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Christopher Donnelly
Christopher Donnelly
Associate Professor of Neurobiology, Scientific Director, Live Like Lou Center for ALS Research
Verified email at pitt.edu
Title
Cited by
Cited by
Year
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ...
Nature 525 (7567), 56-61, 2015
10162015
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ...
Neuron 80 (2), 415-428, 2013
10052013
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
JDRJW Aaron R. Haeusler, Christopher J. Donnelly, Goran
Nature, 2014
9982014
RNA binding antagonizes neurotoxic phase transitions of TDP-43
JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ...
Neuron 102 (2), 321-338. e8, 2019
3892019
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke
S Li, JJ Overman, D Katsman, SV Kozlov, CJ Donnelly, JL Twiss, RJ Giger, ...
Nature neuroscience 13 (12), 1496-1504, 2010
3542010
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease
AR Haeusler, CJ Donnelly, JD Rothstein
Nature Reviews Neuroscience 17 (6), 383-395, 2016
2292016
Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth
CJ Donnelly, M Park, M Spillane, S Yoo, A Pacheco, C Gomes, ...
Journal of Neuroscience 33 (8), 3311-3322, 2013
1942013
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity
CJ Donnelly, DE Willis, M Xu, C Tep, C Jiang, S Yoo, NC Schanen, ...
The EMBO journal 30 (22), 4665-4677, 2011
1742011
Concordant but varied phenotypes among Duchenne muscular dystrophy patient-specific myoblasts derived using a human iPSC-based model
IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ...
Cell reports 15 (10), 2301-2312, 2016
1642016
Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex
M Spillane, A Ketschek, CJ Donnelly, A Pacheco, JL Twiss, G Gallo
Journal of Neuroscience 32 (49), 17671-17689, 2012
1342012
Subcellular communication through RNA transport and localized protein synthesis
CJ Donnelly, M Fainzilber, JL Twiss
Traffic 11 (12), 1498-1505, 2010
1332010
A HuD‐ZBP1 ribonucleoprotein complex localizes GAP‐43 mRNA into axons through its 3′ untranslated region AU‐rich regulatory element
S Yoo, HH Kim, P Kim, CJ Donnelly, AL Kalinski, D Vuppalanchi, M Park, ...
Journal of neurochemistry 126 (6), 792-804, 2013
942013
Axonal localization of transgene mRNA in mature PNS and CNS neurons
DE Willis, M Xu, CJ Donnelly, C Tep, M Kendall, M Erenstheyn, ...
Journal of Neuroscience 31 (41), 14481-14487, 2011
892011
WNK kinases sense molecular crowding and rescue cell volume via phase separation
CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ...
Cell 185 (24), 4488-4506. e20, 2022
662022
Nucleocytoplasmic proteomic analysis uncovers eRF1 and nonsense-mediated decay as modifiers of ALS/FTD C9orf72 toxicity
JA Ortega, EL Daley, S Kour, M Samani, L Tellez, HS Smith, EA Hall, ...
Neuron 106 (1), 90-107. e13, 2020
652020
Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment
AM Haidet-Phillips, L Roybon, SK Gross, A Tuteja, CJ Donnelly, ...
Stem cells translational medicine 3 (5), 575-585, 2014
432014
RNA modulates physiological and neuropathological protein phase transitions
JR Mann, CJ Donnelly
Neuron 109 (17), 2663-2681, 2021
402021
The Cloning and Characterization of the Histone Acetyltransferase Human Homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 Is Essential for …
X Zhu, N Singh, C Donnelly, P Boimel, F Elefant
Genetics 175 (3), 1229-1240, 2007
382007
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
EN Anderson, AA Morera, S Kour, JD Cherry, N Ramesh, A Gleixner, ...
Elife 10, e67587, 2021
352021
Lysophosphatidic acid differentially regulates axonal mRNA translation through 5′ UTR elements
D Vuppalanchi, TT Merianda, C Donnelly, A Pacheco, G Williams, S Yoo, ...
Molecular and Cellular Neuroscience 50 (2), 136-146, 2012
352012
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