| Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer W Kim, AT Ludlow, J Min, JD Robin, G Stadler, I Mender, TP Lai, N Zhang, ... PLoS biology 14 (12), e2000016, 2016 | 195 | 2016 |
| Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2′-deoxyguanosine I Mender, S Gryaznov, ZG Dikmen, WE Wright, JW Shay Cancer discovery 5 (1), 82-95, 2015 | 143 | 2015 |
| A method for measuring the distribution of the shortest telomeres in cells and tissues TP Lai, N Zhang, J Noh, I Mender, E Tedone, E Huang, WE Wright, ... Nature communications 8 (1), 1356, 2017 | 139 | 2017 |
| Telomerase repeated amplification protocol (TRAP) I Mender, JW Shay Bio-protocol 5 (22), e1657-e1657, 2015 | 86 | 2015 |
| Telomere stress potentiates STING-dependent anti-tumor immunity I Mender, A Zhang, Z Ren, C Han, Y Deng, S Siteni, H Li, J Zhu, A Vemula, ... Cancer cell 38 (3), 400-411. e6, 2020 | 82 | 2020 |
| NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer AT Ludlow, MS Wong, JD Robin, K Batten, L Yuan, TP Lai, N Dahlson, ... Nature communications 9 (1), 3112, 2018 | 78 | 2018 |
| Telomere restriction fragment (TRF) analysis I Mender, JW Shay Bio-protocol 5 (22), e1658-e1658, 2015 | 65 | 2015 |
| Telomerase-mediated strategy for overcoming non–small cell lung cancer targeted therapy and chemotherapy resistance I Mender, R LaRanger, K Luitel, M Peyton, L Girard, TP Lai, K Batten, ... Neoplasia 20 (8), 826-837, 2018 | 54 | 2018 |
| Induced telomere damage to treat telomerase expressing therapy-resistant pediatric brain tumors S Sengupta, M Sobo, K Lee, S Senthil Kumar, AR White, I Mender, ... Molecular cancer therapeutics 17 (7), 1504-1514, 2018 | 53 | 2018 |
| Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma P Reyes-Uribe, MP Adrianzen-Ruesta, Z Deng, I Echevarria-Vargas, ... Oncogene 37 (30), 4058-4072, 2018 | 50 | 2018 |
| Telomere dysfunction induced foci (TIF) analysis I Mender, JW Shay Bio-protocol 5 (22), e1656-e1656, 2015 | 37 | 2015 |
| A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells I Mender, S Gryaznov, JW Shay Oncoscience 2 (8), 693, 2015 | 37 | 2015 |
| Induction of telomere dysfunction prolongs disease control of therapy-resistant melanoma G Zhang, LW Wu, I Mender, M Barzily-Rokni, MR Hammond, O Ope, ... Clinical Cancer Research 24 (19), 4771-4784, 2018 | 35 | 2018 |
| Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton I Mender, S Senturk, N Ozgunes, K Akcali, D Kletsas, S Gryaznov, A Can, ... International journal of oncology 42 (5), 1709-1715, 2013 | 34 | 2013 |
| A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT GA Hosler, T Davoli, I Mender, B Litzner, J Choi, P Kapur, JW Shay, ... Journal of cutaneous pathology 42 (2), 108-117, 2015 | 12 | 2015 |
| A modified nucleoside 6-Thio-2′-deoxyguanosine exhibits antitumor activity in gliomas S Yu, S Wei, M Savani, X Lin, K Du, I Mender, S Siteni, T Vasilopoulos, ... Clinical Cancer Research 27 (24), 6800-6814, 2021 | 10 | 2021 |
| Proliferation of adult human bronchial epithelial cells without a telomere maintenance mechanism for over 200 population doublings JR Peters-Hall, J Min, E Tedone, S Sho, S Siteni, I Mender, JW Shay FASEB journal: official publication of the Federation of American Societies …, 2020 | 10 | 2020 |
| SLC43A3 Is a Biomarker of Sensitivity to the Telomeric DNA Damage Mediator 6-Thio-2′-Deoxyguanosine I Mender, K Batten, M Peyton, A Vemula, C Cornelius, L Girard, B Gao, ... Cancer research 80 (5), 929-936, 2020 | 9 | 2020 |
| Human lung epithelial cells divide> 200 population doublings without engaging a telomere maintenance mechanism JR Peters-Hall, J Min, E Tedone, S Sho, S Siteni, I Mender, JW Shay bioRxiv, 474270, 2018 | 6 | 2018 |
| How can I protect my telomeres and slow aging? ZG Dikmen, I Mender Turkish Journal of Biochemistry 42 (6), 587-590, 2017 | 5 | 2017 |
