Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design Z Yuan, EA Kumar, SJ Campbell, NY Palermo, S Kizhake, JNM Glover, ... ACS medicinal chemistry letters 2 (10), 764-767, 2011 | 25 | 2011 |
NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU) CH Schein, N Oezguen, DV Filippov, A Paul, E Kumar, W Braun Peptides 31 (8), 1441-1448, 2010 | 23 | 2010 |
The paradox of conformational constraint in the design of Cbl (TKB)-binding peptides EA Kumar, Q Chen, S Kizhake, C Kolar, M Kang, CA Chang, ... Scientific reports 3 (1), 1639, 2013 | 21 | 2013 |
Structure–activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1 Z Yuan, EA Kumar, S Kizhake, A Natarajan Journal of medicinal chemistry 54 (12), 4264-4268, 2011 | 19 | 2011 |
High-throughput fluorescence polarization assay to identify inhibitors of Cbl (TKB)–protein tyrosine kinase interactions EA Kumar, CD Charvet, GL Lokesh, A Natarajan Analytical biochemistry 411 (2), 254-260, 2011 | 15 | 2011 |
Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain EA Kumar, Z Yuan, NY Palermo, L Dong, G Ahmad, GL Lokesh, C Kolar, ... Journal of medicinal chemistry 55 (7), 3583-3587, 2012 | 14 | 2012 |
Structural characterization of BRCT–tetrapeptide binding interactions PRB Joseph, Z Yuan, EA Kumar, GL Lokesh, S Kizhake, K Rajarathnam, ... Biochemical and biophysical research communications 393 (2), 207-210, 2010 | 14 | 2010 |
Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase A Piserchio, EA Isiorho, K Long, AL Bohanon, EA Kumar, N Will, ... Science Advances 8 (27), eabo2039, 2022 | 7 | 2022 |
The role of calcium in the interaction between calmodulin and a minimal functional construct of eukaryotic elongation factor 2 kinase K Lee, EA Kumar, KN Dalby, R Ghose Protein Science 28 (12), 2089-2098, 2019 | 7 | 2019 |
Structural dynamics of the complex of calmodulin with a minimal functional construct of eukaryotic elongation factor 2 kinase and the role of Thr348 autophosphorylation A Piserchio, K Long, K Lee, EA Kumar, R Abzalimov, KN Dalby, R Ghose Protein Science 30 (6), 1221-1234, 2021 | 6 | 2021 |
AMPK can stimulate EEF2 phosphorylation without regulating its cognate kinase EEF2K EA Kumar, D Giles, K Dalby The FASEB Journal 34 (S1), 1-1, 2020 | 5 | 2020 |
Building cells for quantitative, live-cell analyses of collective motor protein functions EA Kumar, D Tsao, A Radhakrishnan, M Diehl Methods in Cell Biology 128, 69-82, 2015 | 3 | 2015 |
Structural Basis for the Calmodulin-Mediated Activation of eEF-2K A Piserchio, EA Isiorho, K Long, AL Bohanon, EA Kumar, N Will, ... bioRxiv, 2022.01. 15.476372, 2022 | | 2022 |
Motor Mutants bring Wild-Type Motors to a Halt Stochastically EA Kumar, DS Tsao, MR Diehl Biophysical Journal 107 (2), 279-281, 2014 | | 2014 |
Synthetic Tools for Delineating Multiple Motor Functions in Living Cells MR Diehl, DS Tsao, E Kumar Biophysical Journal 106 (2), 362a, 2014 | | 2014 |
Design and Development of Inhibitors of CBL (TKB)-protein Interactions EA Kumar University of Nebraska Medical Center, 2013 | | 2013 |
Rational design and development of peptidomimetic Cbl inhibitors EA Kumar, Q Chen, A Natarajan BIOPOLYMERS 96 (4), 460-460, 2011 | | 2011 |
Structure activity relationship studies to probe the phosphoprotein binding site on the BRCT domains of BRCA1 Z Yuan, EA Kumar, S Kizhake, A Natarajan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 2009 | | 2009 |