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Alessandro Bitto
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Year
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome
A Bitto, AS Grillo, TK Ito, IB Stanaway, BMG Nguyen, K Ying, H Tung, ...
Nature Metabolism 5 (6), 955-967, 2023
62023
17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex (vol 20, e13328, 2021)
DE Harrison, R Strong, P Reifsnyder, N Kumar, E Fernandez, K Flurkey, ...
AGING CELL 21 (11), 2022
2022
Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide …
JA Whitson, R Johnson, L Wang, TK Bammler, SI Imai, H Zhang, ...
GeroScience 44 (3), 1621-1639, 2022
72022
LEVERAGING THE NDUFS4-/-MOUSE AS A PLATFORM FOR TESTING LONGEVITY INTERVENTIONS
P Ramalingam, M Gutkin, M Poulos, J Butler
Innovation in Aging 6 (S1), 731, 2022
2022
Antiaging diets: Separating fact from fiction
MB Lee, CM Hill, A Bitto, M Kaeberlein
Science 374 (6570), eabe7365, 2021
872021
University of Washington Nathan Shock Center: innovation to advance aging research
M Kaeberlein, A Bitto, MJ Dunham, W Ladiges, SI Lee, MJ MacCoss, ...
GeroScience 43 (5), 2161-2165, 2021
12021
Evidence that C/EBP-β LAP increases fat metabolism and protects against diet-induced obesity in response to mTOR inhibition
A Bitto, N Tatom, T Krivak, P Grotz, M Kaeberlein
Frontiers in Aging 2, 738512, 2021
102021
The AGE Presents Introduction to Geroscience video lecture series
A Bitto, MB Lee, CM Hill, R Korstanje, M Kaeberlein
GeroScience 43 (4), 1697-1701, 2021
12021
Proceedings from the annual University of Washington geroscience symposium, October 23, 2020
MB Lee, A Bitto, M Kaeberlein
GeroScience, 1-5, 2021
12021
The NDUFS4 knockout mouse: a dual threat model of childhood mitochondrial disease and normative aging
AS Grillo, A Bitto, M Kaeberlein
Mitochondrial Medicine: Volume 3: Manipulating Mitochondria and Disease …, 2021
102021
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
DE Harrison, R Strong, P Reifsnyder, N Kumar, E Fernandez, K Flurkey, ...
Aging Cell 20 (5), e13328, 2021
592021
Geroscience approaches to obesity
A Bitto, M Kaeberlein
Innovation in Aging 5 (Suppl 1), 824, 2021
2021
SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts
JA Whitson, A Bitto, H Zhang, MT Sweetwyne, R Coig, S Bhayana, ...
Aging Cell 19 (10), e13213, 2020
462020
The importance of diversity and outreach in geroscience research: Insights from the Annual Biomedical Research Conference for Minority Students
MB Lee, D Datta, CM Hill, A Bitto
GeroScience 42, 1005-1012, 2020
42020
Regional metabolic signatures in the Ndufs4 (KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease
SC Johnson, EB Kayser, R Bornstein, J Stokes, A Bitto, KY Park, A Pan, ...
Molecular genetics and metabolism 130 (2), 118-132, 2020
392020
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome
A Bitto, A Grillo, M Kaeberlein
Innovation in Aging 4 (Suppl 1), 886, 2020
2020
Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease
A Grillo, A Bitto, M Kaeberlein
Innovation in Aging 4 (Suppl 1), 889, 2020
2020
Is aging an acquired mitochondrial disease?
A Bitto
Innovation in Aging 3 (Suppl 1), S394, 2019
12019
AGING AND MITOCHONDRIAL DISEASE: SHARED MECHANISMS AND THERAPIES?
A Bitto, H Tung, K Ying, DL Smith, EB Kayser, PG Morgan, MM Sedensky, ...
Innovation in Aging 3 (Supplement_1), S395-S395, 2019
2019
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases
SC Johnson, F Martinez, A Bitto, B Gonzalez, C Tazaerslan, C Cohen, ...
Kidney international 95 (2), 455-466, 2019
412019
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Articles 1–20