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Shawn D. Walker
Shawn D. Walker
VP, Global Head of Synthetics CMC Development, Sanofi
Verified email at sanofi.com
Title
Cited by
Cited by
Year
Catalysts for Suzuki− Miyaura coupling processes: scope and studies of the effect of ligand structure
TE Barder, SD Walker, JR Martinelli, SL Buchwald
Journal of the American Chemical Society 127 (13), 4685-4696, 2005
21382005
A rationally designed universal catalyst for Suzuki–Miyaura coupling processes
SD Walker, TE Barder, JR Martinelli, SL Buchwald
Angewandte Chemie International Edition 43 (14), 1871-1876, 2004
11102004
Silicon directed ipso-substitution of polymer bound arylsilanes: preparation of biaryls via the Suzuki cross-coupling reaction
Y Han, SD Walker, RN Young
Tetrahedron Letters 37 (16), 2703-2706, 1996
1561996
Highly enantioselective hydrogenation of styrenes directed by 2′-hydroxyl groups
X Wang, A Guram, S Caille, J Hu, JP Preston, M Ronk, S Walker
Organic Letters 13 (7), 1881-1883, 2011
842011
Molecular complexity as a driver for chemical process innovation in the pharmaceutical industry
S Caille, S Cui, MM Faul, SM Mennen, JS Tedrow, SD Walker
The Journal of Organic Chemistry 84 (8), 4583-4603, 2019
652019
Highly selective rhodium-catalyzed conjugate addition reactions of 4-oxobutenamides
JL Zigterman, JCS Woo, SD Walker, JS Tedrow, CJ Borths, EE Bunel, ...
The Journal of Organic Chemistry 72 (23), 8870-8876, 2007
572007
Development of a scalable synthesis of a GPR40 receptor agonist
SD Walker, CJ Borths, E DiVirgilio, L Huang, P Liu, H Morrison, K Sugi, ...
Organic Process Research & Development 15 (3), 570-580, 2011
522011
Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids
S Cui, SD Walker, JCS Woo, CJ Borths, H Mukherjee, MJ Chen, MM Faul
Journal of the American Chemical Society 132 (2), 436-437, 2010
512010
Selective catalytic hydrogenation of nitro groups in the presence of activated heteroaryl halides
AJ Kasparian, C Savarin, AM Allgeier, SD Walker
The Journal of Organic Chemistry 76 (23), 9841-9844, 2011
402011
Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation
JCS Woo, S Cui, SD Walker, MM Faul
Tetrahedron 66 (26), 4730-4737, 2010
322010
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 3: manganese-catalyzed asymmetric Epoxidation, crystallization, and …
AJ Maloney, E Içten, G Capellades, MG Beaver, X Zhu, LR Graham, ...
Organic Process Research & Development 24 (10), 1891-1908, 2020
282020
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 1: CDI-promoted amide bond formation
E Içten, AJ Maloney, MG Beaver, DE Shen, X Zhu, LR Graham, ...
Organic Process Research & Development 24 (10), 1861-1875, 2020
272020
Development of a commercial process to prepare AMG 232 using a green ozonolysis–Pinnick tandem transformation
BM Cochran, MT Corbett, TL Correll, YQ Fang, TG Flick, SC Jones, ...
The Journal of Organic Chemistry 84 (8), 4763-4779, 2018
262018
Development of a suitable salt form for a GPR40 receptor agonist
H Morrison, J Jona, SD Walker, JCS Woo, L Li, J Fang
Organic Process Research & Development 15 (1), 104-111, 2011
252011
Rational Screening Approach for Classical Chiral Resolution under Thermodynamic Equilibrium: A Case Study of Diphenyl-Substituted N-Methyl-Piperazine
H Tan, S Cui, K Gahm, V Luu, SD Walker
Organic Process Research & Development 15 (1), 53-63, 2011
242011
Continuous process improvement in the manufacture of Carfilzomib, part 2: an improved process for synthesis of the Epoxyketone warhead
MG Beaver, X Shi, J Riedel, P Patel, A Zeng, MT Corbett, JA Robinson, ...
Organic Process Research & Development 24 (4), 490-499, 2020
222020
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 2: Enone synthesis via a Barbier-type Grignard process
E Içten, AJ Maloney, MG Beaver, X Zhu, DE Shen, JA Robinson, ...
Organic Process Research & Development 24 (10), 1876-1890, 2020
212020
A new cycloheptenone annulation method: use of the bifunctional reagent (Z)-5-iodo-1-tributylstannylpent-1-ene in organic synthesis
E Piers, SD Walker, R Armbrust
Journal of the Chemical Society, Perkin Transactions 1, 635-637, 2000
212000
Appearance of a new hydrated form during development: a case study in process and solid-state optimization
H Morrison, BP Quan, SD Walker, KB Hansen, K Nagapudi, S Cui
Organic Process Research & Development 19 (12), 1842-1848, 2015
192015
Practical Chromatography-Free Synthesis of 2-Iodo-N, N-diisopropylferrocenecarboxamide and Further Transformations
W Erb, T Roisnel, V Dorcet
Synthesis 51 (17), 3205-3213, 2019
172019
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