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Demetrios Braddock
Demetrios Braddock
Verified email at yale.edu
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Cited by
Year
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
AK Madiraju, DM Erion, Y Rahimi, XM Zhang, DT Braddock, RA Albright, ...
Nature 510 (7506), 542-546, 2014
13362014
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment
CJ Cheng, R Bahal, IA Babar, Z Pincus, F Barrera, C Liu, A Svoronos, ...
Nature 518 (7537), 107-110, 2015
8392015
Structure and dynamics of KH domains from FBP bound to single-stranded DNA
DT Braddock, JM Louis, JL Baber, D Levens, GM Clore
Nature 415 (6875), 1051-1056, 2002
2072002
Molecular basis of sequence‐specific single‐stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single‐stranded DNA
DT Braddock, JL Baber, D Levens, GM Clore
The EMBO Journal, 2002
1802002
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery
R Bahal, N Ali McNeer, E Quijano, Y Liu, P Sulkowski, A Turchick, YC Lu, ...
Nature communications 7 (1), 13304, 2016
1582016
ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
RA Albright, P Stabach, W Cao, D Kavanagh, I Mullen, AA Braddock, ...
Nature communications 6 (1), 10006, 2015
1322015
Treatment of autoimmune premature ovarian failure: case report
SN Kalantaridou, DT Braddock, NJ Patronas, LM Nelson
Human Reproduction 14 (7), 1777-1782, 1999
931999
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion
LP Saunders, A Ouellette, R Bandle, WC Chang, H Zhou, RN Misra, ...
Molecular cancer therapeutics 7 (10), 3352-3362, 2008
882008
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c‐myc inhibition
GV Crichlow, H Zhou, H Hsiao, KB Frederick, M Debrosse, Y Yang, ...
The EMBO Journal 27 (1), 277-289, 2008
672008
Anti-tumor activity of miniPEG-γ-modified PNAs to inhibit microRNA-210 for cancer therapy
A Gupta, E Quijano, Y Liu, R Bahal, SE Scanlon, E Song, WC Hsieh, ...
Molecular Therapy-Nucleic Acids 9, 111-119, 2017
662017
Rapid identification of medium-to large-scale interdomain motion in modular proteins using dipolar couplings
DT Braddock, M Cai, JL Baber, Y Huang, GM Clore
Journal of the American Chemical Society 123 (35), 8634-8635, 2001
632001
Quantitative Characterization of the Interactions among c-myc Transcriptional Regulators FUSE, FBP, and FIR
H Hsiao, A Nath, CY Lin, EJ Folta-Stogniew, E Rhoades, DT Braddock
Biochemistry 49 (22), 4620-4634, 2010
602010
NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter
JR Huth, L Yu, I Collins, J Mack, R Mendoza, B Isaac, DT Braddock, ...
Journal of medicinal chemistry 47 (20), 4851-4857, 2004
552004
Human heterozygous ENPP1 deficiency is associated with early onset osteoporosis, a phenotype recapitulated in a mouse model of Enpp1 deficiency
R Oheim, K Zimmerman, ND Maulding, J Stürznickel, S von Kroge, ...
Journal of Bone and Mineral Research 35 (3), 528-539, 2020
462020
NPP4 is a procoagulant enzyme on the surface of vascular endothelium
RA Albright, WC Chang, D Robert, DL Ornstein, W Cao, L Liu, ME Redick, ...
Blood, The Journal of the American Society of Hematology 120 (22), 4432-4440, 2012
442012
Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke*♦
RA Albright, DL Ornstein, W Cao, WC Chang, D Robert, M Tehan, ...
Journal of Biological Chemistry 289 (6), 3294-3306, 2014
392014
Desmoplastic melanoma: a 12-year experience with sentinel lymph node biopsy
PN Broer, ME Walker, C Goldberg, S Buonocore, DT Braddock, R Lazova, ...
European Journal of Surgical Oncology (EJSO) 39 (7), 681-685, 2013
392013
Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution
LP Saunders, W Cao, WC Chang, RA Albright, DT Braddock, M Enrique
Journal of Biological Chemistry 286 (34), 30130-30141, 2011
392011
Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia
M Caffrey, DT Braddock, JM Louis, MA Abu-Asab, D Kingma, L Liotta, ...
Journal of Biological Chemistry 275 (26), 19877-19882, 2000
392000
Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: Side-chain lactam bridges to constrain the conformation
P Luo, DT Braddock, RM Subramanian, SC Meredith, DG Lynn
Biochemistry 33 (41), 12367-12377, 1994
381994
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