RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2 M Chen, L Wei, CT Law, FHC Tsang, J Shen, CLH Cheng, LH Tsang, ... Hepatology 67 (6), 2254-2270, 2018 | 1069 | 2018 |
Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma DKC Chiu, APW Tse, IMJ Xu, J Di Cui, RKH Lai, LL Li, HY Koh, ... Nature communications 8 (1), 517, 2017 | 357 | 2017 |
Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma CCL Wong, APW Tse, YP Huang, YT Zhu, DKC Chiu, RKH Lai, SLK Au, ... Hepatology 60 (5), 1645-1658, 2014 | 273 | 2014 |
Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC L Wei, D Lee, CT Law, MS Zhang, J Shen, DWC Chin, A Zhang, ... Nature communications 10 (1), 4681, 2019 | 271 | 2019 |
Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26 DKC Chiu, IMJ Xu, RKH Lai, APW Tse, LL Wei, HY Koh, LL Li, D Lee, ... Hepatology 64 (3), 797-813, 2016 | 206 | 2016 |
Up‐regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis CM Wong, L Wei, CT Law, DWH Ho, FHC Tsang, SLK Au, KMF Sze, ... Hepatology 63 (2), 474-487, 2016 | 157 | 2016 |
Long non‐coding RNA HOTTIP is frequently up‐regulated in hepatocellular carcinoma and is targeted by tumour suppressive miR‐125b FHC Tsang, SLK Au, L Wei, DNY Fan, JMF Lee, CCL Wong, IOL Ng, ... Liver International 35 (5), 1597-1606, 2015 | 151 | 2015 |
Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3 L Wei, DKC Chiu, FHC Tsang, CT Law, CLH Cheng, SLK Au, JMF Lee, ... Journal of hepatology 67 (4), 758-769, 2017 | 139 | 2017 |
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma D Lee, IMJ Xu, DKC Chiu, RKH Lai, APW Tse, LL Li, CT Law, FHC Tsang, ... The Journal of clinical investigation 127 (5), 1856-1872, 2017 | 122 | 2017 |
Hepatocellular carcinoma cells up-regulate PVRL1, stabilizing PVR and inhibiting the cytotoxic T-cell response via TIGIT to mediate tumor resistance to PD1 inhibitors in mice DKC Chiu, VWH Yuen, JWS Cheu, LL Wei, V Ting, M Fehlings, ... Gastroenterology 159 (2), 609-623, 2020 | 117 | 2020 |
(−)-Epigallocatechin-3-gallate blocks 3T3-L1 adipose conversion by inhibition of cell proliferation and suppression of adipose phenotype expression CY Chan, L Wei, F Castro-Muñozledo, WL Koo Life sciences 89 (21-22), 779-785, 2011 | 116 | 2011 |
Histone lysine methyltransferase, suppressor of variegation 3‐9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA‐125b D Ngo‐Yin Fan, F Ho‐Ching Tsang, A Hoi‐Kam Tam, S Leung‐Kuen Au, ... Hepatology 57 (2), 637-647, 2013 | 111 | 2013 |
Aberrant super‐enhancer landscape in human hepatocellular carcinoma FHC Tsang, CT Law, TCC Tang, CLH Cheng, DWC Chin, WSV Tam, ... Hepatology 69 (6), 2502-2517, 2019 | 96 | 2019 |
MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis CM Wong, L Wei, SLK Au, DNY Fan, Y Zhou, FHC Tsang, CT Law, ... Oncotarget 6 (15), 13658, 2015 | 94 | 2015 |
Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis CCL Wong, SLK Au, APW Tse, IMJ Xu, RKH Lai, DKC Chiu, LL Wei, ... PloS one 9 (12), e115036, 2014 | 82 | 2014 |
HELLS regulates chromatin remodeling and epigenetic silencing of multiple tumor suppressor genes in human hepatocellular carcinoma CT Law, L Wei, FHC Tsang, CYK Chan, IMJ Xu, RKH Lai, DWH Ho, ... Hepatology 69 (5), 2013-2030, 2019 | 75 | 2019 |
NDUFA4L2 fine-tunes oxidative stress in hepatocellular carcinoma RKH Lai, IMJ Xu, DKC Chiu, APW Tse, LL Wei, CT Law, D Lee, CM Wong, ... Clinical Cancer Research 22 (12), 3105-3117, 2016 | 71 | 2016 |
Proteomic characterization of the cellular response to chemopreventive triterpenoid astragaloside IV in human hepatocellular carcinoma cell line HepG2 H Qi, L Wei, Y Han, Q Zhang, ASY Lau, J Rong International journal of oncology 36 (3), 725-735, 2010 | 69 | 2010 |
MicroRNA-142-3p and microRNA-142-5p are downregulated in hepatocellular carcinoma and exhibit synergistic effects on cell motility FHC Tsang, SLK Au, L Wei, DNY Fan, JMF Lee, CCL Wong, IOL Ng, ... Frontiers of Medicine 9, 331-343, 2015 | 60 | 2015 |
Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression J Shen, M Chen, D Lee, CT Law, L Wei, FHC Tsang, DWC Chin, ... Gut 69 (2), 329-342, 2020 | 43 | 2020 |