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Akshayalakshmi Sridhar
Akshayalakshmi Sridhar
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Single-cell transcriptomic comparison of human fetal retina, hPSC-derived retinal organoids, and long-term retinal cultures
A Sridhar, A Hoshino, CR Finkbeiner, A Chitsazan, L Dai, AK Haugan, ...
Cell reports 30 (5), 1644-1659. e4, 2020
2022020
Three-dimensional retinal organoids facilitate the investigation of retinal ganglion cell development, organization and neurite outgrowth from human pluripotent stem cells
CM Fligor, KB Langer, A Sridhar, Y Ren, PK Shields, MC Edler, ...
Scientific reports 8 (1), 14520, 2018
1582018
Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration
JSM Sarah K. Ohlemacher, Akshayalakshmi Sridhar, Yucheng Xiao, Alexandra E ...
Stem Cells, 2016
1352016
Generation of highly enriched populations of optic vesicle− like retinal cells from human pluripotent stem cells
SK Ohlemacher, CL Iglesias, A Sridhar, DM Gamm, JS Meyer
Current protocols in stem cell biology 32 (1), 1H. 8.1-1H. 8.20, 2015
1002015
Neural regeneration
MM Steward, A Sridhar, JS Meyer
New perspectives in regeneration, 163-191, 2013
742013
Nonxenogeneic growth and retinal differentiation of human induced pluripotent stem cells
A Sridhar, MM Steward, JS Meyer
Stem cells translational medicine 2 (4), 255-264, 2013
682013
Robust differentiation of mRNA-reprogrammed human induced pluripotent stem cells toward a retinal lineage
A Sridhar, SK Ohlemacher, KB Langer, JS Meyer
Stem cells translational medicine 5 (4), 417-426, 2016
522016
Single-cell ATAC-seq of fetal human retina and stem-cell-derived retinal organoids shows changing chromatin landscapes during cell fate acquisition
C Finkbeiner, I Ortuño-Lizarán, A Sridhar, M Hooper, S Petter, TA Reh
Cell reports 38 (4), 2022
492022
Synchrony and asynchrony between an epigenetic clock and developmental timing.
ACTAR Akina Hoshino, Steve Horvath, Akshayalakshmi Sridhar
Scientific reports 9 (1), 3770, 2019
482019
Astrocytes regulate the development and maturation of retinal ganglion cells derived from human pluripotent stem cells
KB VanderWall, R Vij, SK Ohlemacher, A Sridhar, CM Fligor, EM Feder, ...
Stem cell reports 12 (2), 201-212, 2019
402019
Energy metabolism and mitochondrial superoxide anion production in pre-symptomatic striatal neurons derived from human-induced pluripotent stem cells expressing mutant Huntingtin
J Hamilton, T Brustovetsky, A Sridhar, Y Pan, TR Cummins, JS Meyer, ...
Molecular Neurobiology 57, 668-684, 2020
192020
A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration
LD Orozco, LA Owen, J Hofmann, AD Stockwell, J Tao, S Haller, ...
Cell genomics 3 (6), 2023
82023
Human pluripotent stem cells as in vitro models for retinal development and disease
A Sridhar, KB Langer, CM Fligor, M Steinhart, CA Miller, KT Ho-A-Lim, ...
Regenerative Medicine and Stem Cell Therapy for the Eye, 17-49, 2018
82018
Three-dimensional retinal organoids facilitate the investigation of retinal ganglion cell development, organization and neurite outgrowth from human pluripotent stem cells. Sci …
CM Fligor, KB Langer, A Sridhar, Y Ren, PK Shields, MC Edler
External Resources Crossref (DOI), 0
5
Single-cell sequencing of individual retinal organoids reveals determinants of cell-fate heterogeneity
A Tresenrider, A Sridhar, KC Eldred, S Cuschieri, D Hoffer, C Trapnell, ...
Cell Reports Methods 3 (8), 2023
32023
Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells
KB Langer, R Vij, SK Ohlemacher, A Sridhar, CM Fligor, EM Feder, ...
bioRxiv, 428631, 2018
2018
Extensive Axonal Outgrowth and Pathfinding from Retinal Ganglion Cells Derived From Human Pluripotent Stem Cells
C Fligor, A Sridhar, V Sluch, DJ Zack, D Suter, JS Meyer
Investigative Ophthalmology & Visual Science 58 (8), 1370-1370, 2017
2017
Analysis of Retinal Ganglion Cell Development and Maturation From Human Pluripotent Stem Cells
S Ohlemacher, A Sridhar, Y Xiao, A Baucum, T Cummins, JS Meyer
Investigative Ophthalmology & Visual Science 58 (8), 1369-1369, 2017
2017
Build your own retina: modeling retinogenesis and disease using human pluripotent stem cells
A Sridhar
Purdue University, 2017
2017
The role of SIX6 in the development of optic vesicle-like structures derived from human pluripotent stem cells
JA Cooke, A Sridhar, S Ohlemacher, JS Meyer
Investigative Ophthalmology & Visual Science 57 (12), 1134-1134, 2016
2016
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