Machine learning-guided engineering of genetically encoded fluorescent calcium indicators SJ Wait, M Expòsit, S Lin, M Rappleye, JD Lee, SA Colby, L Torp, ... Nature Computational Science, 1-13, 2024 | | 2024 |
The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility M Mahoney-Schaefer, KB Kooiker, S Mohran, GV Flint, M Regnier, ... Biophysical Journal 123 (3), 266a-267a, 2024 | | 2024 |
Estimating the effect of danicamtiv on human cardiac function SM Mijailovich, M Prodanovic, V Cvetkovic, A Grujic, M Regnier, ... Biophysical Journal 123 (3), 266a, 2024 | | 2024 |
Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations S Malingen, MC Childers, T Tune, KY Kao, TL Daniel, F Moussavi-Harami, ... Biophysical Journal 123 (3), 401a-402a, 2024 | | 2024 |
2-Deoxy-ATP reduces the cardiac depressive effect of acidosis MA Redd, TS McMillen, MK Woodward, S Mohran, KB Kooiker, GV Flint, ... Biophysical Journal 123 (3), 403a-404a, 2024 | | 2024 |
The biochemically defined super relaxed state of myosin—a paradox S Mohran, K Kooiker, M Mahoney-Schaefer, C Mandrycky, K Kao, AY Tu, ... Journal of Biological Chemistry 300 (1), 2024 | 3 | 2024 |
Echocardiography to Assess Cardiac Structure and Function in Genetic Cardiomyopathies G Flint, K Kooiker, F Moussavi-Harami Familial Cardiomyopathies: Methods and Protocols, 1-15, 2023 | | 2023 |
Danicamtiv increases myosin recruitment and alters cross-bridge cycling in cardiac muscle KB Kooiker, S Mohran, KL Turner, W Ma, A Martinson, G Flint, L Qi, C Gao, ... Circulation Research 133 (5), 430-443, 2023 | 4 | 2023 |
The Effects Of Cardiac Troponin Activator CK-358 On Cardiac Contractility In A Mouse Model Of Genetic Dilated Cardiomyopathy S Neys, K Kooiker, A Martinson, D Hwee, J Hartman, AN Murphy, ... CIRCULATION RESEARCH 133, 2023 | | 2023 |
Abstract EC. 04: The Effects Of Cardiac Troponin Activator CK-358 On Cardiac Contractility In A Mouse Model Of Genetic Dilated Cardiomyopathy S Neys, K Kooiker, A Martinson, D Hwee, J Hartman, AN Murphy, ... Circulation Research 133 (Suppl_1), AEC. 04-AEC. 04, 2023 | | 2023 |
Myofilament Function 2022: Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations A Asencio, S Malingen, KB Kooiker, JD Powers, J Davis, T Daniel, ... The Journal of General Physiology 155 (5), 2023 | | 2023 |
Cell based dATP delivery as a therapy for chronic heart failure KN Mhatre, J Mathieu, A Martinson, G Flint, LP Blakley, A Tabesh, ... bioRxiv, 2023 | 3 | 2023 |
Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations A Asencio, S Malingen, KB Kooiker, JD Powers, J Davis, T Daniel, ... Journal of General Physiology 155 (5), e202213291, 2023 | 1 | 2023 |
The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy KB Kooiker, S Mohran, M Mahoney-Schaefer, J Freeman, MA Geeves, ... Biophysical Journal 122 (3), 121a-122a, 2023 | | 2023 |
Elucidating the mechanism of Danicamtiv on force, kinetics, and myosin structure and function KB Kooiker, S Mohran, W Ma, GV Flint, KY Kao, L Qi, T McMillen, S Neys, ... Biophysical Journal 122 (3), 453a, 2023 | | 2023 |
Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle KB Kooiker, S Mohran, KL Turner, W Ma, G Flint, L Qi, C Gao, Y Zheng, ... bioRxiv, 2023.01. 31.526380, 2023 | 3 | 2023 |
dATP elevation induces myocardial metabolic remodeling to support improved cardiac function KN Mhatre, JD Murray, G Flint, TS McMillen, G Weber, M Shakeri, AY Tu, ... Journal of Molecular and Cellular Cardiology 175, 1-12, 2023 | 5 | 2023 |
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency RC Bretherton, IM Reichardt, KA Zabrecky, AJ Goldstein, LRJ Bailey, ... bioRxiv, 2023.01. 23.523684, 2023 | 3 | 2023 |
Late-life Rapamycin Treatment Enhances Cardiomyocyte Relaxation Kinetics and Reduces Myocardial Stiffness AD Chakraborty, K Kooiker, KA Kobak, Y Cheng, CF Lee, M Razumova, ... bioRxiv, 2023.06. 12.544619, 2023 | | 2023 |
Ribonucleotide reductase mediated regulation of mitochondrial activity in the adult heart M Shakeri, D Berisha, A Martinson, J Davis, F Moussavi-Harami Biophysical Journal 121 (3), 396a-397a, 2022 | 2 | 2022 |