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Prashanth Gokare
Prashanth Gokare
Janssen R&D
Verified email at yale.edu
Title
Cited by
Cited by
Year
Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures
NK Finnberg, P Gokare, A Lev, SI Grivennikov, AW MacFarlane IV, ...
Oncotarget 8 (40), 66747, 2017
1182017
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy
E Miller, HJ Lee, A Lulla, L Hernandez, P Gokare, B Lim
F1000Research 3, 2014
1072014
Sorafenib and quinacrine target anti-apoptotic protein MCL1: a poor prognostic marker in anaplastic thyroid cancer (ATC)
J Abdulghani, P Gokare, JN Gallant, D Dicker, T Whitcomb, T Cooper, ...
Clinical Cancer Research 22 (24), 6192-6203, 2016
412016
Inducible de novo expression of neoantigens in tumor cells and mice
Nature Biotechnology, 2020
38*2020
P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting
P Gokare, NK Finnberg, PH Abbosh, J Dai, ME Murphy, WS El-Deiry
Scientific Reports 7 (1), 9711, 2017
282017
Agonists of the TRAIL death receptor DR5 sensitize intestinal stem cells to chemotherapy-induced cell death and trigger gastrointestinal toxicity
NK Finnberg, P Gokare, A Navaraj, KA Lang Kuhs, G Cerniglia, H Yagita, ...
Cancer research 76 (3), 700-712, 2016
192016
PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features
EK Teye, A Sido, P Xin, NK Finnberg, P Gokare, YI Kawasawa, ...
Oncotarget 8 (18), 29887, 2017
132017
Novel and emerging targeted therapies of colorectal cancer
N Finnberg, P Gokare, W S El-Deiry
Current Clinical Pharmacology 10 (4), 279-298, 2015
62015
Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons
P Gokare, A Navaraj, S Zhang, N Motoyama, SS Sung, NK Finnberg
Oncotarget 7 (20), 29520, 2016
52016
Bcl-2 Protein Targeting by the p53/p21 Complex
LJ Hernandez Borrero, R Sikder, A Lulla, P Gokare, PR Del Valle, X Tian, ...
Cancer Research 78 (10), 2770-2771, 2018
42018
MMR-deficiency and BRCA2/EGFR/NTRK mutations
P Gokare, AR Lulla, WS El-Deiry
Aging (Albany NY) 9 (8), 1849, 2017
42017
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy. F1000Research, 3, 198
E Miller, HJ Lee, A Lulla, L Hernandez, P Gokare, B Lim
42014
Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers
YR Bhandari, V Krishna, R Powers, S Parmar, SJ Thursby, E Gupta, ...
Proceedings of the National Academy of Sciences 120 (31), e2301536120, 2023
12023
The tuberous sclerosis complex gets fatter
P Gokare, WS El-Deiry
Oncotarget 8 (26), 41780, 2017
12017
DR5-targeting sensitizes Lgr5+ stem cells to p53 and Chk2-dependent chemotherapy-induced cell death and produces dose-limiting gastrointestinal toxicity (GIT)
NK Finnberg, P Gokare, A Navaraj, KA Lang Kuhs, G Cerniglia, H Yagita, ...
Cancer Research 75 (15_Supplement), 2926-2926, 2015
12015
Development of organoids-bacteria co-cultures for medium-to-high throughput screening
E Valle-Encinas, M Doorn, F Pourfarzad, LS Mateo, P Gokare, D Pocalyko, ...
Cancer Research 84 (6_Supplement), 242-242, 2024
2024
Development of a medium-to-high throughput organoid-bacteria co-culture platform for the assessment of host pathogen interaction
E Valle-Encinas, R Nair, K Pisa, M Doorn, F Pourfarzad, LS Mateo, ...
Cancer Research 83 (7_Supplement), 5917-5917, 2023
2023
Identification of therapeutic vulnerabilities by genome-wide CRISPR knockout library screening of colon cancer organoids
PJ Buckhaults, S Khalili, C Banister, PR Gokare, D Pocalyko, K Bachman
Cancer Research 83 (7_Supplement), 251-251, 2023
2023
Abstract A012: Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers
YR Bhandari, V Krishna, R Powers, S Parmar, SJ Thursby, E Gupta, ...
Cancer Research 82 (23_Supplement_2), A012-A012, 2022
2022
Aurora kinase is synthetic lethal with APC loss of function in engineered human colon organoid models
DS Gaffney, E Vesely, D Pocalyko, K Bachman, K Wiehagen, G Cowley, ...
Cancer Research 82 (12_Supplement), 1416-1416, 2022
2022
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