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Xuyu Tan
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Light-triggered, self-immolative nucleic acid-drug nanostructures
X Tan, BB Li, X Lu, F Jia, C Santori, P Menon, H Li, B Zhang, JJ Zhao, ...
Journal of the American Chemical Society 137 (19), 6112-6115, 2015
2012015
Blurring the role of oligonucleotides: spherical nucleic acids as a drug delivery vehicle
X Tan, X Lu, F Jia, X Liu, Y Sun, JK Logan, K Zhang
Journal of the American Chemical Society 138 (34), 10834-10837, 2016
1542016
Molecular spherical nucleic acids
H Li, B Zhang, X Lu, X Tan, F Jia, Y Xiao, Z Cheng, Y Li, DO Silva, ...
Proceedings of the National Academy of Sciences 115 (17), 4340-4344, 2018
1142018
Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD
BLP G Zhang, P Sebastian, AR Loftis, X Tan, A Loas
BioRxiv, 2020
952020
Providing oligonucleotides with steric selectivity by brush-polymer-assisted compaction
X Lu, TH Tran, F Jia, X Tan, S Davis, S Krishnan, MM Amiji, K Zhang
Journal of the American Chemical Society 137 (39), 12466-12469, 2015
952015
Nucleic acid-based drug delivery strategies
X Tan, F Jia, P Wang, K Zhang
Journal of controlled release 323, 240-252, 2020
752020
Polycondensation of polymer brushes via DNA hybridization
X Lu, E Watts, F Jia, X Tan, K Zhang
Journal of the American Chemical Society 136 (29), 10214-10217, 2014
622014
Bottlebrush-architectured poly (ethylene glycol) as an efficient vector for RNA interference in vivo
D Wang, J Lin, F Jia, X Tan, Y Wang, X Sun, X Cao, F Che, H Lu, X Gao, ...
Science Advances 5 (2), eaav9322, 2019
602019
Effective antisense gene regulation via noncationic, polyethylene glycol brushes
X Lu, F Jia, X Tan, D Wang, X Cao, J Zheng, K Zhang
Journal of the American Chemical Society 138 (29), 9097-9100, 2016
552016
Effect of PEG architecture on the hybridization thermodynamics and protein accessibility of PEGylated oligonucleotides
F Jia, X Lu, X Tan, D Wang, X Cao, K Zhang
Angewandte Chemie 129 (5), 1259-1263, 2017
502017
Depth-profiling the nuclease stability and the gene silencing efficacy of brush-architectured poly (ethylene glycol)–DNA conjugates
F Jia, X Lu, D Wang, X Cao, X Tan, H Lu, K Zhang
Journal of the American Chemical Society 139 (31), 10605-10608, 2017
472017
Self-immolative polymers in biomedicine
Y Xiao, X Tan, Z Li, K Zhang
Journal of Materials Chemistry B 8 (31), 6697-6709, 2020
402020
Modulating the depolymerization of self-immolative brush polymers with poly (benzyl ether) backbones
Y Xiao, H Li, B Zhang, Z Cheng, Y Li, X Tan, K Zhang
Macromolecules 51 (8), 2899-2905, 2018
392018
Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly
F Jia, X Lu, X Tan, K Zhang
Chemical communications 51 (37), 7843-7846, 2015
342015
Precision tuning of DNA-and poly (ethylene glycol)-based nanoparticles via coassembly for effective antisense gene regulation
D Wang, X Lu, F Jia, X Tan, X Sun, X Cao, F Wai, C Zhang, K Zhang
Chemistry of materials: a publication of the American Chemical Society 29 …, 2017
312017
Expanding the Materials Space of DNA via Organic-Phase Ring-Opening Metathesis Polymerization
X Tan, H Lu, Y Sun, X Chen, D Wang, F Jia, K Zhang
Chem 5 (6), 1584-1596, 2019
292019
Spherical nucleic acids for topical treatment of hyperpigmentation
Y Fang, X Lu, D Wang, J Cai, Y Wang, P Chen, M Ren, H Lu, J Union, ...
Journal of the American Chemical Society 143 (3), 1296-1300, 2021
262021
Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer‐Assisted Compaction
X Cao, X Lu, D Wang, F Jia, X Tan, M Corley, X Chen, K Zhang
Small 13 (43), 1701432, 2017
262017
Self-assembled DNA–PEG bottlebrushes enhance antisense activity and pharmacokinetics of oligonucleotides
Y Wang, D Wang, F Jia, A Miller, X Tan, P Chen, L Zhang, H Lu, Y Fang, ...
ACS applied materials & interfaces 12 (41), 45830-45837, 2020
192020
Improving the enzymatic stability and the pharmacokinetics of oligonucleotides via DNA-backboned bottlebrush polymers
F Jia, D Wang, X Lu, X Tan, Y Wang, H Lu, K Zhang
Nano letters 18 (11), 7378-7382, 2018
152018
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