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Eric A. Kumar
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Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design
Z Yuan, EA Kumar, SJ Campbell, NY Palermo, S Kizhake, JNM Glover, ...
ACS medicinal chemistry letters 2 (10), 764-767, 2011
252011
NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)
CH Schein, N Oezguen, DV Filippov, A Paul, E Kumar, W Braun
Peptides 31 (8), 1441-1448, 2010
232010
The paradox of conformational constraint in the design of Cbl (TKB)-binding peptides
EA Kumar, Q Chen, S Kizhake, C Kolar, M Kang, CA Chang, ...
Scientific reports 3 (1), 1639, 2013
212013
Structure–activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1
Z Yuan, EA Kumar, S Kizhake, A Natarajan
Journal of medicinal chemistry 54 (12), 4264-4268, 2011
192011
High-throughput fluorescence polarization assay to identify inhibitors of Cbl (TKB)–protein tyrosine kinase interactions
EA Kumar, CD Charvet, GL Lokesh, A Natarajan
Analytical biochemistry 411 (2), 254-260, 2011
152011
Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain
EA Kumar, Z Yuan, NY Palermo, L Dong, G Ahmad, GL Lokesh, C Kolar, ...
Journal of medicinal chemistry 55 (7), 3583-3587, 2012
142012
Structural characterization of BRCT–tetrapeptide binding interactions
PRB Joseph, Z Yuan, EA Kumar, GL Lokesh, S Kizhake, K Rajarathnam, ...
Biochemical and biophysical research communications 393 (2), 207-210, 2010
142010
Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase
A Piserchio, EA Isiorho, K Long, AL Bohanon, EA Kumar, N Will, ...
Science Advances 8 (27), eabo2039, 2022
72022
The role of calcium in the interaction between calmodulin and a minimal functional construct of eukaryotic elongation factor 2 kinase
K Lee, EA Kumar, KN Dalby, R Ghose
Protein Science 28 (12), 2089-2098, 2019
72019
Structural dynamics of the complex of calmodulin with a minimal functional construct of eukaryotic elongation factor 2 kinase and the role of Thr348 autophosphorylation
A Piserchio, K Long, K Lee, EA Kumar, R Abzalimov, KN Dalby, R Ghose
Protein Science 30 (6), 1221-1234, 2021
62021
AMPK can stimulate EEF2 phosphorylation without regulating its cognate kinase EEF2K
EA Kumar, D Giles, K Dalby
The FASEB Journal 34 (S1), 1-1, 2020
52020
Building cells for quantitative, live-cell analyses of collective motor protein functions
EA Kumar, D Tsao, A Radhakrishnan, M Diehl
Methods in Cell Biology 128, 69-82, 2015
32015
Structural Basis for the Calmodulin-Mediated Activation of eEF-2K
A Piserchio, EA Isiorho, K Long, AL Bohanon, EA Kumar, N Will, ...
bioRxiv, 2022.01. 15.476372, 2022
2022
Motor Mutants bring Wild-Type Motors to a Halt Stochastically
EA Kumar, DS Tsao, MR Diehl
Biophysical Journal 107 (2), 279-281, 2014
2014
Synthetic Tools for Delineating Multiple Motor Functions in Living Cells
MR Diehl, DS Tsao, E Kumar
Biophysical Journal 106 (2), 362a, 2014
2014
Design and Development of Inhibitors of CBL (TKB)-protein Interactions
EA Kumar
University of Nebraska Medical Center, 2013
2013
Rational design and development of peptidomimetic Cbl inhibitors
EA Kumar, Q Chen, A Natarajan
BIOPOLYMERS 96 (4), 460-460, 2011
2011
Structure activity relationship studies to probe the phosphoprotein binding site on the BRCT domains of BRCA1
Z Yuan, EA Kumar, S Kizhake, A Natarajan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 2009
2009
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