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Joao Siffert
Joao Siffert
President and CEO, Design Therapeutics
Verified email at designtx.com - Homepage
Title
Cited by
Cited by
Year
Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial
WJ Marks, RT Bartus, J Siffert, CS Davis, A Lozano, N Boulis, J Vitek, ...
The Lancet Neurology 9 (12), 1164-1172, 2010
7162010
Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
RT Bartus, TL Baumann, J Siffert, CD Herzog, R Alterman, N Boulis, ...
Neurology 80 (18), 1698-1701, 2013
2232013
A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease
MS Rafii, TL Baumann, RAE Bakay, JM Ostrove, J Siffert, AS Fleisher, ...
Alzheimer's & Dementia 10 (5), 571-581, 2014
2202014
Effect of dextromethorphan-quinidine on agitation in patients with Alzheimer disease dementia: a randomized clinical trial
JL Cummings, CG Lyketsos, ER Peskind, AP Porsteinsson, JE Mintzer, ...
Jama 314 (12), 1242-1254, 2015
1982015
Pharmacology of dextromethorphan: Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use
CP Taylor, SF Traynelis, J Siffert, LE Pope, RR Matsumoto
Pharmacology & therapeutics 164, 170-182, 2016
1802016
Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): differences between Parkinson's disease and nonhuman primate brains
RT Bartus, CD Herzog, Y Chu, A Wilson, L Brown, J Siffert, EM Johnson Jr, ...
Movement Disorders 26 (1), 27-36, 2011
1772011
Adeno-associated viral vector (serotype 2)–nerve growth factor for patients with alzheimer disease: a randomized clinical trial
MS Rafii, MH Tuszynski, RG Thomas, D Barba, JB Brewer, RA Rissman, ...
JAMA neurology 75 (7), 834-841, 2018
1692018
Hemorrhagic vasculopathy after treatment of central nervous system neoplasia in childhood: diagnosis and follow-up.
TY Poussaint, J Siffert, PD Barnes, SL Pomeroy, LC Goumnerova, ...
American journal of neuroradiology 16 (4), 693-699, 1995
1341995
Foreign body reaction to hemostatic materials mimicking recurrent brain tumor: Report of three cases
KF Kothbauer, GI Jallo, J Siffert, E Jimenez, JC Allen, FJ Epstein
Journal of neurosurgery 95 (3), 503-506, 2001
1242001
Neurological dysfunction associated with postoperative cerebellar mutism
J Siffert, T Young Poussaint, LC Goumnerova, RM Scott, B LaValley, ...
Journal of neuro-oncology 48, 75-81, 2000
1202000
Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of agitation in dementia
J Siffert, J Berg
US Patent App. 14/853,832, 2016
1122016
AVP‐825 breath‐powered intranasal delivery system containing 22 mg sumatriptan powder vs 100 mg oral sumatriptan in the acute treatment of migraines (The COMPASS study): A …
SJ Tepper, RK Cady, S Silberstein, J Messina, RA Mahmoud, ...
Headache: The Journal of Head and Face Pain 55 (5), 621-635, 2015
882015
A phase I/II study of carboplatin combined with hyperfractionated radiotherapy for brainstem gliomas
J Allen, J Siffert, B Donahue, A Nirenberg, R Jakacki, P Robertson, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 1999
881999
Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease
RT Bartus, L Brown, A Wilson, B Kruegel, J Siffert, EM Johnson Jr, ...
Neurobiology of disease 44 (1), 38-52, 2011
792011
Clinical manifestations of childhood ependymoma: a multitude of syndromes
JC Allen, J Siffert, J Hukin
Pediatric neurosurgery 28 (1), 49-55, 1998
771998
Neurokinin‐1‐receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study
K Tillisch, J Labus, B Nam, J Bueller, S Smith, B Suyenobu, J Siffert, ...
Alimentary pharmacology & therapeutics 35 (3), 360-367, 2012
592012
Leptomeningeal dissemination in children with progressive low-grade neuroepithelial tumors
J Hukin, J Siffert, L Velasquez, D Zagzag, J Allen
Neuro-oncology 4 (4), 253-260, 2002
572002
Contemporary chemotherapy issues for children with brainstem gliomas
JC Allen, J Siffert
Pediatric neurosurgery 24 (2), 98-102, 1996
521996
Patterns of recurrence in brain stem gliomas: evidence for craniospinal dissemination
B Donahue, J Allen, J Siffert, M Rosovsky, R Pinto
International Journal of Radiation Oncology* Biology* Physics 40 (3), 677-680, 1998
471998
Dose-intensive, time-compressed procarbazine, CCNU, vincristine (PCV) with peripheral blood stem cell support and concurrent radiation in patients with newly diagnosed high …
RI Jakacki, J Siffert, C Jamison, L Velasquez, JC Allen
Journal of neuro-oncology 44, 77-83, 1999
401999
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