LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration M Deng, X Gui, J Kim, L Xie, W Chen, Z Li, L He, Y Chen, H Chen, W Luo, ... Nature 562 (7728), 605-609, 2018 | 200 | 2018 |
Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis H Gu, C Chen, X Hao, C Wang, X Zhang, Z Li, H Shao, H Zeng, Z Yu, ... The Journal of clinical investigation 126 (12), 4537-4553, 2016 | 80 | 2016 |
Hypoxic metabolism in human hematopoietic stem cells F Kocabas, L Xie, J Xie, Z Yu, RJ DeBerardinis, W Kimura, SW Thet, ... Cell & bioscience 5, 1-16, 2015 | 73 | 2015 |
ANGPTL2/LILRB2 signaling promotes the propagation of lung cancer cells X Liu, X Yu, J Xie, M Zhan, Z Yu, L Xie, H Zeng, F Zhang, G Chen, X Yi, ... Oncotarget 6 (25), 21004, 2015 | 68 | 2015 |
PPM1K regulates hematopoiesis and leukemogenesis through CDC20-mediated ubiquitination of MEIS1 and p21 X Liu, F Zhang, Y Zhang, X Li, C Chen, M Zhou, Z Yu, Y Liu, Y Zhao, ... Cell reports 23 (5), 1461-1475, 2018 | 63 | 2018 |
Paired immunoglobulin-like receptor B regulates platelet activation X Fan, P Shi, J Dai, Y Lu, X Chen, X Liu, K Zhang, X Wu, Y Sun, K Wang, ... Blood, The Journal of the American Society of Hematology 124 (15), 2421-2430, 2014 | 57 | 2014 |
LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells Z Li, M Deng, F Huang, C Jin, S Sun, H Chen, X Liu, L He, AH Sadek, ... Cellular & molecular immunology 17 (3), 272-282, 2020 | 43 | 2020 |
Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow J Zheng, Z Lu, F Kocabas, RT Böttcher, M Costell, X Kang, X Liu, ... Blood, The Journal of the American Society of Hematology 123 (7), 992-1001, 2014 | 42 | 2014 |
JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/β-catenin/CCND1 signaling Y Zhang, F Xia, X Liu, Z Yu, L Xie, L Liu, C Chen, H Jiang, X Hao, X He, ... The Journal of Clinical Investigation 128 (5), 1737-1751, 2018 | 40 | 2018 |
CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27kip1 signaling F Zhang, X Liu, C Chen, J Zhu, Z Yu, J Xie, L Xie, H Bai, Y Zhang, X Fang, ... Haematologica 102 (4), 707, 2017 | 32 | 2017 |
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells H Chen, Y Chen, M Deng, S John, X Gui, A Kansagra, W Chen, J Kim, ... Journal for ImmunoTherapy of Cancer 8 (2), 2020 | 30 | 2020 |
Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer M Deng, H Chen, X Liu, R Huang, Y He, B Yoo, J Xie, S John, N Zhang, ... Antibody Therapeutics 4 (1), 16-33, 2021 | 27 | 2021 |
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis G Wu, Y Xu, RD Schultz, H Chen, J Xie, M Deng, X Liu, X Gui, S John, ... Nature cancer 2 (11), 1170-1184, 2021 | 26 | 2021 |
DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma RJ Fu, W He, XB Wang, L Li, HB Zhao, XY Liu, Z Pang, GQ Chen, ... Cell Death & Disease 8 (7), e2952-e2952, 2017 | 20 | 2017 |
ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways H Zeng, H Gu, C Chen, M Li, F Xia, L Xie, X Liu, F Zhang, X Tong, J Wang, ... Oncotarget 7 (25), 38347, 2016 | 14 | 2016 |
LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions P Zhao, Y Xu, LL Jiang, X Fan, Z Ku, L Li, X Liu, M Deng, H Arase, JJ Zhu, ... Molecular neurodegeneration 17 (1), 44, 2022 | 13 | 2022 |
B7-H4 enhances the differentiation of murine leukemia-initiating cells via the PTEN/AKT/RCOR2/RUNX1 pathways F Xia, Y Zhang, L Xie, H Jiang, H Zeng, C Chen, L Liu, X He, X Hao, ... Leukemia 31 (10), 2260-2264, 2017 | 11 | 2017 |
Blocking LAIR1 signaling in immune cells inhibits tumor development J Xie, X Gui, M Deng, H Chen, Y Chen, X Liu, Z Ku, L Tan, R Huang, Y He, ... Frontiers in immunology 13, 996026, 2022 | 10 | 2022 |
Hypoxic metabolism in human hematopoietic stem cells. Cell Biosci 5: 39 F Kocabas, L Xie, J Xie, Z Yu, RJ DeBerardinis, W Kimura, S Thet, ... | 5 | 2015 |
IO-108, A fully human therapeutic antibody blocking the myeloid checkpoint LILRB2/ILT4, promotes innate and adaptive anti-cancer immunity in preclinical studies JT Ma, X Liu, R Stafford, K McCutcheon, H Chen, T Huang, H Tian, ... Cancer Res 82 (12_suppl), 601-601, 2022 | 3 | 2022 |