Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase AK Madiraju, DM Erion, Y Rahimi, XM Zhang, DT Braddock, RA Albright, ... Nature 510 (7506), 542-546, 2014 | 1336 | 2014 |
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment CJ Cheng, R Bahal, IA Babar, Z Pincus, F Barrera, C Liu, A Svoronos, ... Nature 518 (7537), 107-110, 2015 | 839 | 2015 |
Structure and dynamics of KH domains from FBP bound to single-stranded DNA DT Braddock, JM Louis, JL Baber, D Levens, GM Clore Nature 415 (6875), 1051-1056, 2002 | 207 | 2002 |
Molecular basis of sequence‐specific single‐stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single‐stranded DNA DT Braddock, JL Baber, D Levens, GM Clore The EMBO Journal, 2002 | 180 | 2002 |
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery R Bahal, N Ali McNeer, E Quijano, Y Liu, P Sulkowski, A Turchick, YC Lu, ... Nature communications 7 (1), 13304, 2016 | 158 | 2016 |
ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy RA Albright, P Stabach, W Cao, D Kavanagh, I Mullen, AA Braddock, ... Nature communications 6 (1), 10006, 2015 | 132 | 2015 |
Treatment of autoimmune premature ovarian failure: case report SN Kalantaridou, DT Braddock, NJ Patronas, LM Nelson Human Reproduction 14 (7), 1777-1782, 1999 | 93 | 1999 |
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion LP Saunders, A Ouellette, R Bandle, WC Chang, H Zhou, RN Misra, ... Molecular cancer therapeutics 7 (10), 3352-3362, 2008 | 88 | 2008 |
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c‐myc inhibition GV Crichlow, H Zhou, H Hsiao, KB Frederick, M Debrosse, Y Yang, ... The EMBO Journal 27 (1), 277-289, 2008 | 67 | 2008 |
Anti-tumor activity of miniPEG-γ-modified PNAs to inhibit microRNA-210 for cancer therapy A Gupta, E Quijano, Y Liu, R Bahal, SE Scanlon, E Song, WC Hsieh, ... Molecular Therapy-Nucleic Acids 9, 111-119, 2017 | 66 | 2017 |
Rapid identification of medium-to large-scale interdomain motion in modular proteins using dipolar couplings DT Braddock, M Cai, JL Baber, Y Huang, GM Clore Journal of the American Chemical Society 123 (35), 8634-8635, 2001 | 63 | 2001 |
Quantitative Characterization of the Interactions among c-myc Transcriptional Regulators FUSE, FBP, and FIR H Hsiao, A Nath, CY Lin, EJ Folta-Stogniew, E Rhoades, DT Braddock Biochemistry 49 (22), 4620-4634, 2010 | 60 | 2010 |
NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter JR Huth, L Yu, I Collins, J Mack, R Mendoza, B Isaac, DT Braddock, ... Journal of medicinal chemistry 47 (20), 4851-4857, 2004 | 55 | 2004 |
Human heterozygous ENPP1 deficiency is associated with early onset osteoporosis, a phenotype recapitulated in a mouse model of Enpp1 deficiency R Oheim, K Zimmerman, ND Maulding, J Stürznickel, S von Kroge, ... Journal of Bone and Mineral Research 35 (3), 528-539, 2020 | 46 | 2020 |
NPP4 is a procoagulant enzyme on the surface of vascular endothelium RA Albright, WC Chang, D Robert, DL Ornstein, W Cao, L Liu, ME Redick, ... Blood, The Journal of the American Society of Hematology 120 (22), 4432-4440, 2012 | 44 | 2012 |
Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke*♦ RA Albright, DL Ornstein, W Cao, WC Chang, D Robert, M Tehan, ... Journal of Biological Chemistry 289 (6), 3294-3306, 2014 | 39 | 2014 |
Desmoplastic melanoma: a 12-year experience with sentinel lymph node biopsy PN Broer, ME Walker, C Goldberg, S Buonocore, DT Braddock, R Lazova, ... European Journal of Surgical Oncology (EJSO) 39 (7), 681-685, 2013 | 39 | 2013 |
Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution LP Saunders, W Cao, WC Chang, RA Albright, DT Braddock, M Enrique Journal of Biological Chemistry 286 (34), 30130-30141, 2011 | 39 | 2011 |
Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia M Caffrey, DT Braddock, JM Louis, MA Abu-Asab, D Kingma, L Liotta, ... Journal of Biological Chemistry 275 (26), 19877-19882, 2000 | 39 | 2000 |
Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: Side-chain lactam bridges to constrain the conformation P Luo, DT Braddock, RM Subramanian, SC Meredith, DG Lynn Biochemistry 33 (41), 12367-12377, 1994 | 38 | 1994 |