Determinants of telomere length across human tissues K Demanelis, F Jasmine, LS Chen, M Chernoff, L Tong, D Delgado, ... Science 369 (6509), eaaz6876, 2020 | 303 | 2020 |
Comparison of telomere length measurement methods TP Lai, WE Wright, JW Shay Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 242 | 2018 |
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer W Kim, AT Ludlow, J Min, JD Robin, G Stadler, I Mender, TP Lai, N Zhang, ... PLoS biology 14 (12), e2000016, 2016 | 195 | 2016 |
A method for measuring the distribution of the shortest telomeres in cells and tissues TP Lai, N Zhang, J Noh, I Mender, E Tedone, E Huang, WE Wright, ... Nature communications 8 (1), 1356, 2017 | 139 | 2017 |
Regulation of tRNA Bidirectional Nuclear-Cytoplasmic Trafficking in Saccharomyces cerevisiae A Murthi, HH Shaheen, HY Huang, MA Preston, TP Lai, EM Phizicky, ... Molecular biology of the cell 21 (4), 639-649, 2010 | 125 | 2010 |
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer AT Ludlow, MS Wong, JD Robin, K Batten, L Yuan, TP Lai, N Dahlson, ... Nature communications 9 (1), 3112, 2018 | 78 | 2018 |
Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians E Tedone, E Huang, R O’Hara, K Batten, AT Ludlow, TP Lai, B Arosio, ... Aging Cell 18 (1), e12859, 2019 | 67 | 2019 |
Telomerase-mediated strategy for overcoming non–small cell lung cancer targeted therapy and chemotherapy resistance I Mender, R LaRanger, K Luitel, M Peyton, L Girard, TP Lai, K Batten, ... Neoplasia 20 (8), 826-837, 2018 | 54 | 2018 |
Telomere length tracking in children and their parents: implications for adult onset diseases A Benetos, S Verhulst, C Labat, TP Lai, N Girerd, S Toupance, F Zannad, ... The FASEB journal 33 (12), 14248, 2019 | 48 | 2019 |
The maintenance of telomere length in CD28+ T cells during T lymphocyte stimulation E Huang, E Tedone, R O’Hara, C Cornelius, TP Lai, A Ludlow, WE Wright, ... Scientific reports 7 (1), 6785, 2017 | 44 | 2017 |
Transient introduction of human telomerase mRNA improves hallmarks of progeria cells Y Li, G Zhou, IG Bruno, N Zhang, S Sho, E Tedone, TP Lai, JP Cooke, ... Aging Cell 18 (4), e12979, 2019 | 40 | 2019 |
Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency B Holohan, W Kim, TP Lai, H Hoshiyama, N Zhang, AM Alazami, ... BMC genomics 17, 79-87, 2016 | 39 | 2016 |
Measurement of telomere length for longitudinal analysis: implications of assay precision D Nettle, SM Gadalla, TP Lai, E Susser, M Bateson, A Aviv American Journal of Epidemiology 190 (7), 1406-1413, 2021 | 33 | 2021 |
Generation of digoxigenin-incorporated probes to enhance DNA detection sensitivity SJW Lai TP, Wright WE Biotechniques 60, 306-309, 2016 | 30 | 2016 |
The nexus between telomere length and lymphocyte count in seniors hospitalized with COVID-19 A Benetos, TP Lai, S Toupance, C Labat, S Verhulst, S Gautier, ... The Journals of Gerontology: Series A 76 (8), e97-e101, 2021 | 28 | 2021 |
Perifosine as a potential novel anti-telomerase therapy B Holohan, MM Hagiopian, TP Lai, E Huang, DR Friedman, WE Wright, ... Oncotarget 6 (26), 21816, 2015 | 19 | 2015 |
Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane TP Lai, KA Stauffer, A Murthi, HH Shaheen, G Peng, NC Martin, ... Traffic 10 (9), 1243-1256, 2009 | 18 | 2009 |
Time lapse to colorectal cancer: telomere dynamics define the malignant potential of polyps BR Druliner, X Ruan, R Johnson, D Grill, D O'brien, TP Lai, S Rashtak, ... Clinical and translational gastroenterology 7 (9), e188, 2016 | 14 | 2016 |
Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes TP Lai, M Simpson, K Patel, S Verhulst, J Noh, N Roche, D Heller, ... Scientific reports 11 (1), 5115, 2021 | 10 | 2021 |
A mechanism for severity of disease in older patients with COVID-19: the nexus between telomere length and lymphopenia A Benetos, TP Lai, S Toupance, C Labat, S Verhulst, S Gautier, ... medRxiv, 2020.10. 01.20205393, 2020 | 9 | 2020 |