| Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis K Tsujita, S Suetsugu, N Sasaki, M Furutani, T Oikawa, T Takenawa The Journal of cell biology 172 (2), 269-279, 2006 | 436 | 2006 |
| PtdIns (3, 4, 5) P3 binding is necessary for WAVE2-induced formation of lamellipodia T Oikawa, H Yamaguchi, T Itoh, M Kato, T Ijuin, D Yamazaki, S Suetsugu, ... Nature cell biology 6 (5), 420-426, 2004 | 282 | 2004 |
| Sequential signals toward podosome formation in NIH-src cells T Oikawa, T Itoh, T Takenawa The Journal of cell biology 182 (1), 157-169, 2008 | 245 | 2008 |
| Optimization of WAVE2 complex–induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac S Suetsugu, S Kurisu, T Oikawa, D Yamazaki, A Oda, T Takenawa The Journal of cell biology 173 (4), 571-585, 2006 | 213 | 2006 |
| The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation S Suetsugu, K Murayama, A Sakamoto, K Hanawa-Suetsugu, A Seto, ... Journal of Biological Chemistry 281 (46), 35347-35358, 2006 | 208 | 2006 |
| Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion D Yamazaki, T Oikawa, T Takenawa Journal of cell science 120 (1), 86-100, 2007 | 161 | 2007 |
| Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion T Oikawa, M Oyama, H Kozuka-Hata, S Uehara, N Udagawa, H Saya, ... Journal of Cell Biology 197 (4), 553-568, 2012 | 116 | 2012 |
| ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer S Hashimoto, S Furukawa, A Hashimoto, A Tsutaho, A Fukao, ... Proceedings of the National Academy of Sciences 116 (35), 17450-17459, 2019 | 110 | 2019 |
| Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer S Hashimoto, S Mikami, H Sugino, A Yoshikawa, A Hashimoto, ... Nature communications 7 (1), 10656, 2016 | 102 | 2016 |
| Membrane lipids in invadopodia and podosomes: key structures for cancer invasion and metastasis H Yamaguchi, T Oikawa Oncotarget 1 (5), 320, 2010 | 99 | 2010 |
| P53-and mevalonate pathway–driven malignancies require Arf6 for metastasis and drug resistance A Hashimoto, T Oikawa, S Hashimoto, H Sugino, A Yoshikawa, Y Otsuka, ... Journal of cell biology 213 (1), 81-95, 2016 | 60 | 2016 |
| Regulation of osteoclasts by membrane-derived lipid mediators T Oikawa, Y Kuroda, K Matsuo Cellular and molecular life sciences 70, 3341-3353, 2013 | 50 | 2013 |
| ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance SH Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, Oikawa T Oncogenesis 5 (9), e259, 2016 | 45 | 2016 |
| Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion T Oikawa, A Nakamura, N Onishi, T Yamada, K Matsuo, H Saya Cancer research 73 (16), 5100-5109, 2013 | 40 | 2013 |
| PtdIns (3, 4) P2 instigates focal adhesions to generate podosomes T Oikawa, T Takenawa Cell adhesion & migration 3 (2), 195-197, 2009 | 34 | 2009 |
| High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue Y Otsuka, H Sato, T Oikawa, Y Onodera, JM Nam, A Hashimoto, ... Cell Communication and Signaling 14, 1-9, 2016 | 27 | 2016 |
| IRSp53 mediates podosome formation via VASP in NIH-Src cells T Oikawa, H Okamura, F Dietrich, Y Senju, T Takenawa, S Suetsugu PloS one 8 (3), e60528, 2013 | 25 | 2013 |
| Possible role of IRTKS in Tks5-driven osteoclast fusion T Oikawa, K Matsuo Communicative & integrative biology 5 (5), 511-515, 2012 | 19 | 2012 |
| p53-dependent and-independent epithelial integrity: beyond miRNAs and metabolic fluctuations T Oikawa, Y Otsuka, H Sabe Cancers 10 (6), 162, 2018 | 16 | 2018 |
| Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity T Oikawa, Y Otsuka, Y Onodera, M Horikawa, H Handa, S Hashimoto, ... Scientific reports 8 (1), 1595, 2018 | 14 | 2018 |
