van Lith, JCM van Hest, WPJ Leenders Biomacromolecules 18 (4), 1302-1310, 2017 | 49 | 2017 |
Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre) clinical studies BM Privé, MA Boussihmad, B Timmermans, WA van Gemert, SMB Peters, ... European journal of nuclear medicine and molecular imaging 50 (7), 1906-1918, 2023 | 42 | 2023 |
Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress K Lenting, M Khurshed, TH Peeters, CNAM van den Heuvel, SAM van Lith, ... The FASEB Journal 33 (1), 557-571, 2019 | 41 | 2019 |
Legomedicine A Versatile Chemo-Enzymatic Approach for the Preparation of Targeted Dual-Labeled Llama Antibody–Nanoparticle Conjugates SAM van Lith, SMJ van Duijnhoven, AC Navis, WPJ Leenders, E Dolk, ... Bioconjugate Chemistry 28 (2), 539-548, 2017 | 40 | 2017 |
The effect of subcellular localization on the efficiency of EGFR-targeted VHH photosensitizer conjugates SAM van Lith, D van den Brand, R Wallbrecher, L Wübbeke, ... European Journal of Pharmaceutics and Biopharmaceutics 124, 63-72, 2018 | 39 | 2018 |
Tumor cells in search for glutamate: an alternative explanation for increased invasiveness of IDH1 mutant gliomas SAM van Lith, R Molenaar, CJF van Noorden, WPJ Leenders Neuro-oncology 16 (12), 1669-1670, 2014 | 37 | 2014 |
Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes SCHA van der Steen, R Raavé, S Langerak, L van Houdt, ... European Journal of Pharmaceutics and Biopharmaceutics 113, 229-239, 2017 | 30 | 2017 |
A conjugate of an anti‐epidermal growth factor receptor (egfr) vhh and a cell‐penetrating peptide drives receptor internalization and blocks egfr activation SAM van Lith, D van den Brand, R Wallbrecher, SMJ van Duijnhoven, ... ChemBioChem 18 (24), 2390-2394, 2017 | 25 | 2017 |
Site-specific dual-labeling of a VHH with a chelator and a photosensitizer for nuclear imaging and targeted photodynamic therapy of EGFR-positive tumors E Renard, E Collado Camps, C Canovas, A Kip, M Gotthardt, M Rijpkema, ... Cancers 13 (3), 428, 2021 | 22 | 2021 |
EpCAM-binding DARPins for targeted photodynamic therapy of ovarian cancer D van den Brand, SAM van Lith, JM de Jong, MAJ Gorris, ... Cancers 12 (7), 1762, 2020 | 20 | 2020 |
Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate TH Peeters, K Lenting, V Breukels, SAM van Lith, CNAM van den Heuvel, ... Cancer & Metabolism 7, 1-13, 2019 | 19 | 2019 |
Profiling of the metabolic transcriptome via single molecule molecular inversion probes T de Bitter, C van de Water, C van den Heuvel, C Zeelen, A Eijkelenboom, ... Scientific reports 7 (1), 11402, 2017 | 19 | 2017 |
Receptor-targeted photodynamic therapy of glucagon-like peptide 1 receptor–positive lesions M Boss, D Bos, C Frielink, G Sandker, P Bronkhorst, SAM van Lith, ... Journal of Nuclear Medicine 61 (11), 1588-1593, 2020 | 17 | 2020 |
Theranostic PSMA ligands with optimized backbones for intraoperative multimodal imaging and photodynamic therapy of prostate cancer YHW Derks, SAM van Lith, HIV Amatdjais-Groenen, LWM Wouters, A Kip, ... European Journal of Nuclear Medicine and Molecular Imaging 49 (7), 2425-2435, 2022 | 16 | 2022 |