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Brian Kraemer
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Year
MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons
H Xu, Q Qiu, P Hu, K Hoxha, E Jang, M O’Reilly, C Kim, Z He, N Marotta, ...
Acta Neuropathologica 147 (1), 55, 2024
2024
Transgenic Dendra2:: tau expression allows in vivo monitoring of tau proteostasis in Caenorhabditis elegans
M Han, A Saxton, H Currey, SM Waldherr, NF Liachko, BC Kraemer
Disease Models & Mechanisms 17 (3), 2024
2024
Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets
VS Jadhav, JG Stair, RJ Eck, SN Smukowski, HN Currey, LG Toscano, ...
Neurobiology of Disease, 106441, 2024
12024
Perineuronal net deglycosylation associates with tauopathy‐induced gliosis and neurodegeneration
AF Logsdon, B Foresi, SJ Hu, E Quah, CJ Meuret, JP Le, AS Hendrickson, ...
Journal of Neurochemistry, 2024
22024
Compositions and methods for suppressing msutz
B Kraemer, JM Wheeler, P McMillan, TJ Strovas, J Baker
US Patent App. 18/038,307, 2024
2024
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal …
RJ Eck, JG Stair, BC Kraemer, NF Liachko
Frontiers in Neuroscience 17, 1300705, 2024
2024
Deglycosylation of perineuronal nets in mouse models of tauopathy
KM Alonge, B Foresi, S Hu, A Hendrickson, IK Redford, A Kumar, E Quah, ...
GLYCOBIOLOGY 33 (11), 970-970, 2023
2023
PSEN2 poison exon inclusion is common across brain regions in late‐onset Alzheimer’s disease
MM Course, J Somberg, DD Child, K Gudsnuk, CS Latimer, BC Kraemer, ...
Alzheimer's & Dementia 19, e073966, 2023
2023
Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change
PJ McMillan, SJ Benbow, R Uhrich, A Saxton, M Baum, T Strovas, ...
Brain 146 (8), 3206-3220, 2023
92023
Compositions and Methods for Suppressing MSUT2
B Kraemer, JM Wheeler, P McMillan, TJ Strovas, J Baker
US Patent App. 17/929,867, 2023
12023
Sut-6/NIPP1 modulates tau toxicity
RL Kow, AH Black, BP Henderson, BC Kraemer
Human Molecular Genetics 32 (14), 2292-2306, 2023
2023
SPOP loss of function protects against tauopathy
RJ Eck, RL Kow, AH Black, NF Liachko, BC Kraemer
Proceedings of the National Academy of Sciences 120 (1), e2207250120, 2023
32023
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity
HN Currey, BC Kraemer, NF Liachko
Micropublication Biology 2023, 2023
2023
The role of Tau RNA complex formation in tau function and tauopathy disorders
P McMillan, SJ Benbow, R Uhrich, M Baum, TJ Strovas, JD Baker, ...
Alzheimer's & Dementia 18, e065960, 2022
2022
The CUL3 adaptor protein SPOP plays a role in tauopathy mechanisms
R Eck, BC Kraemer
Alzheimer's & Dementia 18, e069083, 2022
2022
Compositions and methods for suppressing MSUT2
B Kraemer, JM Wheeler, P McMillan, TJ Strovas, J Baker
US Patent 11,439,658, 2022
12022
TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans
CS Latimer, JG Stair, JC Hincks, HN Currey, TD Bird, CD Keene, ...
Disease Models & Mechanisms 15 (4), dmm049323, 2022
192022
Loss of aly/ALYREF suppresses toxicity in both tau and TDP-43 models of neurodegeneration
RL Kow, AH Black, AD Saxton, NF Liachko, BC Kraemer
Geroscience 44 (2), 747-761, 2022
42022
Compositions and methods for suppressing msut2
JD Baker, RL Uhrich, TJ Stovas, AD Saxton, BC Kraemer
US Patent App. 17/319,500, 2021
2021
TDP‐43 promotes pathological tau phosphorylation and selective neurotoxicity in C. elegans
CS Latimer, CD Keene, BC Kraemer, NF Liachko
Alzheimer's & Dementia 17, e058137, 2021
12021
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