Maximal activation of transcription by Statl and Stat3 requires both tyrosine and serine phosphorylation Z Wen, Z Zhong, JE Darnell Jr Cell 82 (2), 241-250, 1995 | 2531 | 1995 |
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 Z Zhong, Z Wen, JE Darnell Jr Science 264 (5155), 95-98, 1994 | 2507 | 1994 |
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors N Stahl, TJ Farruggella, TG Boulton, Z Zhong, JE Darnell Jr, ... Science 267 (5202), 1349-1353, 1995 | 1283 | 1995 |
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat) 3 and Stat4. NG Jacobson, SJ Szabo, RM Weber-Nordt, Z Zhong, RD Schreiber, ... The Journal of experimental medicine 181 (5), 1755-1762, 1995 | 870 | 1995 |
Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Z Zhong, Z Wen, JE Darnell Jr Proceedings of the National Academy of Sciences 91 (11), 4806-4810, 1994 | 591 | 1994 |
A mammalian factor that binds telomeric TTAGGG repeats in vitro Z Zhong, L Shiue, S Kaplan, T de Lange Molecular and cellular biology 12 (11), 4834-4843, 1992 | 421 | 1992 |
SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity H Yang, W Zhang, H Pan, HG Feldser, E Lainez, C Miller, S Leung, ... Public Library of Science 7 (9), e46364, 2012 | 338 | 2012 |
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms S Xiao, N Yosef, J Yang, Y Wang, L Zhou, C Zhu, C Wu, E Baloglu, ... Immunity 40 (4), 477-489, 2014 | 310 | 2014 |
Distribution of the mammalian Stat gene family in mouse chromosomes NG Copeland, DJ Gilbert, C Schindler, Z Zhong, Z Wen, JE Darnell Jr, ... Genomics 29 (1), 225-228, 1995 | 302 | 1995 |
STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase. TG Boulton, Z Zhong, Z Wen, JE Darnell Jr, N Stahl, GD Yancopoulos Proceedings of the National Academy of Sciences 92 (15), 6915-6919, 1995 | 246 | 1995 |
Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130: II. Src homology SH2 domains … U Hemmann, C Gerhartz, B Heesel, J Sasse, G Kurapkat, J Grötzinger, ... Journal of Biological Chemistry 271 (22), 12999-13007, 1996 | 245 | 1996 |
Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver. S Ruff-Jamison, Z Zhong, Z Wen, K Chen, JE Darnell, S Cohen Journal of Biological Chemistry 269 (35), 21933-21935, 1994 | 192 | 1994 |
An improved resazurin-based cytotoxicity assay for hepatic cells MK McMillian, L Li, JB Parker, L Patel, Z Zhong, JW Gunnett, WJ Powers, ... Cell biology and toxicology 18, 157-173, 2002 | 141 | 2002 |
In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3. AM Gronowski, Z Zhong, Z Wen, MJ Thomas, JE Darnell Jr, P Rotwein Molecular Endocrinology 9 (2), 171-177, 1995 | 138 | 1995 |
Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events X Xu, Y Lei, J Luo, J Wang, S Zhang, XJ Yang, M Sun, E Nuwaysir, G Fan, ... Stem cell research 10 (2), 213-227, 2013 | 137 | 2013 |
STAT signaling is active during early mammalian development SA Duncan, Z Zhong, Z Wen, JE Darnell Jr Developmental dynamics: an official publication of the American Association …, 1997 | 129 | 1997 |
Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis MK McMillian, ER Grant, Z Zhong, JB Parker, L Li, RA Zivin, ... In Vitro & Molecular Toxicology: A Journal of Basic and Applied Research 14 …, 2001 | 120 | 2001 |
Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon γ. TK Sengupta, A Chen, Z Zhong, JE Darnell Jr, LB Ivashkiv The Journal of experimental medicine 181 (3), 1015-1025, 1995 | 89 | 1995 |
Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory … F Wang, TK Sengupta, Z Zhong, LB Ivashkiv The Journal of experimental medicine 182 (6), 1825-1831, 1995 | 85 | 1995 |
Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells X Xu, Z Zhong Acta Pharmacologica Sinica 34 (6), 755-764, 2013 | 76 | 2013 |