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David Pincus
David Pincus
Verified email at uchicago.edu
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Year
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
N King, MJ Westbrook, SL Young, A Kuo, M Abedin, J Chapman, ...
Nature 451 (7180), 783-788, 2008
12102008
Endoplasmic reticulum stress sensing in the unfolded protein response
BM Gardner, D Pincus, K Gotthardt, CM Gallagher, P Walter
Cold Spring Harbor perspectives in biology 5 (3), a013169, 2013
8032013
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
D Pincus, MW Chevalier, T Aragón, E van Anken, SE Vidal, H El-Samad, ...
PLoS biology 8 (7), e1000415, 2010
4932010
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
T Aragón, E Van Anken, D Pincus, IM Serafimova, AV Korennykh, ...
Nature 457 (7230), 736-740, 2009
4302009
In silico feedback for in vivo regulation of a gene expression circuit
A Milias-Argeitis, S Summers, J Stewart-Ornstein, I Zuleta, D Pincus, ...
Nature biotechnology 29 (12), 1114-1116, 2011
3302011
Negative feedback that improves information transmission in yeast signalling
RC Yu, CG Pesce, A Colman-Lerner, L Lok, D Pincus, E Serra, M Holl, ...
Nature 456 (7223), 755-761, 2008
2622008
Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
X Zheng, J Krakowiak, N Patel, A Beyzavi, J Ezike, AS Khalil, D Pincus
elife 5, e18638, 2016
2212016
Lipidomic analysis of α-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment
S Fanning, A Haque, T Imberdis, V Baru, MI Barrasa, S Nuber, D Termine, ...
Molecular cell 73 (5), 1001-1014. e8, 2019
2202019
Defining the essential function of yeast Hsf1 reveals a compact transcriptional program for maintaining eukaryotic proteostasis
EJ Solís, JP Pandey, X Zheng, DX Jin, PB Gupta, EM Airoldi, D Pincus, ...
Molecular cell 63 (1), 60-71, 2016
1972016
Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
C Rubio, D Pincus, A Korennykh, S Schuck, H El-Samad, P Walter
Journal of Cell Biology 193 (1), 171-184, 2011
1802011
Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages
D Pincus, I Letunic, P Bork, WA Lim
Proceedings of the National Academy of Sciences 105 (28), 9680-9684, 2008
1622008
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response
J Krakowiak, X Zheng, N Patel, ZA Feder, J Anandhakumar, K Valerius, ...
Elife 7, e31668, 2018
1312018
Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness
BW Tye, N Commins, LV Ryazanova, M Wühr, M Springer, D Pincus, ...
elife 8, e43002, 2019
1052019
Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range
TM Thomson, KR Benjamin, A Bush, T Love, D Pincus, O Resnekov, ...
Proceedings of the National Academy of Sciences 108 (50), 20265-20270, 2011
922011
tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae
JR Damon, D Pincus, HL Ploegh
Molecular biology of the cell 26 (2), 270-282, 2015
792015
Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses
PM Fordyce, D Pincus, P Kimmig, CS Nelson, H El-Samad, P Walter, ...
Proceedings of the National Academy of Sciences 109 (45), E3084-E3093, 2012
712012
Translocon declogger Ste24 protects against IAPP oligomer-induced proteotoxicity
C Kayatekin, A Amasino, G Gaglia, J Flannick, JM Bonner, S Fanning, ...
Cell 173 (1), 62-73. e9, 2018
622018
m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis
GG Bushkin, D Pincus, JT Morgan, K Richardson, C Lewis, SH Chan, ...
Nature communications 10 (1), 3414, 2019
582019
Regulation of Hsf1 and the heat shock response
D Pincus
HSF1 and molecular chaperones in biology and cancer, 41-50, 2020
572020
Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome
D Pincus, J Anandhakumar, P Thiru, MJ Guertin, AM Erkine, DS Gross
Molecular Biology of the Cell 29 (26), 3168-3182, 2018
572018
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