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Ryan Z Friedman
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Year
Co-opted transposons help perpetuate conserved higher-order chromosomal structures
MNK Choudhary, RZ Friedman, JT Wang, HS Jang, X Zhuo, T Wang
Genome biology 21, 1-14, 2020
902020
Information Content Differentiates Enhancers From Silencers in Mouse Photoreceptors
RZ Friedman, DM Granas, CA Myers, JC Corbo, BA Cohen, MA White
eLife 10, e67403, 2021
232021
Unintended Side Effects of Transformation Are Very Rare in Cryptococcus neoformans
RZ Friedman, SR Gish, H Brown, L Brier, N Howard, TL Doering, ...
G3: Genes, Genomes, Genetics 8 (3), 815-822, 2018
162018
A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo
T Lagunas Jr, SP Plassmeyer, AD Fischer, RZ Friedman, MA Rieger, ...
Communications Biology 6 (1), 1151, 2023
11*2023
Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors
JL Shepherdson, RZ Friedman, Y Zheng, C Sun, IY Oh, DM Granas, ...
Genome Research 34 (2), 243-255, 2024
52024
Transcription factor interactions explain the context-dependent activity of CRX binding sites
KJ Loell, RZ Friedman, CA Myers, JC Corbo, BA Cohen, MA White
PLoS computational biology 20 (1), e1011802, 2024
52024
Active learning of enhancer and silencer regulatory grammar in a developing neural tissue
RZ Friedman, A Ramu, S Lichtarge, Y Wu, L Tripp, D Lyon, CA Myers, ...
bioRxiv, 2023.08. 21.554146, 2023
3*2023
Two non-coding variants associated with isolated orofacial cleft promote binding of transcriptional repressors FOXE1 or ETS2 and reduce expression of IRF6
P Kumari, RZ Friedman, L Pi, S Curtis, K Paraiso, A Visel, L Rhea, ...
bioRxiv, 2024.06. 01.596914, 2024
2024
Iterative Machine Learning of a Cis-Regulatory Grammar
RZ Friedman
Washington University in St. Louis, 2023
2023
Categorizing the Unintended Side Effects of Genetic Transformation
RZ Friedman
2017
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Articles 1–10