| Purification and cloning of amyloid precursor protein β-secretase from human brain S Sinha, JP Anderson, R Barbour, GS Basi, R Caccavello, D Davis, ... Nature 402 (6761), 537-540, 1999 | 2252 | 1999 |
| BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer’s disease therapeutics SL Roberds, J Anderson, G Basi, MJ Bienkowski, DG Branstetter, ... Human molecular genetics 10 (12), 1317-1324, 2001 | 982 | 2001 |
| Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth GS Basi, RD Jacobson, I Virág, J Schilling, JHP Skene Cell 49 (6), 785-791, 1987 | 442 | 1987 |
| Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions CM Eischen, TJ Kottke, LM Martins, GS Basi, JS Tung, WC Earnshaw, ... Blood, The Journal of the American Society of Hematology 90 (3), 935-943, 1997 | 325 | 1997 |
| Restricted location of PSEN2/γ-secretase determines substrate specificity and generates an intracellular Aβ pool R Sannerud, C Esselens, P Ejsmont, R Mattera, L Rochin, ... Cell 166 (1), 193-208, 2016 | 309 | 2016 |
| Polo-like kinase 2 (PLK2) phosphorylates α-synuclein at serine 129 in central nervous system KJ Inglis, D Chereau, EF Brigham, SS Chiou, S Schöbel, NL Frigon, ... Journal of Biological Chemistry 284 (5), 2598-2602, 2009 | 263 | 2009 |
| Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis LM Martins, T Kottke, PW Mesner, GS Basi, S Sinha, N Frigon, E Tatar, ... Journal of Biological Chemistry 272 (11), 7421-7430, 1997 | 240 | 1997 |
| Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis LM Martins, PW Mesner, TJ Kottke, GS Basi, S Sinha, JS Tung, ... Blood, The Journal of the American Society of Hematology 90 (11), 4283-4296, 1997 | 173 | 1997 |
| Treatment strategies targeting amyloid β-protein D Schenk, GS Basi, MN Pangalos Cold Spring Harbor perspectives in medicine 2 (9), a006387, 2012 | 159 | 2012 |
| Immunotherapy reduces vascular amyloid-β in PDAPP mice S Schroeter, K Khan, R Barbour, MT Doan, M Chen, T Guido, D Gill, ... Journal of Neuroscience 28 (27), 6787-6793, 2008 | 152 | 2008 |
| Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis K Samejima, PA Svingen, GS Basi, T Kottke, PW Mesner, L Stewart, ... Journal of Biological Chemistry 274 (7), 4335-4340, 1999 | 139 | 1999 |
| Antagonistic effects of β-site amyloid precursor protein-cleaving enzymes 1 and 2 on β-amyloid peptide production in cells G Basi, N Frigon, R Barbour, T Doan, G Gordon, L McConlogue, S Sinha, ... Journal of Biological Chemistry 278 (34), 31512-31520, 2003 | 135 | 2003 |
| Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies DW Shineman, GS Basi, JL Bizon, CA Colton, BD Greenberg, BA Hollister, ... Alzheimer's research & therapy 3, 1-13, 2011 | 132 | 2011 |
| A neural-specific GAP-43 core promoter located between unusual DNA elements that interact to regulate its activity E Nedivi, GS Basi, IV Akey, JH Skene Journal of Neuroscience 12 (3), 691-704, 1992 | 125 | 1992 |
| Alternative splicing of a Drosophila tropomyosin gene generates muscle tropomyosin isoforms with different carboxy-terminal ends GS Basi, M Boardman, RV Storti Molecular and cellular biology, 1984 | 121 | 1984 |
| Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: Support for a sequential model of γ-secretase intramembrane proteolysis … TL Kukar, TB Ladd, P Robertson, SA Pintchovski, B Moore, MA Bann, ... Journal of Biological Chemistry 286 (46), 39804-39812, 2011 | 82 | 2011 |
| Structure and DNA sequence of the tropomyosin I gene from Drosophila melanogaster. GS Basi, RV Storti Journal of Biological Chemistry 261 (2), 817-827, 1986 | 78 | 1986 |
| Antibody capture of soluble Aβ does not reduce cortical Aβ amyloidosis in the PDAPP mouse P Seubert, R Barbour, K Khan, R Motter, P Tang, D Kholodenko, K Kling, ... Neurodegenerative Diseases 5 (2), 65-71, 2008 | 77 | 2008 |
| Identification of γ-secretase inhibitor potency determinants on presenilin B Zhao, M Yu, M Neitzel, J Marugg, J Jagodzinski, M Lee, K Hu, D Schenk, ... Journal of biological chemistry 283 (5), 2927-2938, 2008 | 74 | 2008 |
| Amyloid β-protein precursor juxtamembrane domain regulates specificity of γ-secretase-dependent cleavages Z Ren, D Schenk, GS Basi, IP Shapiro Journal of biological chemistry 282 (48), 35350-35360, 2007 | 74 | 2007 |
