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Refaat Hamed
Refaat Hamed
Associate Professor, Assiut University, University of Bradford
Verified email at aun.edu.eg - Homepage
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Cited by
Year
The enzymes of β-lactam biosynthesis
RB Hamed, JR Gomez-Castellanos, L Henry, C Ducho, MA McDonough, ...
Natural product reports 30 (1), 21-107, 2013
2342013
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans
W Ge, A Wolf, T Feng, C Ho, R Sekirnik, A Zayer, N Granatino, ...
Nature chemical biology 8 (12), 960-962, 2012
1822012
Mechanisms and structures of crotonase superfamily enzymes–how nature controls enolate and oxyanion reactivity
RB Hamed, ET Batchelar, IJ Clifton, CJ Schofield
Cellular and Molecular Life Sciences 65, 2507-2527, 2008
1342008
Evidence for the slow reaction of hypoxia‐inducible factor prolyl hydroxylase 2 with oxygen
E Flashman, LM Hoffart, RB Hamed, JM Bollinger Jr, C Krebs, ...
The FEBS journal 277 (19), 4089-4099, 2010
1062010
Factor‐inhibiting hypoxia‐inducible factor (FIH) catalyses the post‐translational hydroxylation of histidinyl residues within ankyrin repeat domains
M Yang, R Chowdhury, W Ge, RB Hamed, MA McDonough, ...
FEBS Journal 278 (7), 1086-1097, 2011
852011
Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo
SV Sharma, X Tong, C Pubill-Ulldemolins, C Cartmell, EJA Bogosyan, ...
Nature communications 8 (1), 229, 2017
672017
Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde.
R Hopkinson, R Hamed, N Rose, T Claridge, C Schofield
Chembiochem: a European journal of chemical biology 11 (4), 2010
622010
Iron‐Mediated Cleavage of C C Bonds in Vicinal Tricarbonyl Compounds in Water
J Mecinović, RB Hamed, CJ Schofield
Angewandte Chemie International Edition 48 (15), 2796-2800, 2009
622009
The 2-oxoglutarate-dependent oxygenase JMJD6 catalyses oxidation of lysine residues to give 5S-hydroxylysine residues.
M Mantri, ND Loik, RB Hamed, TD Claridge, JS McCullagh, CJ Schofield
Chembiochem: a European journal of chemical biology 12 (4), 531-534, 2011
612011
Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions
D Rotili, M Altun, RB Hamed, C Loenarz, A Thalhammer, RJ Hopkinson, ...
Chemical communications 47 (5), 1488-1490, 2011
412011
Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S, 5S)-trans-carboxymethylproline
RB Hamed, ET Batchelar, J Mecinovic, TDW Claridge, CJ Schofield
ChemBioChem 10 (2), 246, 2009
332009
Crotonase catalysis enables flexible production of functionalized prolines and carbapenams
RB Hamed, L Henry, JR Gomez-Castellanos, J Mecinovic, C Ducho, ...
Journal of the American Chemical Society 134 (1), 471-479, 2012
302012
Thioester Hydrolysis and C C Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily
ET Batchelar, RB Hamed, C Ducho, TDW Claridge, MJ Edelmann, ...
Angewandte Chemie International Edition 47 (48), 9322-9325, 2008
292008
Stereoselective C–C bond formation catalysed by engineered carboxymethylproline synthases
RB Hamed, JR Gomez-Castellanos, A Thalhammer, D Harding, C Ducho, ...
Nature chemistry 3 (5), 365-371, 2011
282011
Synthesis of regio-and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis
C Ducho, RB Hamed, ET Batchelar, JL Sorensen, B Odell, CJ Schofield
Organic & Biomolecular Chemistry 7 (13), 2770-2779, 2009
272009
A natural solution to photoprotection and isolation of the potent polyene antibiotic, marinomycin A
CS Bailey, JS Zarins-Tutt, M Agbo, H Gao, A Diego-Taboada, M Gan, ...
Chemical Science 10 (32), 7549-7553, 2019
232019
Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles
RB Hamed, J Mecinović, C Ducho, TDW Claridge, CJ Schofield
Chemical communications 46 (9), 1413-1415, 2010
232010
Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6
M Mantri, CJ Webby, ND Loik, RB Hamed, ML Nielsen, MA McDonough, ...
MedChemComm 3 (1), 80-85, 2012
202012
Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles
TJ Smart, RB Hamed, TDW Claridge, CJ Schofield
Bioorganic Chemistry 94, 103386, 2020
142020
Crotonases: nature’s exceedingly convertible catalysts
CT Lohans, DY Wang, J Wang, RB Hamed, CJ Schofield
ACS Catalysis 7 (10), 6587-6599, 2017
142017
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