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Accurate computational design of multipass transmembrane proteins P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ... Science 359 (6379), 1042-1046, 2018 | 169 | 2018 |
Computational design of self-assembling cyclic protein homo-oligomers JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ... Nature chemistry 9 (4), 353-360, 2017 | 154 | 2017 |
Computational design of self-assembling cyclic protein homo-oligomers JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ... Nature chemistry 9 (4), 353-360, 2017 | 154 | 2017 |
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens G Ueda, A Antanasijevic, JA Fallas, W Sheffler, J Copps, D Ellis, ... Elife 9, e57659, 2020 | 130 | 2020 |
Designed proteins assemble antibodies into modular nanocages R Divine, HV Dang, G Ueda, JA Fallas, I Vulovic, W Sheffler, S Saini, ... Science 372 (6537), eabd9994, 2021 | 116 | 2021 |
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ... Science 364 (6442), eaav7532, 2019 | 107 | 2019 |
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ... Science translational medicine 14 (646), eabn1252, 2022 | 70 | 2022 |
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens A Antanasijevic, G Ueda, PJM Brouwer, J Copps, D Huang, JD Allen, ... PLoS Pathogens 16 (8), e1008665, 2020 | 55 | 2020 |
Computational design of mechanically coupled axle-rotor protein assemblies A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ... Science 376 (6591), 383-390, 2022 | 43 | 2022 |
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations JT Martin, CA Cottrell, A Antanasijevic, DG Carnathan, BJ Cossette, ... npj Vaccines 5 (1), 72, 2020 | 42 | 2020 |
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Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines S Boyoglu-Barnum, D Ellis, RA Gillespie, GB Hutchinson, YJ Park, ... bioRxiv, 2020.05. 30.125179, 2020 | 28 | 2020 |
Multivalent designed proteins protect against SARS-CoV-2 variants of concern AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ... BioRxiv, 2021 | 15 | 2021 |
F‐domain valency determines outcome of signaling through the angiopoietin pathway YT Zhao, JA Fallas, S Saini, G Ueda, L Somasundaram, Z Zhou, ... EMBO reports 22 (12), e53471, 2021 | 14 | 2021 |
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera GB Hutchinson, OM Abiona, CT Ziwawo, AP Werner, D Ellis, Y Tsybovsky, ... Nature Communications 14 (1), 6195, 2023 | 5 | 2023 |
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De novo design of modular protein hydrogels with programmable intra-and extracellular viscoelasticity R Mout, RC Bretherton, J Decarreau, S Lee, N Gregorio, NI Edman, ... Proceedings of the National Academy of Sciences 121 (6), e2309457121, 2024 | 1 | 2024 |
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