| Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours A Mansurov, J Ishihara, P Hosseinchi, L Potin, TM Marchell, A Ishihara, ... Nature biomedical engineering 4 (5), 531-543, 2020 | 157 | 2020 |
| Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker A Mansurov, P Hosseinchi, K Chang, AL Lauterbach, LT Gray, AT Alpar, ... Nature Biomedical Engineering 6 (7), 819-829, 2022 | 41 | 2022 |
| Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... Nature Biomedical Engineering 4 (1117), 2020 | 31 | 2020 |
| Polymersomes decorated with the SARS-CoV-2 spike protein receptor-binding domain elicit robust humoral and cellular immunity LR Volpatti, RP Wallace, S Cao, MM Raczy, R Wang, LT Gray, AT Alpar, ... ACS central science 7 (8), 1368-1380, 2021 | 28 | 2021 |
| Entropic control of receptor recycling using engineered ligands ACM DeGroot, DJ Busch, CC Hayden, SA Mihelic, AT Alpar, M Behar, ... Biophysical journal 114 (6), 1377-1388, 2018 | 26 | 2018 |
| Engineering targeting materials for therapeutic cancer vaccines PS Briquez, S Hauert, A De Titta, LT Gray, AT Alpar, MA Swartz, ... Frontiers in bioengineering and biotechnology 8, 19, 2020 | 23 | 2020 |
| Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant LT Gray, MM Raczy, PS Briquez, TM Marchell, AT Alpar, RP Wallace, ... Biomaterials 278, 121159, 2021 | 22 | 2021 |
| Immunoengineering approaches for cytokine therapy A Mansurov, A Lauterbach, E Budina, AT Alpar, JA Hubbell, J Ishihara American Journal of Physiology-Cell Physiology 321 (2), C369-C383, 2021 | 21 | 2021 |
| Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ... Arthritis & Rheumatology 73 (5), 769-778, 2021 | 20 | 2021 |
| Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses AC Tremain, RP Wallace, KM Lorentz, TB Thornley, JT Antane, MR Raczy, ... Nature Biomedical Engineering 7 (9), 1142-1155, 2023 | 15 | 2023 |
| Tumor cell-surface binding of immune stimulating polymeric glyco-adjuvant via cysteine-reactive pyridyl disulfide promotes antitumor immunity AJ Slezak, A Mansurov, MM Raczy, K Chang, AT Alpar, AL Lauterbach, ... ACS Central Science 8 (10), 1435-1446, 2022 | 13 | 2022 |
| Seryl-butyrate: a prodrug that enhances butyrate's oral bioavailability and suppresses autoimmune arthritis and experimental autoimmune encephalomyelitis S Cao, E Budina, MM Raczy, A Solanki, M Nguyen, K Hultgren, P Ang, ... | 2 | 2023 |
| Jeffrey A Hubbell Blocking antibodies against integrin-α3, integrin-αM, and integrin-αMβ2 de-differentiate myofibroblasts and reverse lung and kidney fibroses in a mouse model … MJV White, M Ozkan, MM Rączy, JE Gomez-Medellin, KM Koss, AT Alpar, ... DOI: https://doi. org/10.1101/2021.06 7, 0 | 2 | |
| Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics RP Wallace, KC Refvik, JT Antane, K Brünggel, AC Tremain, MR Raczy, ... Cell Reports Medicine 5 (1), 2024 | 1 | 2024 |
| Engineered collagen-targeting therapeutics reverse lung and kidney fibrosis in mice MJV White, MM Raczy, E Budina, E Yuba, A Solanki, HN Shim, ZJ Zhang, ... bioRxiv, 2022.01. 04.474747, 2022 | 1 | 2022 |
| A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice S Cao, E Budina, MM Raczy, A Solanki, M Nguyen, TN Beckman, ... Nature Biomedical Engineering, 1-17, 2024 | | 2024 |
| Thermoreversibly Assembled Polymersomes for Highly Efficient Loading, Processing, and Delivery of Protein and siRNA Biologics J Hubbell, S Hossainy, S Kang, JG Medellín, A Alpar, K Refvik, Y Ma, ... | | 2024 |
| Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia AJ Slezak, K Chang, TN Beckman, KC Refvik, AT Alpar, AL Lauterbach, ... Blood Advances, bloodadvances. 2023012529, 2024 | | 2024 |
| Engineered Flt3L Drives Tolerogenic State to Attenuate Anti-drug Antibody Responses AT Alpar, RP Wallace, KC Refvik, S Gomes, A Solanki, LT Gray, AJ Slezak, ... bioRxiv, 2024.03. 21.586168, 2024 | | 2024 |
| Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity S Kang, A Mansurov, T Kurtanich, HR Chun, AJ Slezak, LR Volpatti, ... Science Advances 9 (48), eadh9879, 2023 | | 2023 |
