Stapled peptides with γ‐methylated hydrocarbon chains for the estrogen receptor/coactivator interaction TE Speltz, SW Fanning, CG Mayne, C Fowler, E Tajkhorshid, GL Greene, ... Angewandte Chemie 128 (13), 4324-4327, 2016 | 91 | 2016 |
Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway BG Richardson, AD Jain, TE Speltz, TW Moore Bioorganic & medicinal chemistry letters 25 (11), 2261-2268, 2015 | 74 | 2015 |
A research-based undergraduate organic laboratory project: investigation of a one-pot, multicomponent, environmentally friendly Prins–Friedel–Crafts-type reaction MR Dintzner, JJ Maresh, CR Kinzie, AF Arena, T Speltz Journal of Chemical Education 89 (2), 265-267, 2012 | 37 | 2012 |
Versatile peptide macrocyclization with Diels–Alder cycloadditions JE Montgomery, JA Donnelly, SW Fanning, TE Speltz, X Shangguan, ... Journal of the American Chemical Society 141 (41), 16374-16381, 2019 | 36 | 2019 |
A “cross-stitched” peptide with improved helicity and proteolytic stability TE Speltz, CG Mayne, SW Fanning, Z Siddiqui, E Tajkhorshid, GL Greene, ... Organic & biomolecular chemistry 16 (20), 3702-3706, 2018 | 34 | 2018 |
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction TE Speltz, JM Danes, JD Stender, J Frasor, TW Moore ACS chemical biology 13 (3), 676-684, 2018 | 32 | 2018 |
Recent structural advances in constrained helical peptides KJ Skowron, TE Speltz, TW Moore Medicinal research reviews 39 (2), 749-770, 2019 | 29 | 2019 |
Steroid receptor/coactivator binding inhibitors: An update KJ Skowron, K Booker, C Cheng, S Creed, BP David, PR Lazzara, A Lian, ... Molecular and cellular endocrinology 493, 110471, 2019 | 25 | 2019 |
Chemoselective Zinc/HCl reduction of halogenated β-nitrostyrenes: synthesis of halogenated dopamine analogues JJ Maresh, AA Ralko, TE Speltz, JL Burke, CM Murphy, Z Gaskell, ... Synlett 25 (20), 2891-2894, 2014 | 20 | 2014 |
Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains TE Speltz, Z Qiao, CS Swenson, X Shangguan, JS Coukos, CW Lee, ... Nature biotechnology 41 (4), 541-551, 2023 | 13 | 2023 |
Using tumor explants for imaging mass spectrometry visualization of unlabeled peptides and small molecules BP David, O Dubrovskyi, TE Speltz, JJ Wolff, J Frasor, LM Sanchez, ... ACS medicinal chemistry letters 9 (7), 768-772, 2018 | 9 | 2018 |
Novel Copolymers of Styrene. 4. Halophenoxy Ring-Substituted 2-Cyano-3-phenyl-2-propenamides GB Kharas, NJ Kuffel, T Speltz, E Bittar, D Canby, AE Grecco, AD Jacks, ... Journal of Macromolecular Science, Part A 52 (1), 10-14, 2015 | 4 | 2015 |
Protein targeting with SAF (er) electrophiles TE Speltz, RE Moellering Nature Chemistry 12 (10), 885-887, 2020 | 2 | 2020 |
Synthetic dna binding domains and uses thereof RE Moellering, TE Speltz, S Shangguan US Patent App. 18/038,633, 2024 | | 2024 |
Stapled peptide inhibitors of mutant estrogen receptor/coactivator interactions TE Speltz, JM Danes, SW Fanning, CG Mayne, E Tajkhorshid, GL Greene, ... Cancer Research 78 (13_Supplement), 1810-1810, 2018 | | 2018 |
Optimization of stapled peptide inhibitors of the estrogen receptor/coactivator interaction T Moore, T Speltz, C Mayne, J Danes, S Fanning, B David, G Greene, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Engineering natural sidechains from leucine and isoleucine into" stapling" amino acids to inhibit the estrogen receptor/coactivator interaction T Moore, T Speltz ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |