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Austin M. Gabel
Austin M. Gabel
Verified email at uw.edu
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Year
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ...
Cell 184 (15), 4032-4047. e31, 2021
1532021
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons
JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ...
Nature genetics 52 (1), 84-94, 2020
812020
Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
PCR Parrish, JD Thomas, AM Gabel, S Kamlapurkar, RK Bradley, ...
Cell reports 36 (9), 2021
682021
Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies
S Li, Y Simoni, S Zhuang, A Gabel, S Ma, J Chee, L Islas, A Cessna, ...
Proceedings of the National Academy of Sciences 118 (30), e2025570118, 2021
402021
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells
K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ...
Nature biotechnology 40 (7), 1103-1113, 2022
362022
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
A Vichas, AK Riley, NT Nkinsi, S Kamlapurkar, PCR Parrish, A Lo, F Duke, ...
Nature communications 12 (1), 4789, 2021
272021
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo
AM Gabel, AE Belleville, JD Thomas, SA McKellar, TR Nicholas, T Banjo, ...
Nature Communications 15 (1), 959, 2024
12024
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
JD Thomas, SX Lu, E De Neef, E Sabio, B Rousseau, M Gigoux, DA Knorr, ...
Cancer Research 83 (7_Supplement), 5742-5742, 2023
12023
Expanding cancer therapy options by leveraging synthetic lethal interactions between druggable paralogs
PC Parrish, JD Thomas, AM Gabel, S Kamlapurkar, RK Bradley, ...
Cancer Research 82 (12_Supplement), 2278-2278, 2022
2022
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