Catalysts for Suzuki− Miyaura coupling processes: scope and studies of the effect of ligand structure TE Barder, SD Walker, JR Martinelli, SL Buchwald Journal of the American Chemical Society 127 (13), 4685-4696, 2005 | 2138 | 2005 |
A rationally designed universal catalyst for Suzuki–Miyaura coupling processes SD Walker, TE Barder, JR Martinelli, SL Buchwald Angewandte Chemie International Edition 43 (14), 1871-1876, 2004 | 1110 | 2004 |
Silicon directed ipso-substitution of polymer bound arylsilanes: preparation of biaryls via the Suzuki cross-coupling reaction Y Han, SD Walker, RN Young Tetrahedron Letters 37 (16), 2703-2706, 1996 | 156 | 1996 |
Highly enantioselective hydrogenation of styrenes directed by 2′-hydroxyl groups X Wang, A Guram, S Caille, J Hu, JP Preston, M Ronk, S Walker Organic Letters 13 (7), 1881-1883, 2011 | 84 | 2011 |
Molecular complexity as a driver for chemical process innovation in the pharmaceutical industry S Caille, S Cui, MM Faul, SM Mennen, JS Tedrow, SD Walker The Journal of Organic Chemistry 84 (8), 4583-4603, 2019 | 65 | 2019 |
Highly selective rhodium-catalyzed conjugate addition reactions of 4-oxobutenamides JL Zigterman, JCS Woo, SD Walker, JS Tedrow, CJ Borths, EE Bunel, ... The Journal of Organic Chemistry 72 (23), 8870-8876, 2007 | 57 | 2007 |
Development of a scalable synthesis of a GPR40 receptor agonist SD Walker, CJ Borths, E DiVirgilio, L Huang, P Liu, H Morrison, K Sugi, ... Organic Process Research & Development 15 (3), 570-580, 2011 | 52 | 2011 |
Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids S Cui, SD Walker, JCS Woo, CJ Borths, H Mukherjee, MJ Chen, MM Faul Journal of the American Chemical Society 132 (2), 436-437, 2010 | 51 | 2010 |
Selective catalytic hydrogenation of nitro groups in the presence of activated heteroaryl halides AJ Kasparian, C Savarin, AM Allgeier, SD Walker The Journal of Organic Chemistry 76 (23), 9841-9844, 2011 | 40 | 2011 |
Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation JCS Woo, S Cui, SD Walker, MM Faul Tetrahedron 66 (26), 4730-4737, 2010 | 32 | 2010 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 3: manganese-catalyzed asymmetric Epoxidation, crystallization, and … AJ Maloney, E Içten, G Capellades, MG Beaver, X Zhu, LR Graham, ... Organic Process Research & Development 24 (10), 1891-1908, 2020 | 28 | 2020 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 1: CDI-promoted amide bond formation E Içten, AJ Maloney, MG Beaver, DE Shen, X Zhu, LR Graham, ... Organic Process Research & Development 24 (10), 1861-1875, 2020 | 27 | 2020 |
Development of a commercial process to prepare AMG 232 using a green ozonolysis–Pinnick tandem transformation BM Cochran, MT Corbett, TL Correll, YQ Fang, TG Flick, SC Jones, ... The Journal of Organic Chemistry 84 (8), 4763-4779, 2018 | 26 | 2018 |
Development of a suitable salt form for a GPR40 receptor agonist H Morrison, J Jona, SD Walker, JCS Woo, L Li, J Fang Organic Process Research & Development 15 (1), 104-111, 2011 | 25 | 2011 |
Rational Screening Approach for Classical Chiral Resolution under Thermodynamic Equilibrium: A Case Study of Diphenyl-Substituted N-Methyl-Piperazine H Tan, S Cui, K Gahm, V Luu, SD Walker Organic Process Research & Development 15 (1), 53-63, 2011 | 24 | 2011 |
Continuous process improvement in the manufacture of Carfilzomib, part 2: an improved process for synthesis of the Epoxyketone warhead MG Beaver, X Shi, J Riedel, P Patel, A Zeng, MT Corbett, JA Robinson, ... Organic Process Research & Development 24 (4), 490-499, 2020 | 22 | 2020 |
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 2: Enone synthesis via a Barbier-type Grignard process E Içten, AJ Maloney, MG Beaver, X Zhu, DE Shen, JA Robinson, ... Organic Process Research & Development 24 (10), 1876-1890, 2020 | 21 | 2020 |
A new cycloheptenone annulation method: use of the bifunctional reagent (Z)-5-iodo-1-tributylstannylpent-1-ene in organic synthesis E Piers, SD Walker, R Armbrust Journal of the Chemical Society, Perkin Transactions 1, 635-637, 2000 | 21 | 2000 |
Appearance of a new hydrated form during development: a case study in process and solid-state optimization H Morrison, BP Quan, SD Walker, KB Hansen, K Nagapudi, S Cui Organic Process Research & Development 19 (12), 1842-1848, 2015 | 19 | 2015 |
Practical Chromatography-Free Synthesis of 2-Iodo-N, N-diisopropylferrocenecarboxamide and Further Transformations W Erb, T Roisnel, V Dorcet Synthesis 51 (17), 3205-3213, 2019 | 17 | 2019 |