Pharmacologic modulation of RNA splicing enhances anti-tumor immunity SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cell 184 (15), 4032-4047. e31, 2021 | 153 | 2021 |
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ... Nature genetics 52 (1), 84-94, 2020 | 81 | 2020 |
Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome PCR Parrish, JD Thomas, AM Gabel, S Kamlapurkar, RK Bradley, ... Cell reports 36 (9), 2021 | 68 | 2021 |
Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies S Li, Y Simoni, S Zhuang, A Gabel, S Ma, J Chee, L Islas, A Cessna, ... Proceedings of the National Academy of Sciences 118 (30), e2025570118, 2021 | 40 | 2021 |
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ... Nature biotechnology 40 (7), 1103-1113, 2022 | 36 | 2022 |
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer A Vichas, AK Riley, NT Nkinsi, S Kamlapurkar, PCR Parrish, A Lo, F Duke, ... Nature communications 12 (1), 4789, 2021 | 27 | 2021 |
Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo AM Gabel, AE Belleville, JD Thomas, SA McKellar, TR Nicholas, T Banjo, ... Nature Communications 15 (1), 959, 2024 | 1 | 2024 |
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity JD Thomas, SX Lu, E De Neef, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cancer Research 83 (7_Supplement), 5742-5742, 2023 | 1 | 2023 |
Expanding cancer therapy options by leveraging synthetic lethal interactions between druggable paralogs PC Parrish, JD Thomas, AM Gabel, S Kamlapurkar, RK Bradley, ... Cancer Research 82 (12_Supplement), 2278-2278, 2022 | | 2022 |